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| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1515 aa) |
| | UBXN2B | UBX domain protein 2B. (331 aa) |
| | ENSRBIP00000013453 | SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (173 aa) |
| | UEVLD | UEV and lactate/malate dehyrogenase domains. (518 aa) |
| | ASCC2 | Activating signal cointegrator 1 complex subunit 2. (753 aa) |
| | UBXN8 | UBX domain protein 8. (269 aa) |
| | UBE2L6 | Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | GGA3 | Golgi associated, gamma adaptin ear containing, ARF binding protein 3. (723 aa) |
| | SMARCAD1 | Uncharacterized protein. (1026 aa) |
| | ILRUN | Inflammation and lipid regulator with UBA-like and NBR1-like domains. (263 aa) |
| | SHARPIN | SHANK associated RH domain interactor. (384 aa) |
| | RNF185 | Ring finger protein 185. (195 aa) |
| | BIRC2 | Baculoviral IAP repeat containing 2. (618 aa) |
| | USP5 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (858 aa) |
| | STAM | Signal transducing adaptor molecule. (540 aa) |
| | CKS2 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | DNAJB2 | DnaJ heat shock protein family (Hsp40) member B2. (324 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (468 aa) |
| | FAF2 | Fas associated factor family member 2. (445 aa) |
| | TEPSIN | TEPSIN adaptor related protein complex 4 accessory protein. (578 aa) |
| | RBCK1 | RANBP2-type and C3HC4-type zinc finger containing 1. (510 aa) |
| | OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2. (234 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (347 aa) |
| | ENSRBIP00000015197 | Uncharacterized protein. (114 aa) |
| | STAM2 | Signal transducing adaptor molecule 2. (519 aa) |
| | ADRM1 | Adhesion regulating molecule 1. (407 aa) |
| | PLAA | Phospholipase A2 activating protein. (795 aa) |
| | FAF1 | Fas associated factor 1. (536 aa) |
| | WDR92 | WD repeat domain 92. (357 aa) |
| | ENSRBIP00000019157 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (78 aa) |
| | GGA1 | Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (639 aa) |
| | N4BP2L1 | NEDD4 binding protein 2 like 1. (245 aa) |
| | TOM1L1 | Target of myb1 like 1 membrane trafficking protein; Belongs to the TOM1 family. (398 aa) |
| | FBXO7 | F-box protein 7. (522 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (790 aa) |
| | ZFAND2B | Zinc finger AN1-type containing 2B. (257 aa) |
| | ENSRBIP00000021152 | UMA domain-containing protein. (363 aa) |
| | TOLLIP | Toll interacting protein. (274 aa) |
| | N4BP2 | NEDD4 binding protein 2. (1715 aa) |
| | MARCHF7 | Membrane associated ring-CH-type finger 7. (704 aa) |
| | N4BP1 | NEDD4 binding protein 1. (895 aa) |
| | USP13 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (792 aa) |
| | AUP1 | AUP1 lipid droplet regulating VLDL assembly factor. (410 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (707 aa) |
| | VPS28 | VPS28 subunit of ESCRT-I; Belongs to the VPS28 family. (238 aa) |
| | UBAP1 | Ubiquitin associated protein 1. (544 aa) |
| | UBXN7 | UBX domain protein 7. (519 aa) |
| | USP25 | Ubiquitin specific peptidase 25; Belongs to the peptidase C19 family. (1125 aa) |
| | NPLOC4 | NPL4 homolog, ubiquitin recognition factor. (569 aa) |
| | CKS1B | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (79 aa) |
| | NEDD4 | NEDD4 E3 ubiquitin protein ligase. (1224 aa) |
| | NBR1 | NBR1 autophagy cargo receptor. (877 aa) |
| | VPS36 | Vacuolar protein sorting 36 homolog. (386 aa) |
| | AMFR | Autocrine motility factor receptor. (645 aa) |
| | FBXW9 | F-box and WD repeat domain containing 9. (458 aa) |
| | UBAP1L | Ubiquitin associated protein 1 like. (366 aa) |
| | UBR5 | Ubiquitin protein ligase E3 component n-recognin 5. (2727 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (571 aa) |
| | UCHL3 | Ubiquitin carboxyl-terminal hydrolase. (230 aa) |
| | RAD23A | RAD23 homolog A, nucleotide excision repair protein. (363 aa) |
| | SPRTN | SprT-like N-terminal domain. (488 aa) |
| | UBXN10 | UBX domain protein 10. (204 aa) |
| | ENSRBIP00000032894 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (77 aa) |
| | SQSTM1 | Sequestosome 1. (451 aa) |
| | ENSRBIP00000033421 | Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (124 aa) |
| | TOM1 | Target of myb1 membrane trafficking protein; Belongs to the TOM1 family. (492 aa) |
| | UBE2NL | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa) |
| | LOC108520651 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | JARID2 | Jumonji and AT-rich interaction domain containing 2. (1246 aa) |
| | RNF19B | RBR-type E3 ubiquitin transferase. (700 aa) |
| | PRKN | E3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa) |
| | HSPB1 | Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | BUB3 | WD_REPEATS_REGION domain-containing protein. (328 aa) |
| | TRIM32 | Tripartite motif containing 32. (653 aa) |
| | UBXN11 | UBX domain protein 11. (496 aa) |
| | ENSRBIP00000012978 | Uncharacterized protein. (302 aa) |
| | CUEDC1 | CUE domain containing 1. (249 aa) |
| | TP53INP2 | Tumor protein p53 inducible nuclear protein 2. (220 aa) |
| | LOC108532799 | FANCA_interact domain-containing protein. (135 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (480 aa) |
| | LOC108526191 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (112 aa) |
| | UBXN1 | UBX domain protein 1. (310 aa) |
| | HDAC6 | Histone deacetylase 6. (1215 aa) |
| | RAD23B | RAD23 homolog B, nucleotide excision repair protein. (375 aa) |
| | ENSRBIP00000042590 | Uncharacterized protein. (184 aa) |
| | CUEDC2 | CUE domain containing 2. (287 aa) |
| | TOM1L2 | Target of myb1 like 2 membrane trafficking protein; Belongs to the TOM1 family. (536 aa) |
| | TSG101 | Tumor susceptibility 101. (381 aa) |
| | RNFT1 | Ring finger protein, transmembrane 1. (435 aa) |
| | OTUB1 | OTU deubiquitinase, ubiquitin aldehyde binding 1. (286 aa) |
| | GGA2 | Golgi associated, gamma adaptin ear containing, ARF binding protein 2. (613 aa) |
| | RNF31 | Uncharacterized protein. (1072 aa) |
| | UBXN2A | UBX domain protein 2A. (260 aa) |
| | NUP62 | Nucleoporin 62. (442 aa) |
| | ARMC9 | Armadillo repeat containing 9. (840 aa) |
| | MARK4 | Non-specific serine/threonine protein kinase. (701 aa) |
| | MVB12A | Multivesicular body subunit 12A. (265 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (690 aa) |
| | USP16 | Ubiquitin carboxyl-terminal hydrolase 16; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. (822 aa) |
