STRINGSTRING
ZC3H12A ZC3H12A APOD APOD CD36 CD36 EFCAB7 EFCAB7 FERMT1 FERMT1 SHH SHH SIRT6 SIRT6 ENSRBIP00000011695 ENSRBIP00000011695 SMAD3 SMAD3 TGFB1 TGFB1 PRKD1 PRKD1 CABP1 CABP1 RAB23 RAB23 CHP1 CHP1 PIK3R2 PIK3R2 LOC108532627 LOC108532627 ENSRBIP00000004343 ENSRBIP00000004343 PSEN1 PSEN1 HCLS1 HCLS1 NUP54 NUP54 PIK3R1 PIK3R1 ENSRBIP00000000376 ENSRBIP00000000376 ENSRBIP00000000016 ENSRBIP00000000016 CDH1 CDH1 BAG3 BAG3 NOLC1 NOLC1 TPR TPR JUP JUP CHP2 CHP2 MAVS MAVS HYAL2 HYAL2 ENSRBIP00000019981 ENSRBIP00000019981 XBP1 XBP1 PRKCD PRKCD PTGS2 PTGS2 MDFIC MDFIC GLI3 GLI3 NUP58 NUP58 MAPK14 MAPK14 EPM2A EPM2A ECT2 ECT2 UBR5 UBR5 ENSRBIP00000030321 ENSRBIP00000030321 ENSRBIP00000030956 ENSRBIP00000030956 PTPN22 PTPN22 ZIC1 ZIC1 IFNG IFNG PKIG PKIG DMAP1 DMAP1 HDAC3 HDAC3 RBM22 RBM22 ZPR1 ZPR1 SUFU SUFU ANGPT1 ANGPT1 PKIA PKIA BMP4 BMP4 ENSRBIP00000039245 ENSRBIP00000039245 LEP LEP SMO SMO NOLC1-2 NOLC1-2 NF1 NF1 TRIM28 TRIM28
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZC3H12AZinc finger CCCH-type containing 12A. (570 aa)
APODApolipoprotein D. (215 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
EFCAB7EF-hand calcium binding domain 7. (667 aa)
FERMT1Fermitin family member 1. (677 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (427 aa)
SIRT6Sirtuin 6. (355 aa)
ENSRBIP00000011695Small ubiquitin-related modifier. (101 aa)
SMAD3Mothers against decapentaplegic homolog. (480 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (892 aa)
CABP1Uncharacterized protein. (292 aa)
RAB23RAB23, member RAS oncogene family. (242 aa)
CHP1Uncharacterized protein. (163 aa)
PIK3R2Uncharacterized protein. (626 aa)
LOC108532627Hist_deacetyl domain-containing protein. (210 aa)
ENSRBIP00000004343EF-hand domain-containing protein. (165 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (432 aa)
HCLS1Hematopoietic cell-specific Lyn substrate 1. (476 aa)
NUP54Nucleoporin 54. (509 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSRBIP00000000376Uncharacterized protein. (129 aa)
ENSRBIP00000000016Rad60-SLD domain-containing protein. (55 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (924 aa)
BAG3BCL2 associated athanogene 3. (554 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1. (736 aa)
TPRTranslocated promoter region, nuclear basket protein. (2268 aa)
JUPJunction plakoglobin. (709 aa)
CHP2Calcineurin like EF-hand protein 2. (214 aa)
MAVSMitochondrial antiviral signaling protein. (539 aa)
HYAL2Hyaluronidase. (467 aa)
ENSRBIP00000019981Rad60-SLD domain-containing protein. (81 aa)
XBP1BZIP domain-containing protein. (380 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (604 aa)
MDFICMyoD family inhibitor domain containing. (327 aa)
GLI3GLI family zinc finger 3. (1555 aa)
NUP58Nucleoporin 58. (599 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
EPM2AEPM2A glucan phosphatase, laforin. (193 aa)
ECT2Epithelial cell transforming 2. (893 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2727 aa)
ENSRBIP00000030321Uncharacterized protein. (819 aa)
ENSRBIP00000030956Small ubiquitin-related modifier. (123 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (779 aa)
ZIC1Zic family member 1. (447 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (159 aa)
PKIGcAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (467 aa)
HDAC3Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
RBM22RNA binding motif protein 22. (420 aa)
ZPR1ZPR1 zinc finger. (459 aa)
SUFUSUFU negative regulator of hedgehog signaling. (445 aa)
ANGPT1Angiopoietin 1. (498 aa)
PKIAcAMP-dependent protein kinase inhibitor; Belongs to the PKI family. (76 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
ENSRBIP00000039245Ubiquitin-like domain-containing protein. (84 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
NOLC1-2LisH domain-containing protein. (82 aa)
NF1Neurofibromin 1. (2822 aa)
TRIM28Tripartite motif containing 28. (746 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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