STRINGSTRING
FABP3 FABP3 SREBF1 SREBF1 NR1H3 NR1H3 ENSRBIP00000000642 ENSRBIP00000000642 MID1IP1 MID1IP1 ENSRBIP00000001673 ENSRBIP00000001673 CPT1A CPT1A PLIN5 PLIN5 LPGAT1 LPGAT1 MLXIPL MLXIPL FABP5-2 FABP5-2 PRKAG2 PRKAG2 PDK3 PDK3 PPARA PPARA SCAP SCAP ENSRBIP00000007851 ENSRBIP00000007851 MFSD2A MFSD2A ENSRBIP00000009022 ENSRBIP00000009022 SOX9 SOX9 GHSR GHSR SIRT4 SIRT4 PANK2 PANK2 SIRT1 SIRT1 AKT1 AKT1 CEACAM1 CEACAM1 MLYCD MLYCD ADIPOQ ADIPOQ PDK2 PDK2 APPL2 APPL2 IRS1 IRS1 CYP7A1 CYP7A1 FMO1 FMO1 PIBF1 PIBF1 MTLN MTLN APOA5 APOA5 CAV1 CAV1 FABP5 FABP5 LONP2 LONP2 FMO4 FMO4 IRS2 IRS2 PPARGC1A PPARGC1A LOC108521987 LOC108521987 ABCD2 ABCD2 ETFBKMT ETFBKMT IL1B IL1B PPARG-2 PPARG-2 AVPR1A AVPR1A ENSRBIP00000018276 ENSRBIP00000018276 EIF6 EIF6 TYSND1 TYSND1 SLC22A13 SLC22A13 APOC2 APOC2 DGAT2 DGAT2 NR1H2 NR1H2 PTGS2 PTGS2 NR4A3 NR4A3 ERFE ERFE INSIG1 INSIG1 ERLIN2 ERLIN2 ENSRBIP00000028026 ENSRBIP00000028026 FABP1 FABP1 ENSRBIP00000030628 ENSRBIP00000030628 PDK1 PDK1 ANKRD26 ANKRD26 GIP GIP PLA2G3 PLA2G3 TRIB3 TRIB3 ABCB11 ABCB11 WDTC1 WDTC1 AKT2 AKT2 FMO2 FMO2 ERLIN1 ERLIN1 NCOR1 NCOR1 PDK4 PDK4 PPARD PPARD ACACB ACACB AVP AVP SLC45A3 SLC45A3 PPARG PPARG CD74 CD74 ENSRBIP00000038661 ENSRBIP00000038661 BRCA1 BRCA1 LOC108540985 LOC108540985 ABCD1 ABCD1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FABP3Fatty acid binding protein 3; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (133 aa)
SREBF1Sterol regulatory element binding transcription factor 1. (1047 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (441 aa)
ENSRBIP00000000642FABP domain-containing protein. (121 aa)
MID1IP1MID1 interacting protein 1. (183 aa)
ENSRBIP00000001673Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (101 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (762 aa)
PLIN5Perilipin; Belongs to the perilipin family. (462 aa)
LPGAT1Lysophosphatidylglycerol acyltransferase 1. (357 aa)
MLXIPLMLX interacting protein like. (798 aa)
FABP5-2FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa)
PRKAG2Protein kinase AMP-activated non-catalytic subunit gamma 2. (371 aa)
PDK3Protein-serine/threonine kinase. (363 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
SCAPSREBF chaperone. (1469 aa)
ENSRBIP00000007851ANK_REP_REGION domain-containing protein. (97 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (530 aa)
ENSRBIP00000009022CCDC144C domain-containing protein. (348 aa)
SOX9SRY-box transcription factor 9. (305 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
PANK2Pantothenate kinase 2. (574 aa)
SIRT1Sirtuin 1. (731 aa)
AKT1AKT serine/threonine kinase 1. (486 aa)
CEACAM1Uncharacterized protein. (525 aa)
MLYCDMalonyl-CoA decarboxylase. (493 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (275 aa)
PDK2Protein-serine/threonine kinase. (559 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (664 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
CYP7A1Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. (405 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (691 aa)
MTLNMitoregulin. (111 aa)
APOA5Apolipoprotein A5. (366 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
FABP5FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (115 aa)
LONP2Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (852 aa)
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (558 aa)
IRS2Insulin receptor substrate 2. (904 aa)
PPARGC1APPARG coactivator 1 alpha. (798 aa)
LOC108521987DUF3496 domain-containing protein. (153 aa)
ABCD2ATP binding cassette subfamily D member 2. (740 aa)
ETFBKMTElectron transfer flavoprotein subunit beta lysine methyltransferase. (262 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
PPARG-2Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (217 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (421 aa)
ENSRBIP00000018276Uncharacterized protein. (194 aa)
EIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa)
TYSND1Trypsin domain containing 1. (566 aa)
SLC22A13Solute carrier family 22 member 13. (551 aa)
APOC2Apolipoprotein C2. (101 aa)
DGAT2Diacylglycerol O-acyltransferase 2. (388 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (637 aa)
ERFEErythroferrone. (348 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (283 aa)
ERLIN2ER lipid raft associated 2. (380 aa)
ENSRBIP00000028026Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (139 aa)
FABP1Fatty acid binding protein 1. (127 aa)
ENSRBIP00000030628FABP domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (118 aa)
PDK1Protein-serine/threonine kinase. (436 aa)
ANKRD26Ankyrin repeat domain 26. (1667 aa)
GIPGastric inhibitory polypeptide. (151 aa)
PLA2G3Phospholipase A2 group III. (508 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
ABCB11ATP binding cassette subfamily B member 11. (1309 aa)
WDTC1WD and tetratricopeptide repeats 1. (666 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa)
ERLIN1ER lipid raft associated 1. (348 aa)
NCOR1Nuclear receptor corepressor 1. (2441 aa)
PDK4Protein-serine/threonine kinase. (411 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
ACACBAcetyl-CoA carboxylase beta. (2458 aa)
AVPArginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
SLC45A3Solute carrier family 45 member 3. (553 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (298 aa)
CD74CD74 molecule. (294 aa)
ENSRBIP00000038661Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (104 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1818 aa)
LOC108540985UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (534 aa)
ABCD1ATP binding cassette subfamily D member 1. (734 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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