STRINGSTRING
KRT8 KRT8 ASAH1 ASAH1 KRT82 KRT82 KRT79 KRT79 ST14 ST14 WNT5A WNT5A KRT7 KRT7 LOC108518860 LOC108518860 TSG101 TSG101 DNASE1L2 DNASE1L2 LATS2 LATS2 ABCA12 ABCA12 KRT4 KRT4 CYP26B1 CYP26B1 KRT10 KRT10 KRT73 KRT73 SAV1 SAV1 SHARPIN SHARPIN TGM1 TGM1 PLEC PLEC PIP5K1A PIP5K1A DSP DSP KRT86 KRT86 KRT83 KRT83 CNFN CNFN KRT16 KRT16 CLIC4 CLIC4 TXNIP TXNIP EXPH5 EXPH5 LATS1 LATS1 INTU INTU SCEL SCEL KRT71 KRT71 ENSRBIP00000027759 ENSRBIP00000027759 FOSL2 FOSL2 KRTAP6-3 KRTAP6-3 CASP14 CASP14 ENSRBIP00000025889 ENSRBIP00000025889 ENSRBIP00000025870 ENSRBIP00000025870 ENSRBIP00000025472 ENSRBIP00000025472 BCL11B BCL11B YAP1 YAP1 CERS3 CERS3 LIPK LIPK LOC108518859 LOC108518859 WNT16 WNT16 KRTAP6-1 KRTAP6-1 KRT2 KRT2 ACER1 ACER1 LIPN LIPN ENSRBIP00000023123 ENSRBIP00000023123 KRT78 KRT78 LOC108525471 LOC108525471 NOTCH1 NOTCH1 EZH2 EZH2 OPN3 OPN3 ENSRBIP00000020509 ENSRBIP00000020509 KRT6A KRT6A ENSRBIP00000000813 ENSRBIP00000000813 PPL PPL ENSRBIP00000001234 ENSRBIP00000001234 EVPL EVPL PPP3CA PPP3CA SFN SFN PPP3CA-2 PPP3CA-2 SPRR2A SPRR2A SPRR2G SPRR2G IFT74 IFT74 LIPM LIPM CDH3 CDH3 KRT74 KRT74 KRT85 KRT85 FOXN1 FOXN1 LOC108521570 LOC108521570 SPRR2B SPRR2B KRT72 KRT72 ENSRBIP00000007626 ENSRBIP00000007626 KDF1 KDF1 ADAM9 ADAM9 CSTA CSTA EREG EREG KRT75 KRT75 ANXA1 ANXA1 AKR1C3 AKR1C3 FLNB FLNB KRT5 KRT5 KRT84 KRT84 BCR BCR KRT76 KRT76 TP63 TP63 KRT81 KRT81 IRF6 IRF6 ENSRBIP00000011812 ENSRBIP00000011812 JAG1 JAG1 KRT80 KRT80 IVL IVL KRT77 KRT77 KLK5 KLK5 MED1 MED1 UGCG UGCG ENSRBIP00000015707 ENSRBIP00000015707 KAZN KAZN ENSRBIP00000016325 ENSRBIP00000016325 PPHLN1 PPHLN1 TMEM79 TMEM79 PNPLA1 PNPLA1 TCHH TCHH PAX6 PAX6 DSG4 DSG4 KRT1 KRT1 EPHA2 EPHA2 KRT3 KRT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KRT8Keratin 8; Belongs to the intermediate filament family. (499 aa)
ASAH1N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (411 aa)
KRT82Keratin 82; Belongs to the intermediate filament family. (513 aa)
KRT79Keratin 79; Belongs to the intermediate filament family. (528 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
KRT7Keratin 7; Belongs to the intermediate filament family. (474 aa)
LOC108518860Protein S100-A7. (101 aa)
TSG101Tumor susceptibility 101. (381 aa)
DNASE1L2Deoxyribonuclease; Belongs to the DNase I family. (278 aa)
LATS2Non-specific serine/threonine protein kinase. (1083 aa)
ABCA12ATP binding cassette subfamily A member 12. (2595 aa)
KRT4Keratin 4; Belongs to the intermediate filament family. (520 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (512 aa)
KRT10Keratin 10; Belongs to the intermediate filament family. (558 aa)
KRT73Keratin 73; Belongs to the intermediate filament family. (540 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
SHARPINSHANK associated RH domain interactor. (384 aa)
TGM1Transglutaminase 1. (808 aa)
PLECPlectin. (4578 aa)
PIP5K1APhosphatidylinositol-4-phosphate 5-kinase type 1 alpha. (562 aa)
DSPDesmoplakin. (2857 aa)
KRT86Keratin 86; Belongs to the intermediate filament family. (436 aa)
KRT83Keratin 83; Belongs to the intermediate filament family. (493 aa)
CNFNUncharacterized protein. (97 aa)
KRT16Keratin 16; Belongs to the intermediate filament family. (478 aa)
CLIC4Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (253 aa)
TXNIPThioredoxin interacting protein. (391 aa)
EXPH5Exophilin 5. (1964 aa)
LATS1Large tumor suppressor kinase 1. (1179 aa)
INTUInturned planar cell polarity protein. (933 aa)
SCELSciellin. (698 aa)
KRT71Keratin 71; Belongs to the intermediate filament family. (525 aa)
ENSRBIP00000027759IF rod domain-containing protein; Belongs to the intermediate filament family. (475 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (326 aa)
KRTAP6-3Keratin associated protein 6-3. (106 aa)
CASP14Caspase 14; Belongs to the peptidase C14A family. (242 aa)
ENSRBIP00000025889PIPK domain-containing protein. (563 aa)
ENSRBIP00000025870Uncharacterized protein. (236 aa)
ENSRBIP00000025472IF rod domain-containing protein; Belongs to the intermediate filament family. (245 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (864 aa)
YAP1Yes associated protein 1. (326 aa)
CERS3Ceramide synthase 3. (385 aa)
LIPKLipase; Belongs to the AB hydrolase superfamily. Lipase family. (399 aa)
LOC108518859Protein S100; Belongs to the S-100 family. (101 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
KRTAP6-1Keratin associated protein 6-1. (69 aa)
KRT2Keratin 2; Belongs to the intermediate filament family. (626 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
LIPNLipase; Belongs to the AB hydrolase superfamily. Lipase family. (390 aa)
ENSRBIP00000023123Uncharacterized protein. (391 aa)
KRT78Keratin 78; Belongs to the intermediate filament family. (514 aa)
LOC108525471Uncharacterized protein. (356 aa)
NOTCH1Notch receptor 1. (2438 aa)
EZH2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (767 aa)
OPN3Opsin 3; Belongs to the G-protein coupled receptor 1 family. (449 aa)
ENSRBIP00000020509IF rod domain-containing protein; Belongs to the intermediate filament family. (409 aa)
KRT6AIF rod domain-containing protein; Belongs to the intermediate filament family. (527 aa)
ENSRBIP00000000813IF rod domain-containing protein; Belongs to the intermediate filament family. (475 aa)
PPLPeriplakin. (1756 aa)
ENSRBIP00000001234Uncharacterized protein. (93 aa)
EVPLEnvoplakin. (2033 aa)
PPP3CASerine/threonine-protein phosphatase. (310 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
PPP3CA-2Uncharacterized protein. (70 aa)
SPRR2ASmall proline rich protein 2A. (72 aa)
SPRR2GSmall proline rich protein 2G. (73 aa)
IFT74Intraflagellar transport 74. (599 aa)
LIPMLipase; Belongs to the AB hydrolase superfamily. Lipase family. (427 aa)
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (829 aa)
KRT74Keratin 74; Belongs to the intermediate filament family. (543 aa)
KRT85Keratin 85; Belongs to the intermediate filament family. (507 aa)
FOXN1Forkhead box N1. (648 aa)
LOC108521570IF rod domain-containing protein; Belongs to the intermediate filament family. (552 aa)
SPRR2BUncharacterized protein. (72 aa)
KRT72Keratin 72; Belongs to the intermediate filament family. (511 aa)
ENSRBIP00000007626PIPK domain-containing protein. (475 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
ADAM9ADAM metallopeptidase domain 9. (819 aa)
CSTACystatin A; Belongs to the cystatin family. (98 aa)
EREGEpiregulin. (169 aa)
KRT75Keratin 75; Belongs to the intermediate filament family. (551 aa)
ANXA1Annexin. (346 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (343 aa)
FLNBFilamin B. (2633 aa)
KRT5Keratin 5; Belongs to the intermediate filament family. (589 aa)
KRT84Keratin 84; Belongs to the intermediate filament family. (600 aa)
BCRBCR activator of RhoGEF and GTPase. (1089 aa)
KRT76Keratin 76; Belongs to the intermediate filament family. (637 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
KRT81Keratin 81; Belongs to the intermediate filament family. (505 aa)
IRF6Interferon regulatory factor 6. (467 aa)
ENSRBIP00000011812IF rod domain-containing protein; Belongs to the intermediate filament family. (402 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
KRT80Keratin 80; Belongs to the intermediate filament family. (452 aa)
IVLInvolucrin_N domain-containing protein. (453 aa)
KRT77Keratin 77; Belongs to the intermediate filament family. (579 aa)
KLK5Kallikrein related peptidase 5; Belongs to the peptidase S1 family. (293 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1547 aa)
UGCGUDP-glucose ceramide glucosyltransferase. (374 aa)
ENSRBIP00000015707Uncharacterized protein. (239 aa)
KAZNKazrin, periplakin interacting protein. (770 aa)
ENSRBIP00000016325S_100 domain-containing protein. (92 aa)
PPHLN1Periphilin 1. (427 aa)
TMEM79Uncharacterized protein. (354 aa)
PNPLA1Patatin like phospholipase domain containing 1. (533 aa)
TCHHEF-hand domain-containing protein. (1079 aa)
PAX6Paired box 6. (462 aa)
DSG4Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1055 aa)
KRT1Keratin 1; Belongs to the intermediate filament family. (642 aa)
EPHA2EPH receptor A2. (1036 aa)
KRT3Keratin 3; Belongs to the intermediate filament family. (629 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.