48 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SOX9	SRY-box transcription factor 9. (305 aa)
	SESN2	Sestrin 2. (450 aa)
	STK3	Serine/threonine kinase 3. (490 aa)
	RPS6KB2	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (485 aa)
	TNFSF11	Tumor necrosis factor ligand superfamily member. (317 aa)
	MKRN2	Makorin ring finger protein 2. (416 aa)
	NRG1	Neuregulin 1. (713 aa)
	AKT1	AKT serine/threonine kinase 1. (486 aa)
	CD28	CD28 molecule. (220 aa)
	BANK1	B cell scaffold protein with ankyrin repeats 1. (762 aa)
	AXL	AXL receptor tyrosine kinase. (892 aa)
	THEM4	Thioesterase superfamily member 4. (207 aa)
	FLCN	Folliculin. (579 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	PIK3R3	Phosphoinositide-3-kinase regulatory subunit 3. (461 aa)
	TMEM100	Transmembrane protein 100. (134 aa)
	NKX3-1	NK3 homeobox 1. (230 aa)
	DLG1	Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (861 aa)
	GAS6	Growth arrest specific 6. (623 aa)
	IGF1	Insulin like growth factor 1. (208 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (443 aa)
	RPS6KB1	Non-specific serine/threonine protein kinase. (490 aa)
	PIK3C2B	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	PAX2	Paired box 2. (242 aa)
	SMPD3	Sphingomyelin phosphodiesterase 3. (655 aa)
	MT3	Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
	PEAR1	Platelet endothelial aggregation receptor 1. (1037 aa)
	LOX	Lysyl oxidase. (417 aa)
	SIRT2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (364 aa)
	PLK3	Serine/threonine-protein kinase PLK. (647 aa)
	LINGO1	Leucine rich repeat and Ig domain containing 1. (652 aa)
	CD40	CD40 molecule. (278 aa)
	BTN2A2	Uncharacterized protein. (518 aa)
	PTEN	Uncharacterized protein. (555 aa)
	ENSRBIP00000034731	Uncharacterized protein. (95 aa)
	AKT2	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
	SETX	Senataxin. (2655 aa)
	ZFP36L1	Uncharacterized protein. (327 aa)
	TSC2	TSC complex subunit 2. (1805 aa)
	ADTRP	Androgen dependent TFPI regulating protein. (248 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
	EPHA2	EPH receptor A2. (1036 aa)
	MERTK	MER proto-oncogene, tyrosine kinase. (997 aa)
	LOC108527746	Uncharacterized protein. (511 aa)
	C1QTNF12	C1q and TNF related 12. (278 aa)
	TYRO3	TYRO3 protein tyrosine kinase. (893 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKT1	AKT2	ENSRBIP00000010710	ENSRBIP00000034007	AKT serine/threonine kinase 1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.708
AKT1	CD28	ENSRBIP00000010710	ENSRBIP00000012284	AKT serine/threonine kinase 1.	CD28 molecule.	0.438
AKT1	GAS6	ENSRBIP00000010710	ENSRBIP00000005779	AKT serine/threonine kinase 1.	Growth arrest specific 6.	0.432
AKT1	IGF1	ENSRBIP00000010710	ENSRBIP00000008759	AKT serine/threonine kinase 1.	Insulin like growth factor 1.	0.646
AKT1	IL1B	ENSRBIP00000010710	ENSRBIP00000017788	AKT serine/threonine kinase 1.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.583
AKT1	KDR	ENSRBIP00000010710	ENSRBIP00000002621	AKT serine/threonine kinase 1.	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.400
AKT1	PIK3CA	ENSRBIP00000010710	ENSRBIP00000017817	AKT serine/threonine kinase 1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.825
AKT1	PIK3R3	ENSRBIP00000010710	ENSRBIP00000002180	AKT serine/threonine kinase 1.	Phosphoinositide-3-kinase regulatory subunit 3.	0.509
AKT1	PTEN	ENSRBIP00000010710	ENSRBIP00000034962	AKT serine/threonine kinase 1.	Uncharacterized protein.	0.792
AKT1	RPS6KB1	ENSRBIP00000010710	ENSRBIP00000016140	AKT serine/threonine kinase 1.	Non-specific serine/threonine protein kinase.	0.678
AKT1	RPS6KB2	ENSRBIP00000010710	ENSRBIP00000024408	AKT serine/threonine kinase 1.	Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.	0.579
AKT1	TGFB1	ENSRBIP00000010710	ENSRBIP00000006822	AKT serine/threonine kinase 1.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.576
AKT1	THEM4	ENSRBIP00000010710	ENSRBIP00000015750	AKT serine/threonine kinase 1.	Thioesterase superfamily member 4.	0.766
AKT1	TSC2	ENSRBIP00000010710	ENSRBIP00000032391	AKT serine/threonine kinase 1.	TSC complex subunit 2.	0.788
AKT1	ZFP36L1	ENSRBIP00000010710	ENSRBIP00000033500	AKT serine/threonine kinase 1.	Uncharacterized protein.	0.437
AKT2	AKT1	ENSRBIP00000034007	ENSRBIP00000010710	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	AKT serine/threonine kinase 1.	0.708
AKT2	IGF1	ENSRBIP00000034007	ENSRBIP00000008759	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Insulin like growth factor 1.	0.463
AKT2	NKX3-1	ENSRBIP00000034007	ENSRBIP00000005175	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	NK3 homeobox 1.	0.903
AKT2	PIK3CA	ENSRBIP00000034007	ENSRBIP00000017817	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.967
AKT2	PIK3R3	ENSRBIP00000034007	ENSRBIP00000002180	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	Phosphoinositide-3-kinase regulatory subunit 3.	0.948