46 items (Rhinopithecus bieti) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	SRC	Tyrosine-protein kinase. (627 aa)
	OCLN	Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (522 aa)
	PDE2A	Phosphodiesterase. (944 aa)
	CTNNBIP1	Catenin beta interacting protein 1. (81 aa)
	HRH1	Histamine receptor H1; Belongs to the G-protein coupled receptor 1 family. (489 aa)
	AKAP12	A-kinase anchoring protein 12. (1783 aa)
	BDKRB2	Bradykinin receptor B2; Belongs to the G-protein coupled receptor 1 family. (360 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	SH3GL2	SH3 domain containing GRB2 like 2, endophilin A1. (315 aa)
	MYLK3	Myosin light chain kinase 3. (818 aa)
	ABCC8	ATP binding cassette subfamily C member 8. (1585 aa)
	C2CD4C	C2 calcium dependent domain containing 4C. (401 aa)
	BCR	BCR activator of RhoGEF and GTPase. (1089 aa)
	CLDN5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
	CEACAM1	Uncharacterized protein. (525 aa)
	ARHGAP35	Rho GTPase activating protein 35. (1281 aa)
	BMP6	Bone morphogenetic protein 6. (440 aa)
	TJP3	Tight junction protein 3; Belongs to the MAGUK family. (922 aa)
	SLIT2	Slit guidance ligand 2. (1542 aa)
	NPPB	Natriuretic peptide B. (124 aa)
	GPR4	G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (344 aa)
	DDAH1	Dimethylarginine dimethylaminohydrolase 1. (285 aa)
	APOE	Apolipoprotein E. (317 aa)
	AZU1	Azurocidin 1. (250 aa)
	PTP4A3	Protein tyrosine phosphatase 4A3. (173 aa)
	ADORA2A	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
	TJP1	Tight junction protein 1; Belongs to the MAGUK family. (1737 aa)
	TACR1	Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
	IL18	Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
	TEK	TEK receptor tyrosine kinase. (1123 aa)
	PTPRJ	Protein tyrosine phosphatase receptor type J. (1336 aa)
	FERMT2	Fermitin family member 2. (693 aa)
	PLVAP	Plasmalemma vesicle associated protein. (442 aa)
	YES1	Tyrosine-protein kinase. (480 aa)
	NPR1	Guanylate cyclase. (1061 aa)
	RAMP2	Receptor activity modifying protein 2. (175 aa)
	CDH5	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
	PLEC	Plectin. (4578 aa)
	C2CD4A	C2 calcium dependent domain containing 4A. (323 aa)
	TRPV4	Transient receptor potential cation channel subfamily V member 4; Belongs to the transient receptor (TC 1.A.4) family. (871 aa)
	ENSRBIP00000036977	Protein kinase domain-containing protein. (68 aa)
	ANGPT1	Angiopoietin 1. (498 aa)
	C2CD4B	C2 calcium dependent domain containing 4B. (352 aa)
	AMOT	Angiomotin. (1045 aa)
	ADM	Adrenomedullin. (185 aa)
	TACR2	Tachykinin receptor 2; Belongs to the G-protein coupled receptor 1 family. (398 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADM	RAMP2	ENSRBIP00000041579	ENSRBIP00000033919	Adrenomedullin.	Receptor activity modifying protein 2.	0.997
ANGPT1	CDH5	ENSRBIP00000037572	ENSRBIP00000034414	Angiopoietin 1.	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	0.451
ANGPT1	TEK	ENSRBIP00000037572	ENSRBIP00000028436	Angiopoietin 1.	TEK receptor tyrosine kinase.	0.993
ARHGAP35	SRC	ENSRBIP00000012649	ENSRBIP00000002089	Rho GTPase activating protein 35.	Tyrosine-protein kinase.	0.939
AZU1	SH3GL2	ENSRBIP00000022546	ENSRBIP00000007301	Azurocidin 1.	SH3 domain containing GRB2 like 2, endophilin A1.	0.546
CDH5	ANGPT1	ENSRBIP00000034414	ENSRBIP00000037572	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Angiopoietin 1.	0.451
CDH5	CLDN5	ENSRBIP00000034414	ENSRBIP00000010806	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	0.795
CDH5	OCLN	ENSRBIP00000034414	ENSRBIP00000000174	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family.	0.676
CDH5	PTPRJ	ENSRBIP00000034414	ENSRBIP00000028762	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Protein tyrosine phosphatase receptor type J.	0.531
CDH5	SRC	ENSRBIP00000034414	ENSRBIP00000002089	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Tyrosine-protein kinase.	0.443
CDH5	TEK	ENSRBIP00000034414	ENSRBIP00000028436	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	TEK receptor tyrosine kinase.	0.634
CDH5	TJP1	ENSRBIP00000034414	ENSRBIP00000025653	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	Tight junction protein 1; Belongs to the MAGUK family.	0.742
CLDN5	CDH5	ENSRBIP00000010806	ENSRBIP00000034414	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.	0.795
CLDN5	OCLN	ENSRBIP00000010806	ENSRBIP00000000174	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family.	0.892
CLDN5	PLVAP	ENSRBIP00000010806	ENSRBIP00000030104	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Plasmalemma vesicle associated protein.	0.430
CLDN5	RAMP2	ENSRBIP00000010806	ENSRBIP00000033919	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Receptor activity modifying protein 2.	0.419
CLDN5	TEK	ENSRBIP00000010806	ENSRBIP00000028436	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	TEK receptor tyrosine kinase.	0.419
CLDN5	TJP1	ENSRBIP00000010806	ENSRBIP00000025653	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Tight junction protein 1; Belongs to the MAGUK family.	0.970
CLDN5	TJP3	ENSRBIP00000010806	ENSRBIP00000014966	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family.	Tight junction protein 3; Belongs to the MAGUK family.	0.956
ENSRBIP00000036977	SRC	ENSRBIP00000036977	ENSRBIP00000002089	Protein kinase domain-containing protein.	Tyrosine-protein kinase.	0.669