28 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	SHH	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (427 aa)
	BCL2	BCL2 apoptosis regulator. (239 aa)
	TP63	Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
	FOXE1	Forkhead box E1. (337 aa)
	SNAI1	Snail family transcriptional repressor 1. (264 aa)
	SOSTDC1	Sclerostin domain containing 1. (230 aa)
	KRT28	Keratin 28; Belongs to the intermediate filament family. (464 aa)
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	NGFR	Nerve growth factor receptor. (427 aa)
	WNT10A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa)
	GLI2	GLI family zinc finger 2. (1581 aa)
	KRT25	Keratin 25; Belongs to the intermediate filament family. (450 aa)
	SMO	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
	EXT1	Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
	KRT27	Keratin 27; Belongs to the intermediate filament family. (459 aa)
	INTU	Inturned planar cell polarity protein. (933 aa)
	KRT71	Keratin 71; Belongs to the intermediate filament family. (525 aa)
	DLX3	Distal-less homeobox 3. (287 aa)
	FGF7	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
	ENSRBIP00000023123	Uncharacterized protein. (391 aa)
	FST	Follistatin. (333 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	NOTCH1	Notch receptor 1. (2438 aa)
	TMEM79	Uncharacterized protein. (354 aa)
	FGFR2	Fibroblast growth factor receptor. (840 aa)
	GORAB	Golgin, RAB6 interacting. (393 aa)
	IGFBP5	Insulin like growth factor binding protein 5. (260 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2	CTNNB1	ENSRBIP00000010712	ENSRBIP00000022705	BCL2 apoptosis regulator.	Catenin beta 1.	0.484
CTNNB1	BCL2	ENSRBIP00000022705	ENSRBIP00000010712	Catenin beta 1.	BCL2 apoptosis regulator.	0.484
CTNNB1	FGFR2	ENSRBIP00000022705	ENSRBIP00000014788	Catenin beta 1.	Fibroblast growth factor receptor.	0.480
CTNNB1	NOTCH1	ENSRBIP00000022705	ENSRBIP00000022251	Catenin beta 1.	Notch receptor 1.	0.672
CTNNB1	SHH	ENSRBIP00000022705	ENSRBIP00000011175	Catenin beta 1.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.556
CTNNB1	SMO	ENSRBIP00000022705	ENSRBIP00000041348	Catenin beta 1.	Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family.	0.471
CTNNB1	SNAI1	ENSRBIP00000022705	ENSRBIP00000006765	Catenin beta 1.	Snail family transcriptional repressor 1.	0.577
CTNNB1	WNT10A	ENSRBIP00000022705	ENSRBIP00000043724	Catenin beta 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.443
FGF10	FGF7	ENSRBIP00000001439	ENSRBIP00000026713	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.409
FGF10	FGFR2	ENSRBIP00000001439	ENSRBIP00000014788	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.996
FGF10	NGFR	ENSRBIP00000001439	ENSRBIP00000043342	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Nerve growth factor receptor.	0.686
FGF10	SHH	ENSRBIP00000001439	ENSRBIP00000011175	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.580
FGF7	FGF10	ENSRBIP00000026713	ENSRBIP00000001439	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.409
FGF7	FGFR2	ENSRBIP00000026713	ENSRBIP00000014788	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor receptor.	0.987
FGF7	NGFR	ENSRBIP00000026713	ENSRBIP00000043342	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Nerve growth factor receptor.	0.686
FGF7	SHH	ENSRBIP00000026713	ENSRBIP00000011175	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.452
FGFR2	CTNNB1	ENSRBIP00000014788	ENSRBIP00000022705	Fibroblast growth factor receptor.	Catenin beta 1.	0.480
FGFR2	FGF10	ENSRBIP00000014788	ENSRBIP00000001439	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.996
FGFR2	FGF7	ENSRBIP00000014788	ENSRBIP00000026713	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.987
GLI2	SHH	ENSRBIP00000043119	ENSRBIP00000011175	GLI family zinc finger 2.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.691