STRINGSTRING
ENG ENG CHD7 CHD7 TBX1 TBX1 ADAMTS9 ADAMTS9 PROX1 PROX1 TFAP2B TFAP2B FOXH1 FOXH1 SEC24B SEC24B FGF8 FGF8 NPRL3 NPRL3 FKBP10 FKBP10 MYLK MYLK TBX2 TBX2 HEY2 HEY2 EFEMP2 EFEMP2 ENSRBIP00000019241 ENSRBIP00000019241 DLL4 DLL4 LRP1 LRP1 BMPR1A BMPR1A PDGFRB PDGFRB JAG1 JAG1 ENSRBIP00000010821 ENSRBIP00000010821 ACVRL1 ACVRL1 COL3A1 COL3A1 HEY1 HEY1 EYA1 EYA1 TGFB2 TGFB2 SOX4 SOX4 SRF SRF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENGEndoglin. (607 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2986 aa)
TBX1T-box transcription factor 1. (371 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1916 aa)
PROX1Prospero homeobox 1. (737 aa)
TFAP2BTranscription factor AP-2 beta. (442 aa)
FOXH1Forkhead box H1. (366 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1252 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (562 aa)
FKBP10Peptidylprolyl isomerase. (582 aa)
MYLKMyosin light chain kinase. (1656 aa)
TBX2T-box transcription factor 2. (686 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
ENSRBIP00000019241Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (458 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
LRP1LDL receptor related protein 1. (4461 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
ENSRBIP00000010821Uncharacterized protein. (441 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
COL3A1Collagen type III alpha 1 chain. (1333 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
SOX4Transcription factor SOX. (475 aa)
SRFSerum response factor. (508 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.