(19 nodes) Notochord development network (Rhinopithecus bieti)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CRB2	Crumbs cell polarity complex component 2. (1108 aa)
	COL13A1	Collagen type XIII alpha 1 chain. (717 aa)
	GLI1	GLI family zinc finger 1. (1106 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
	EFNA1	Ephrin A1; Belongs to the ephrin family. (156 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	COL2A1	Collagen type II alpha 1 chain. (1487 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (231 aa)
	PPP1R35	Protein phosphatase 1 regulatory subunit 35. (252 aa)
	NOTO	Notochord homeobox. (251 aa)
	EPHA2	EPH receptor A2. (1036 aa)
	GDF3	Growth differentiation factor 3. (364 aa)
	LOC108525471	Uncharacterized protein. (356 aa)
	COBL	Cordon-bleu WH2 repeat protein. (1317 aa)
	YAP1	Yes associated protein 1. (326 aa)
	STIL	STIL centriolar assembly protein. (1280 aa)
	TBXT	T-box transcription factor T. (435 aa)
	TEAD2	TEA domain transcription factor 2. (390 aa)
	ID3	Inhibitor of DNA binding 3, HLH protein. (119 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFNA1	EPHA2	ENSRBIP00000041626	ENSRBIP00000018496	Ephrin A1; Belongs to the ephrin family.	EPH receptor A2.	0.992
EPHA2	EFNA1	ENSRBIP00000018496	ENSRBIP00000041626	EPH receptor A2.	Ephrin A1; Belongs to the ephrin family.	0.992
LOC108525471	TEAD2	ENSRBIP00000022332	ENSRBIP00000028416	Uncharacterized protein.	TEA domain transcription factor 2.	0.851
NOTO	TBXT	ENSRBIP00000006017	ENSRBIP00000026263	Notochord homeobox.	T-box transcription factor T.	0.573
NOTO	TEAD2	ENSRBIP00000006017	ENSRBIP00000028416	Notochord homeobox.	TEA domain transcription factor 2.	0.424
PPP1R35	STIL	ENSRBIP00000005609	ENSRBIP00000043401	Protein phosphatase 1 regulatory subunit 35.	STIL centriolar assembly protein.	0.567
STIL	PPP1R35	ENSRBIP00000043401	ENSRBIP00000005609	STIL centriolar assembly protein.	Protein phosphatase 1 regulatory subunit 35.	0.567
TBXT	NOTO	ENSRBIP00000026263	ENSRBIP00000006017	T-box transcription factor T.	Notochord homeobox.	0.573
TEAD2	LOC108525471	ENSRBIP00000028416	ENSRBIP00000022332	TEA domain transcription factor 2.	Uncharacterized protein.	0.851
TEAD2	NOTO	ENSRBIP00000028416	ENSRBIP00000006017	TEA domain transcription factor 2.	Notochord homeobox.	0.424
TEAD2	YAP1	ENSRBIP00000028416	ENSRBIP00000025082	TEA domain transcription factor 2.	Yes associated protein 1.	0.851
WNT11	WNT5A	ENSRBIP00000038642	ENSRBIP00000041095	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.504
WNT5A	WNT11	ENSRBIP00000041095	ENSRBIP00000038642	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.504
YAP1	TEAD2	ENSRBIP00000025082	ENSRBIP00000028416	Yes associated protein 1.	TEA domain transcription factor 2.	0.851