43 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ERN1	Endoplasmic reticulum to nucleus signaling 1. (980 aa)
	VEGFC	Vascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (350 aa)
	PRKD2	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
	FN1	Fibronectin 1. (2477 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	ENSRBIP00000002994	Protein kinase domain-containing protein. (358 aa)
	PRKD1	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (892 aa)
	EGR3	Early growth response 3. (387 aa)
	ANXA1	Annexin. (346 aa)
	VEGFD	Vascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
	AKT1	AKT serine/threonine kinase 1. (486 aa)
	HSPB1	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
	ENSRBIP00000013453	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (173 aa)
	DAB2IP	DAB2 interacting protein. (1156 aa)
	PDGFRB	Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1102 aa)
	PGF	Placental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
	LOC108520322	Fork-head domain-containing protein. (198 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
	MAP2K3	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (394 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
	RELA	Uncharacterized protein. (282 aa)
	VCAM1	Vascular cell adhesion molecule 1. (739 aa)
	XBP1	BZIP domain-containing protein. (380 aa)
	VEGFB	Vascular endothelial growth factor B. (183 aa)
	NOTCH1	Notch receptor 1. (2438 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (923 aa)
	NRP2	Neuropilin; Belongs to the neuropilin family. (930 aa)
	NR4A1	Nuclear receptor subfamily 4 group A member 1. (729 aa)
	SPHK1	Sphingosine kinase 1. (384 aa)
	FLT1	Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1337 aa)
	MAPK14	Mitogen-activated protein kinase. (360 aa)
	ENSRBIP00000029966	PID domain-containing protein. (183 aa)
	ITGB1BP1	PID domain-containing protein. (200 aa)
	GAB1	GRB2 associated binding protein 1. (722 aa)
	MYO1C	Myosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1051 aa)
	RAMP2	Receptor activity modifying protein 2. (175 aa)
	MAPKAPK2	MAPK activated protein kinase 2. (392 aa)
	PIK3CD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
	NUS1	NUS1 dehydrodolichyl diphosphate synthase subunit. (293 aa)
	FLT4	Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1329 aa)
	FLT3	Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1023 aa)
	ENSRBIP00000038500	RHD domain-containing protein. (112 aa)
	SEMA6A	Semaphorin 6A; Belongs to the semaphorin family. (1047 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	ENSRBIP00000013453	ENSRBIP00000010710	ENSRBIP00000013453	AKT serine/threonine kinase 1.	SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family.	0.711
AKT1	ENSRBIP00000038500	ENSRBIP00000010710	ENSRBIP00000038500	AKT serine/threonine kinase 1.	RHD domain-containing protein.	0.432
AKT1	HSPB1	ENSRBIP00000010710	ENSRBIP00000012245	AKT serine/threonine kinase 1.	Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family.	0.711
AKT1	KDR	ENSRBIP00000010710	ENSRBIP00000002621	AKT serine/threonine kinase 1.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.400
AKT1	MAP2K3	ENSRBIP00000010710	ENSRBIP00000017585	AKT serine/threonine kinase 1.	Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily.	0.551
AKT1	MAPK14	ENSRBIP00000010710	ENSRBIP00000027919	AKT serine/threonine kinase 1.	Mitogen-activated protein kinase.	0.623
AKT1	MAPKAPK2	ENSRBIP00000010710	ENSRBIP00000034363	AKT serine/threonine kinase 1.	MAPK activated protein kinase 2.	0.649
AKT1	NOTCH1	ENSRBIP00000010710	ENSRBIP00000022251	AKT serine/threonine kinase 1.	Notch receptor 1.	0.660
AKT1	NR4A1	ENSRBIP00000010710	ENSRBIP00000025052	AKT serine/threonine kinase 1.	Nuclear receptor subfamily 4 group A member 1.	0.499
AKT1	PGF	ENSRBIP00000010710	ENSRBIP00000015280	AKT serine/threonine kinase 1.	Placental growth factor; Belongs to the PDGF/VEGF growth factor family.	0.422
AKT1	PIK3CA	ENSRBIP00000010710	ENSRBIP00000017817	AKT serine/threonine kinase 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.825
AKT1	PIK3CD	ENSRBIP00000010710	ENSRBIP00000035123	AKT serine/threonine kinase 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.637
AKT1	RELA	ENSRBIP00000010710	ENSRBIP00000018109	AKT serine/threonine kinase 1.	Uncharacterized protein.	0.432
AKT1	VCAM1	ENSRBIP00000010710	ENSRBIP00000018479	AKT serine/threonine kinase 1.	Vascular cell adhesion molecule 1.	0.404
AKT1	XBP1	ENSRBIP00000010710	ENSRBIP00000021062	AKT serine/threonine kinase 1.	BZIP domain-containing protein.	0.405
DAB2IP	ERN1	ENSRBIP00000014012	ENSRBIP00000018220	DAB2 interacting protein.	Endoplasmic reticulum to nucleus signaling 1.	0.442
DAB2IP	PIK3CA	ENSRBIP00000014012	ENSRBIP00000017817	DAB2 interacting protein.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.403
DLL4	FLT4	ENSRBIP00000016863	ENSRBIP00000036443	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.523
DLL4	KDR	ENSRBIP00000016863	ENSRBIP00000002621	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.452
DLL4	NOTCH1	ENSRBIP00000016863	ENSRBIP00000022251	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1.	0.978