38 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WNK4	WNK lysine deficient protein kinase 4. (1243 aa)
	SCT	Secretin. (101 aa)
	APOA2	Apolipoprotein A2. (132 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (452 aa)
	OXT	Oxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family. (153 aa)
	ABCG5	ATP binding cassette subfamily G member 5. (651 aa)
	SLC22A5	Solute carrier family 22 member 5. (581 aa)
	DCANP1	Dendritic cell associated nuclear protein. (208 aa)
	GHRL	Ghrelin and obestatin prepropeptide. (117 aa)
	STK39	Serine/threonine kinase 39. (474 aa)
	TFF2	Trefoil factor 2. (129 aa)
	LEP	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
	TRPV1	Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (839 aa)
	AQP1	Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (270 aa)
	OPRK1	Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family. (380 aa)
	CYP8B1	Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (496 aa)
	LPCAT3	Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa)
	HIP1R	Huntingtin interacting protein 1 related. (1068 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (441 aa)
	ENSRBIP00000001234	Uncharacterized protein. (93 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	NEUROG1	Neurogenin 1. (238 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (310 aa)
	PPP3CA-2	Uncharacterized protein. (70 aa)
	NEUROD1	Neurogenic differentiation factor. (356 aa)
	ABCG8	ATP binding cassette subfamily G member 8. (673 aa)
	ENPP7	Ectonucleotide pyrophosphatase/phosphodiesterase 7. (450 aa)
	HAMP	Hepcidin antimicrobial peptide. (84 aa)
	GHSR	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
	EPB41	Erythrocyte membrane protein band 4.1. (865 aa)
	PRAP1	Uncharacterized protein. (154 aa)
	WNK1	WNK lysine deficient protein kinase 1. (2806 aa)
	APOA5	Apolipoprotein A5. (366 aa)
	TYMP	Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (482 aa)
	TACR1	Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
	NR1H2	Nuclear receptor subfamily 1 group H member 2. (461 aa)
	PTGER3	Prostaglandin E receptor 3. (418 aa)
	SPINK1	Serine peptidase inhibitor, Kazal type 1. (79 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCG5	ABCG8	ENSRBIP00000031490	ENSRBIP00000005455	ATP binding cassette subfamily G member 5.	ATP binding cassette subfamily G member 8.	0.999
ABCG5	NR1H2	ENSRBIP00000031490	ENSRBIP00000022722	ATP binding cassette subfamily G member 5.	Nuclear receptor subfamily 1 group H member 2.	0.550
ABCG5	NR1H3	ENSRBIP00000031490	ENSRBIP00000000571	ATP binding cassette subfamily G member 5.	Nuclear receptor subfamily 1 group H member 3.	0.636
ABCG8	ABCG5	ENSRBIP00000005455	ENSRBIP00000031490	ATP binding cassette subfamily G member 8.	ATP binding cassette subfamily G member 5.	0.999
ABCG8	NR1H2	ENSRBIP00000005455	ENSRBIP00000022722	ATP binding cassette subfamily G member 8.	Nuclear receptor subfamily 1 group H member 2.	0.533
ABCG8	NR1H3	ENSRBIP00000005455	ENSRBIP00000000571	ATP binding cassette subfamily G member 8.	Nuclear receptor subfamily 1 group H member 3.	0.563
APOA2	APOA5	ENSRBIP00000017023	ENSRBIP00000015240	Apolipoprotein A2.	Apolipoprotein A5.	0.817
APOA5	APOA2	ENSRBIP00000015240	ENSRBIP00000017023	Apolipoprotein A5.	Apolipoprotein A2.	0.817
GHRL	GHSR	ENSRBIP00000029484	ENSRBIP00000009607	Ghrelin and obestatin prepropeptide.	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.998
GHRL	LEP	ENSRBIP00000029484	ENSRBIP00000041070	Ghrelin and obestatin prepropeptide.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.892
GHRL	NEUROG1	ENSRBIP00000029484	ENSRBIP00000002104	Ghrelin and obestatin prepropeptide.	Neurogenin 1.	0.447
GHRL	OXT	ENSRBIP00000029484	ENSRBIP00000016557	Ghrelin and obestatin prepropeptide.	Oxytocin/neurophysin I prepropeptide; Belongs to the vasopressin/oxytocin family.	0.482
GHRL	PTGER3	ENSRBIP00000029484	ENSRBIP00000022599	Ghrelin and obestatin prepropeptide.	Prostaglandin E receptor 3.	0.710
GHSR	GHRL	ENSRBIP00000009607	ENSRBIP00000029484	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Ghrelin and obestatin prepropeptide.	0.998
GHSR	LEP	ENSRBIP00000009607	ENSRBIP00000041070	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	0.430
LEP	GHRL	ENSRBIP00000041070	ENSRBIP00000029484	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	Ghrelin and obestatin prepropeptide.	0.892
LEP	GHSR	ENSRBIP00000041070	ENSRBIP00000009607	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...]	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.430
NEUROG1	GHRL	ENSRBIP00000002104	ENSRBIP00000029484	Neurogenin 1.	Ghrelin and obestatin prepropeptide.	0.447
NR1H2	ABCG5	ENSRBIP00000022722	ENSRBIP00000031490	Nuclear receptor subfamily 1 group H member 2.	ATP binding cassette subfamily G member 5.	0.550
NR1H2	ABCG8	ENSRBIP00000022722	ENSRBIP00000005455	Nuclear receptor subfamily 1 group H member 2.	ATP binding cassette subfamily G member 8.	0.533