STRINGSTRING
KANK2 KANK2 GHRL GHRL MN1 MN1 ENSRBIP00000030441 ENSRBIP00000030441 VDR VDR MED1 MED1 GHSR GHSR PPARA PPARA NUCB2 NUCB2 CARTPT CARTPT PRKCG PRKCG BBS2 BBS2 NENF NENF SNAI2 SNAI2 SNW1 SNW1 RXRA RXRA CYP27B1 CYP27B1 MT3 MT3 SPX SPX MKKS MKKS TRIM24 TRIM24 FBN1 FBN1 LEP LEP BBS4 BBS4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KANK2KN motif and ankyrin repeat domains 2. (851 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
MN1MN1 proto-oncogene, transcriptional regulator. (1322 aa)
ENSRBIP00000030441SKIP_SNW domain-containing protein. (530 aa)
VDRVitamin D receptor. (477 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1547 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
NUCB2Nucleobindin 2. (420 aa)
CARTPTCART prepropeptide. (116 aa)
PRKCGProtein kinase C. (726 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (717 aa)
NENFNeudesin neurotrophic factor; Belongs to the cytochrome b5 family. (170 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
SNW1SKIP_SNW domain-containing protein. (536 aa)
RXRARetinoid X receptor alpha. (492 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
MT3Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
SPXSpexin hormone. (116 aa)
MKKSMcKusick-Kaufman syndrome. (570 aa)
TRIM24Tripartite motif containing 24. (1048 aa)
FBN1Fibrillin 1. (2871 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
BBS4Bardet-Biedl syndrome 4. (347 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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