STRINGSTRING
DCSTAMP DCSTAMP TGFB1 TGFB1 ITGB8 ITGB8 IRF4 IRF4 PSEN1 PSEN1 RELB RELB BATF BATF CSF2 CSF2 UBD UBD TGFBR2 TGFBR2 LOC108531166 LOC108531166 ENSRBIP00000006958 ENSRBIP00000006958 CAMK4 CAMK4 LTBR LTBR DHRS2 DHRS2 ITGB6 ITGB6 BATF3 BATF3 IL4 IL4 BATF2 BATF2 TRAF6 TRAF6 NOTCH2 NOTCH2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DCSTAMPDendrocyte expressed seven transmembrane protein. (470 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (745 aa)
IRF4Interferon regulatory factor 4. (450 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (432 aa)
RELBRELB proto-oncogene, NF-kB subunit. (541 aa)
BATFBasic leucine zipper ATF-like transcription factor. (125 aa)
CSF2Colony stimulating factor 2. (144 aa)
UBDUbiquitin D. (165 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
LOC108531166AIG1-type G domain-containing protein. (307 aa)
ENSRBIP00000006958TNF receptor-associated factor. (473 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (472 aa)
LTBRLymphotoxin beta receptor. (370 aa)
DHRS2Dehydrogenase/reductase 2. (280 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (771 aa)
BATF3Basic leucine zipper ATF-like transcription factor 3. (126 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
BATF2Basic leucine zipper ATF-like transcription factor 2. (308 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
NOTCH2Notch receptor 2. (2532 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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