39 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PARP1	Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
	LCOR	Ligand dependent nuclear receptor corepressor. (1556 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (595 aa)
	SRC	Tyrosine-protein kinase. (627 aa)
	NRIP1	Nuclear receptor interacting protein 1. (1155 aa)
	PADI2	Peptidyl arginine deiminase 2. (723 aa)
	NKX3-1	NK3 homeobox 1. (230 aa)
	ISL1	ISL LIM homeobox 1. (349 aa)
	PPID	Peptidylprolyl isomerase D. (370 aa)
	LEF1	Lymphoid enhancer binding factor 1. (398 aa)
	FOXL2	Forkhead box L2. (427 aa)
	SRARP	Steroid receptor associated and regulated protein. (169 aa)
	MED1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1547 aa)
	WIPI1	WD repeat domain, phosphoinositide interacting 1. (446 aa)
	DCAF13	DDB1 and CUL4 associated factor 13. (579 aa)
	DDX54	ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (884 aa)
	NSD1	Nuclear receptor binding SET domain protein 1. (2652 aa)
	DNAAF4	Dynein axonemal assembly factor 4. (370 aa)
	XBP1	BZIP domain-containing protein. (380 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	STRN	Striatin. (751 aa)
	NCOA1	Nuclear receptor coactivator. (1433 aa)
	MMS19	MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa)
	RERG	RAS like estrogen regulated growth inhibitor. (199 aa)
	PPARGC1B	PPARG coactivator 1 beta. (1024 aa)
	DCAF1	DDB1 and CUL4 associated factor 1. (1475 aa)
	TACC1	Transforming acidic coiled-coil containing protein 1. (732 aa)
	ZNF366	Zinc finger protein 366. (745 aa)
	NCOA6	Nuclear receptor coactivator 6. (2068 aa)
	TRIP4	Thyroid hormone receptor interactor 4. (510 aa)
	LATS1	Large tumor suppressor kinase 1. (1179 aa)
	ARID5A	AT-rich interaction domain 5A. (702 aa)
	PRMT2	Protein arginine methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (446 aa)
	TAF10	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (229 aa)
	PAGR1	PAXIP1 associated glutamate rich protein 1. (254 aa)
	ENSRBIP00000036594	Uncharacterized protein. (294 aa)
	WBP2	WW domain binding protein 2. (261 aa)
	CCDC62	Coiled-coil domain containing 62. (568 aa)
	CNOT1	CCR4-NOT transcription complex subunit 1. (2355 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTNNB1	ESR1	ENSRBIP00000022705	ENSRBIP00000002017	Catenin beta 1.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.627
CTNNB1	LEF1	ENSRBIP00000022705	ENSRBIP00000009456	Catenin beta 1.	Lymphoid enhancer binding factor 1.	0.999
CTNNB1	SRC	ENSRBIP00000022705	ENSRBIP00000002089	Catenin beta 1.	Tyrosine-protein kinase.	0.974
DCAF1	DCAF13	ENSRBIP00000026673	ENSRBIP00000016546	DDB1 and CUL4 associated factor 1.	DDB1 and CUL4 associated factor 13.	0.596
DCAF13	DCAF1	ENSRBIP00000016546	ENSRBIP00000026673	DDB1 and CUL4 associated factor 13.	DDB1 and CUL4 associated factor 1.	0.596
DCAF13	DDX54	ENSRBIP00000016546	ENSRBIP00000017049	DDB1 and CUL4 associated factor 13.	ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.	0.674
DCAF13	NCOA6	ENSRBIP00000016546	ENSRBIP00000027786	DDB1 and CUL4 associated factor 13.	Nuclear receptor coactivator 6.	0.825
DDX54	DCAF13	ENSRBIP00000017049	ENSRBIP00000016546	ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily.	DDB1 and CUL4 associated factor 13.	0.674
ESR1	CTNNB1	ENSRBIP00000002017	ENSRBIP00000022705	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Catenin beta 1.	0.627
ESR1	LCOR	ENSRBIP00000002017	ENSRBIP00000000057	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Ligand dependent nuclear receptor corepressor.	0.480
ESR1	LEF1	ENSRBIP00000002017	ENSRBIP00000009456	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Lymphoid enhancer binding factor 1.	0.467
ESR1	MED1	ENSRBIP00000002017	ENSRBIP00000014931	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.992
ESR1	NCOA1	ENSRBIP00000002017	ENSRBIP00000022859	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor coactivator.	0.998
ESR1	NCOA6	ENSRBIP00000002017	ENSRBIP00000027786	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor coactivator 6.	0.655
ESR1	NRIP1	ENSRBIP00000002017	ENSRBIP00000002278	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor interacting protein 1.	0.945
ESR1	PPARGC1B	ENSRBIP00000002017	ENSRBIP00000025696	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	PPARG coactivator 1 beta.	0.411
ESR1	PPID	ENSRBIP00000002017	ENSRBIP00000009322	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Peptidylprolyl isomerase D.	0.755
ESR1	SRC	ENSRBIP00000002017	ENSRBIP00000002089	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Tyrosine-protein kinase.	0.995
ESR1	STRN	ENSRBIP00000002017	ENSRBIP00000022835	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Striatin.	0.793
ESR1	TAF10	ENSRBIP00000002017	ENSRBIP00000036073	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family.	0.525