19 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	SCTR	Secretin receptor; Belongs to the G-protein coupled receptor 2 family. (443 aa)
	CARTPT	CART prepropeptide. (116 aa)
	POMC	Proopiomelanocortin. (251 aa)
	NUCB2	Nucleobindin 2. (420 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (468 aa)
	GHSR	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	SCT	Secretin. (101 aa)
	SLC22A3	Solute carrier family 22 member 3. (556 aa)
	FBN1	Fibrillin 1. (2871 aa)
	SPX	Spexin hormone. (116 aa)
	LEP	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
	HTR4	5-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (428 aa)
	NENF	Neudesin neurotrophic factor; Belongs to the cytochrome b5 family. (170 aa)
	BBS2	Bardet-Biedl syndrome 2 protein homolog. (717 aa)
	GHRL	Ghrelin and obestatin prepropeptide. (117 aa)
	BBS4	Bardet-Biedl syndrome 4. (347 aa)
	MKKS	McKusick-Kaufman syndrome. (570 aa)
	ENSRBIP00000022449	Uncharacterized protein. (254 aa)
	GALP	Galanin like peptide. (115 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BBS2	BBS4	ENSRBIP00000032208	ENSRBIP00000028239	Bardet-Biedl syndrome 2 protein homolog.	Bardet-Biedl syndrome 4.	0.997
BBS2	MKKS	ENSRBIP00000032208	ENSRBIP00000022464	Bardet-Biedl syndrome 2 protein homolog.	McKusick-Kaufman syndrome.	0.436
BBS4	BBS2	ENSRBIP00000028239	ENSRBIP00000032208	Bardet-Biedl syndrome 4.	Bardet-Biedl syndrome 2 protein homolog.	0.997
CARTPT	LEP	ENSRBIP00000001289	ENSRBIP00000041070	CART prepropeptide.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.499
CARTPT	POMC	ENSRBIP00000001289	ENSRBIP00000002977	CART prepropeptide.	Proopiomelanocortin.	0.560
ENSRBIP00000022449	POMC	ENSRBIP00000022449	ENSRBIP00000002977	Uncharacterized protein.	Proopiomelanocortin.	0.540
GALP	SPX	ENSRBIP00000022163	ENSRBIP00000019571	Galanin like peptide.	Spexin hormone.	0.457
GHRL	GHSR	ENSRBIP00000029484	ENSRBIP00000009607	Ghrelin and obestatin prepropeptide.	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.998
GHRL	LEP	ENSRBIP00000029484	ENSRBIP00000041070	Ghrelin and obestatin prepropeptide.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.892
GHRL	POMC	ENSRBIP00000029484	ENSRBIP00000002977	Ghrelin and obestatin prepropeptide.	Proopiomelanocortin.	0.635
GHSR	GHRL	ENSRBIP00000009607	ENSRBIP00000029484	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Ghrelin and obestatin prepropeptide.	0.998
GHSR	LEP	ENSRBIP00000009607	ENSRBIP00000041070	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.430
GHSR	POMC	ENSRBIP00000009607	ENSRBIP00000002977	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Proopiomelanocortin.	0.579
LEP	CARTPT	ENSRBIP00000041070	ENSRBIP00000001289	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	CART prepropeptide.	0.499
LEP	GHRL	ENSRBIP00000041070	ENSRBIP00000029484	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	Ghrelin and obestatin prepropeptide.	0.892
LEP	GHSR	ENSRBIP00000041070	ENSRBIP00000009607	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.430
LEP	POMC	ENSRBIP00000041070	ENSRBIP00000002977	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	Proopiomelanocortin.	0.696
LEP	PPARA	ENSRBIP00000041070	ENSRBIP00000007565	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	Peroxisome proliferator activated receptor alpha.	0.530
MKKS	BBS2	ENSRBIP00000022464	ENSRBIP00000032208	McKusick-Kaufman syndrome.	Bardet-Biedl syndrome 2 protein homolog.	0.436
POMC	CARTPT	ENSRBIP00000002977	ENSRBIP00000001289	Proopiomelanocortin.	CART prepropeptide.	0.560