40 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CD86	CD86 molecule. (329 aa)
	ENSRBIP00000002430	Ribosomal_S3_C domain-containing protein. (168 aa)
	PNP	Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa)
	STAT5B	Signal transducer and activator of transcription. (768 aa)
	MALT1	MALT1 paracaspase. (811 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
	CD83	CD83 molecule. (205 aa)
	CD28	CD28 molecule. (220 aa)
	CD3E	CD3e molecule. (198 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
	ENSRBIP00000019290	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (242 aa)
	ENSRBIP00000022247	Uncharacterized protein. (70 aa)
	ENSRBIP00000023617	Uncharacterized protein. (95 aa)
	VTCN1	V-set domain containing T cell activation inhibitor 1. (285 aa)
	SASH3	SAM and SH3 domain containing 3. (357 aa)
	ENSRBIP00000027432	Ig-like domain-containing protein. (244 aa)
	SPTBN1	Spectrin beta chain; Belongs to the spectrin family. (2366 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa)
	TRAF2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
	ENSRBIP00000034301	Ribosomal_S3_C domain-containing protein. (253 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
	ENSRBIP00000037360	KH type-2 domain-containing protein. (143 aa)
	STOML2	Stomatin like 2. (361 aa)
	PDE4B	Phosphodiesterase. (736 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1310 aa)
	CLEC7A	C-type lectin domain containing 7A. (257 aa)
	PDE4D	Phosphodiesterase. (809 aa)
	GLMN	Glomulin, FKBP associated protein. (595 aa)
	RUNX1	RUNX family transcription factor 1. (264 aa)
	PRKD2	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
	CD80	CD80 molecule. (288 aa)
	ANXA1	Annexin. (346 aa)
	ABL1	Tyrosine-protein kinase. (1149 aa)
	RPS3	Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa)
	ENSRBIP00000006958	TNF receptor-associated factor. (473 aa)
	MAP3K7	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
	CARD11	Caspase recruitment domain family member 11. (1154 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (443 aa)
	ENSRBIP00000003252	Uncharacterized protein. (101 aa)
	IRF4	Interferon regulatory factor 4. (450 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	RUNX1	ENSRBIP00000007933	ENSRBIP00000001162	Tyrosine-protein kinase.	RUNX family transcription factor 1.	0.607
ABL1	STAT5B	ENSRBIP00000007933	ENSRBIP00000016396	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.944
ANXA1	CD86	ENSRBIP00000008979	ENSRBIP00000017666	Annexin.	CD86 molecule.	0.414
ANXA1	IL1B	ENSRBIP00000008979	ENSRBIP00000017788	Annexin.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.423
CARD11	CD28	ENSRBIP00000004497	ENSRBIP00000012284	Caspase recruitment domain family member 11.	CD28 molecule.	0.564
CARD11	ENSRBIP00000006958	ENSRBIP00000004497	ENSRBIP00000006958	Caspase recruitment domain family member 11.	TNF receptor-associated factor.	0.665
CARD11	ENSRBIP00000022247	ENSRBIP00000004497	ENSRBIP00000022247	Caspase recruitment domain family member 11.	Uncharacterized protein.	0.414
CARD11	MALT1	ENSRBIP00000004497	ENSRBIP00000016056	Caspase recruitment domain family member 11.	MALT1 paracaspase.	0.993
CARD11	MAP3K7	ENSRBIP00000004497	ENSRBIP00000005150	Caspase recruitment domain family member 11.	Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.	0.765
CARD11	PRKCQ	ENSRBIP00000004497	ENSRBIP00000031048	Caspase recruitment domain family member 11.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.993
CARD11	RIPK2	ENSRBIP00000004497	ENSRBIP00000003947	Caspase recruitment domain family member 11.	Receptor interacting serine/threonine kinase 2.	0.414
CARD11	TRAF6	ENSRBIP00000004497	ENSRBIP00000036224	Caspase recruitment domain family member 11.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.665
CD28	CARD11	ENSRBIP00000012284	ENSRBIP00000004497	CD28 molecule.	Caspase recruitment domain family member 11.	0.564
CD28	CD3E	ENSRBIP00000012284	ENSRBIP00000010972	CD28 molecule.	CD3e molecule.	0.472
CD28	CD80	ENSRBIP00000012284	ENSRBIP00000009172	CD28 molecule.	CD80 molecule.	0.996
CD28	CD86	ENSRBIP00000012284	ENSRBIP00000017666	CD28 molecule.	CD86 molecule.	0.996
CD28	ENSRBIP00000027432	ENSRBIP00000012284	ENSRBIP00000027432	CD28 molecule.	Ig-like domain-containing protein.	0.441
CD28	IL1B	ENSRBIP00000012284	ENSRBIP00000017788	CD28 molecule.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.457
CD28	PRKCQ	ENSRBIP00000012284	ENSRBIP00000031048	CD28 molecule.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.958
CD28	PTPRC	ENSRBIP00000012284	ENSRBIP00000040406	CD28 molecule.	Protein tyrosine phosphatase receptor type C.	0.488