STRINGSTRING
ENPP2 ENPP2 ISM1 ISM1 SERPINE1 SERPINE1 VEGFC VEGFC APLNR APLNR PRKD2 PRKD2 EPN1 EPN1 PDCD10 PDCD10 CELA1 CELA1 HRG HRG ECSCR ECSCR PTGIS PTGIS RUNX1 RUNX1 CXCR3 CXCR3 SFRP2 SFRP2 F3 F3 JAK1 JAK1 FASLG FASLG ANXA3 ANXA3 KDR KDR TGFB2 TGFB2 ENSRBIP00000002994 ENSRBIP00000002994 TIE1 TIE1 KLF4 KLF4 WARS2 WARS2 DCN DCN PAK4 PAK4 ETS1 ETS1 DLL1 DLL1 ANGPT4 ANGPT4 PRKD1 PRKD1 RHOB RHOB CYP1B1 CYP1B1 HGS HGS GPNMB GPNMB PPP1R16B PPP1R16B CXCL8 CXCL8 NINJ1 NINJ1 ISL1 ISL1 TLR3 TLR3 ABL1 ABL1 EGLN1 EGLN1 C3 C3 STAT3 STAT3 HSPG2 HSPG2 ABCC8 ABCC8 ENSRBIP00000008740 ENSRBIP00000008740 ITGB3 ITGB3 HIPK1 HIPK1 VEGFD VEGFD AGO2 AGO2 ADAMTS1 ADAMTS1 TNMD TNMD GHSR GHSR FGF1 FGF1 SPRED1 SPRED1 RECK RECK ACVRL1 ACVRL1 SULF1 SULF1 ERAP1 ERAP1 SIRT1 SIRT1 ROCK1 ROCK1 CLDN5 CLDN5 RHOJ RHOJ FKBPL FKBPL CEACAM1 CEACAM1 SIRT6 SIRT6 CREB3L1 CREB3L1 ECM1 ECM1 CD160 CD160 HSPB1 HSPB1 PIK3CB PIK3CB PTK2B PTK2B ENSRBIP00000013453 ENSRBIP00000013453 DAB2IP DAB2IP ENSRBIP00000014275 ENSRBIP00000014275 ITGB2 ITGB2 CCBE1 CCBE1 THBS2 THBS2 THBS4 THBS4 PIK3R6 PIK3R6 PDPK1 PDPK1 ATP2B4 ATP2B4 PGF PGF BTG1 BTG1 HMOX1 HMOX1 ALOX5 ALOX5 RGCC RGCC LOC108520322 LOC108520322 SMOC2 SMOC2 NPPB NPPB CCR3 CCR3 TERT TERT SFRP1 SFRP1 GPR4 GPR4 NR2E1 NR2E1 KRIT1 KRIT1 SMAD1 SMAD1 AGO1 AGO1 ADM2 ADM2 IL1B IL1B RNH1 RNH1 ITGA5 ITGA5 ENSRBIP00000018405 ENSRBIP00000018405 JUP JUP EPHA2 EPHA2 PDE3B PDE3B GLUL GLUL MDK MDK EMC10 EMC10 RTN4 RTN4 ANGPTL3 ANGPTL3 SEMA5A SEMA5A EMILIN1 EMILIN1 STIM1 STIM1 BMPER BMPER PRKCA PRKCA GRN GRN XBP1 XBP1 SPINK5 SPINK5 HK2 HK2 CXCL13 CXCL13 DDAH1 DDAH1 SYNJ2BP SYNJ2BP SASH1 SASH1 APOH APOH ENSRBIP00000021702 ENSRBIP00000021702 PLXND1 PLXND1 ADGRA2 ADGRA2 PRKCB PRKCB VEGFB VEGFB SEMA3E SEMA3E CHRNA7 CHRNA7 PF4 PF4 NRP1 NRP1 FOXO4 FOXO4 CTNNB1 CTNNB1 TGFBR2 TGFBR2 TSPAN12 TSPAN12 ADAM12 ADAM12 SP100 SP100 HOXA5 HOXA5 PROK1 PROK1 TBXA2R TBXA2R JCAD JCAD NIBAN2 NIBAN2 IL17F IL17F SPHK1 SPHK1 ENSRBIP00000025347 ENSRBIP00000025347 TAFA5 TAFA5 MINAR1 MINAR1 TJP1 TJP1 CYBB CYBB FLT1 FLT1 GDF2 GDF2 SERPINF1 SERPINF1 SEMA4A SEMA4A ITGAX ITGAX COL4A2 COL4A2 PTPRM PTPRM KLF2 KLF2 TEK TEK FUT1 FUT1 NODAL NODAL APELA APELA CXCL10 CXCL10 PLK2 PLK2 GHRL GHRL GATA2 GATA2 COL4A3 COL4A3 STAB1 STAB1 RLN2 RLN2 OR10J5 OR10J5 FGF2 FGF2 GAB1 GAB1 ADGRB1 ADGRB1 CCL24 CCL24 HMGA2 HMGA2 ADGRB2 ADGRB2 JMJD8 JMJD8 ERBB2 ERBB2 E2F2 E2F2 TBC1D31 TBC1D31 EPHA1 EPHA1 HHEX HHEX HIPK2 HIPK2 ENSRBIP00000032954 ENSRBIP00000032954 HTATIP2 HTATIP2 NPR1 NPR1 ENSRBIP00000033334 ENSRBIP00000033334 ENSRBIP00000033881 ENSRBIP00000033881 RAMP2 RAMP2 GATA4 GATA4 NOS3 NOS3 AKT3 AKT3 ITGB8 ITGB8 CDH5 CDH5 ENG ENG CCM2 CCM2 ADAMTS9 ADAMTS9 CTSH CTSH HPSE HPSE LRG1 LRG1 PIK3CD PIK3CD VASH1 VASH1 PML PML VEGFA VEGFA EMILIN2 EMILIN2 CD40 CD40 SP1 SP1 ANGPTL4 ANGPTL4 ZNF304 ZNF304 WARS1 WARS1 ATF2 ATF2 MYDGF MYDGF AGGF1 AGGF1 SLC12A2 SLC12A2 TNN TNN STAT1 STAT1 ENSRBIP00000037030 ENSRBIP00000037030 ENSRBIP00000037067 ENSRBIP00000037067 ZC3H12A ZC3H12A FGF18 FGF18 GTF2I GTF2I FOXJ2 FOXJ2 MAPK7 MAPK7 NFE2L2 NFE2L2 PLCG1 PLCG1 TMIGD2 TMIGD2 GADD45A GADD45A CX3CR1 CX3CR1 MECP2 MECP2 EPN2 EPN2 HIF1A HIF1A C5 C5 MTDH MTDH VASH2 VASH2 CHI3L1 CHI3L1 NTRK1 NTRK1 AMOT AMOT HGF HGF SPARC SPARC ANGPT2 ANGPT2 CNMD CNMD NAXE NAXE LEP LEP WNT5A WNT5A EMP2 EMP2 SEMA6A SEMA6A IL10 IL10 BRCA1 BRCA1 THBS1 THBS1 TNFSF12 TNFSF12 PKM PKM HSPB6 HSPB6 ADM ADM EFNA1 EFNA1 AQP1 AQP1 RRAS RRAS NF1 NF1 ROCK2 ROCK2 HYAL1 HYAL1 CD34 CD34 YJEFN3 YJEFN3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (982 aa)
ISM1Isthmin 1. (464 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (429 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (350 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
EPN1Epsin 1. (662 aa)
PDCD10Programmed cell death 10. (212 aa)
CELA1Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (254 aa)
HRGHistidine rich glycoprotein. (530 aa)
ECSCRUncharacterized protein. (205 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
RUNX1RUNX family transcription factor 1. (264 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
F3Coagulation factor III, tissue factor. (296 aa)
JAK1Tyrosine-protein kinase. (1159 aa)
FASLGFas ligand; Belongs to the tumor necrosis factor family. (280 aa)
ANXA3Annexin. (323 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ENSRBIP00000002994Protein kinase domain-containing protein. (358 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
KLF4Kruppel like factor 4. (511 aa)
WARS2Tryptophanyl tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (360 aa)
DCNDecorin; May affect the rate of fibrils formation. (359 aa)
PAK4Non-specific serine/threonine protein kinase. (593 aa)
ETS1ETS proto-oncogene 1, transcription factor. (485 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (748 aa)
ANGPT4Angiopoietin 4. (503 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (892 aa)
RHOBRas homolog family member B. (196 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
GPNMBGlycoprotein nmb. (561 aa)
PPP1R16BProtein phosphatase 1 regulatory subunit 16B. (567 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
NINJ1Ninjurin 1. (152 aa)
ISL1ISL LIM homeobox 1. (349 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (903 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
EGLN1Egl-9 family hypoxia inducible factor 1. (409 aa)
C3Complement C3. (1598 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
HSPG2Heparan sulfate proteoglycan 2. (4313 aa)
ABCC8ATP binding cassette subfamily C member 8. (1585 aa)
ENSRBIP00000008740tRNA-synt_2b domain-containing protein. (156 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
HIPK1Homeodomain interacting protein kinase 1. (1417 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (879 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (967 aa)
TNMDTenomodulin. (236 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
SPRED1Sprouty related EVH1 domain containing 1. (444 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (963 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (872 aa)
ERAP1Aminopeptidase. (935 aa)
SIRT1Sirtuin 1. (731 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1341 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
RHOJRas homolog family member J. (214 aa)
FKBPLFKBP prolyl isomerase like. (349 aa)
CEACAM1Uncharacterized protein. (525 aa)
SIRT6Sirtuin 6. (355 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (442 aa)
ECM1Extracellular matrix protein 1. (540 aa)
CD160CD160 molecule. (232 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (929 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
ENSRBIP00000013453SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (173 aa)
DAB2IPDAB2 interacting protein. (1156 aa)
ENSRBIP00000014275Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (351 aa)
ITGB2Integrin beta. (779 aa)
CCBE1Collagen and calcium binding EGF domains 1. (376 aa)
THBS2Thrombospondin 2. (1081 aa)
THBS4Thrombospondin 4. (961 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (754 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (351 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
BTG1BTG anti-proliferation factor 1. (171 aa)
HMOX1Heme oxygenase 1. (284 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
RGCCRegulator of cell cycle. (137 aa)
LOC108520322Fork-head domain-containing protein. (198 aa)
SMOC2SPARC related modular calcium binding 2. (394 aa)
NPPBNatriuretic peptide B. (124 aa)
CCR3C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (376 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1167 aa)
SFRP1Secreted frizzled related protein 1. (313 aa)
GPR4G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (344 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
KRIT1Uncharacterized protein. (736 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (857 aa)
ADM2Adrenomedullin 2. (148 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
RNH1Ribonuclease/angiogenin inhibitor 1. (456 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1051 aa)
ENSRBIP00000018405Gln-synt_C domain-containing protein; Belongs to the glutamine synthetase family. (342 aa)
JUPJunction plakoglobin. (709 aa)
EPHA2EPH receptor A2. (1036 aa)
PDE3BPhosphodiesterase. (733 aa)
GLULGlutamine synthetase. (373 aa)
MDKUncharacterized protein. (143 aa)
EMC10ER membrane protein complex subunit 10. (351 aa)
RTN4Reticulon. (1172 aa)
ANGPTL3Angiopoietin like 3. (446 aa)
SEMA5ASemaphorin 5A. (1035 aa)
EMILIN1Elastin microfibril interfacer 1. (620 aa)
STIM1Stromal interaction molecule 1. (791 aa)
BMPERBMP binding endothelial regulator. (685 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
GRNGranulin precursor. (593 aa)
XBP1BZIP domain-containing protein. (380 aa)
SPINK5Serine peptidase inhibitor, Kazal type 5. (1060 aa)
HK2Hexokinase 2. (917 aa)
CXCL13C-X-C motif chemokine. (109 aa)
DDAH1Dimethylarginine dimethylaminohydrolase 1. (285 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
SASH1SAM and SH3 domain containing 1. (1246 aa)
APOHApolipoprotein H. (289 aa)
ENSRBIP00000021702Uncharacterized protein. (144 aa)
PLXND1Plexin D1. (1884 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1324 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (630 aa)
VEGFBVascular endothelial growth factor B. (183 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (741 aa)
CHRNA7Uncharacterized protein. (503 aa)
PF4C-X-C motif chemokine. (101 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
FOXO4Forkhead box O4. (354 aa)
CTNNB1Catenin beta 1. (781 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
TSPAN12Tetraspanin. (305 aa)
ADAM12ADAM metallopeptidase domain 12. (938 aa)
SP100SP100 nuclear antigen. (823 aa)
HOXA5Homeobox A5. (270 aa)
PROK1Prokineticin 1. (105 aa)
TBXA2RThromboxane A2 receptor. (379 aa)
JCADJunctional cadherin 5 associated. (1357 aa)
NIBAN2Niban apoptosis regulator 2. (746 aa)
IL17FInterleukin 17F. (163 aa)
SPHK1Sphingosine kinase 1. (384 aa)
ENSRBIP00000025347SCY domain-containing protein. (90 aa)
TAFA5TAFA chemokine like family member 5. (180 aa)
MINAR1Membrane integral NOTCH2 associated receptor 1. (916 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1737 aa)
CYBBCytochrome b-245 beta chain. (513 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1337 aa)
GDF2Growth differentiation factor 2. (429 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (760 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1172 aa)
COL4A2Collagen type IV alpha 2 chain. (1712 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1496 aa)
KLF2Uncharacterized protein. (194 aa)
TEKTEK receptor tyrosine kinase. (1123 aa)
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (451 aa)
NODALNodal growth differentiation factor. (347 aa)
APELAApelin receptor early endogenous ligand. (54 aa)
CXCL10C-X-C motif chemokine. (98 aa)
PLK2Serine/threonine-protein kinase PLK. (685 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
GATA2GATA binding protein 2. (468 aa)
COL4A3Collagen type IV alpha 3 chain. (1644 aa)
STAB1Stabilin 1. (2537 aa)
RLN2Relaxin 2. (185 aa)
OR10J5Olfactory receptor family 10 subfamily J member 5. (295 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (263 aa)
GAB1GRB2 associated binding protein 1. (722 aa)
ADGRB1Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1548 aa)
CCL24C-C motif chemokine ligand 24. (111 aa)
HMGA2High mobility group AT-hook 2. (147 aa)
ADGRB2Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family. (1587 aa)
JMJD8Jumonji domain containing 8. (277 aa)
ERBB2Receptor protein-tyrosine kinase. (1255 aa)
E2F2E2F transcription factor 2. (437 aa)
TBC1D31Uncharacterized protein. (1067 aa)
EPHA1EPH receptor A1. (963 aa)
HHEXHematopoietically expressed homeobox. (270 aa)
HIPK2Homeodomain interacting protein kinase 2. (1209 aa)
ENSRBIP00000032954Fork-head domain-containing protein. (162 aa)
HTATIP2HIV-1 Tat interactive protein 2. (241 aa)
NPR1Guanylate cyclase. (1061 aa)
ENSRBIP00000033334Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (676 aa)
ENSRBIP00000033881Uncharacterized protein. (61 aa)
RAMP2Receptor activity modifying protein 2. (175 aa)
GATA4GATA binding protein 4. (432 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
AKT3AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (389 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (745 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
ENGEndoglin. (607 aa)
CCM2CCM2 scaffold protein. (466 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1916 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
HPSEHeparanase. (535 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (347 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1044 aa)
VASH1Vasohibin 1. (365 aa)
PMLPromyelocytic leukemia. (932 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (409 aa)
EMILIN2Elastin microfibril interfacer 2. (831 aa)
CD40CD40 molecule. (278 aa)
SP1Sp1 transcription factor. (769 aa)
ANGPTL4Angiopoietin like 4. (368 aa)
ZNF304Zinc finger protein 304. (707 aa)
WARS1Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (475 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (429 aa)
MYDGFMyeloid derived growth factor. (174 aa)
AGGF1Uncharacterized protein. (688 aa)
SLC12A2Solute carrier family 12 member 2. (1210 aa)
TNNTenascin N. (1299 aa)
STAT1Signal transducer and activator of transcription. (787 aa)
ENSRBIP00000037030Uncharacterized protein. (54 aa)
ENSRBIP00000037067Uncharacterized protein. (65 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (570 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
GTF2IGeneral transcription factor IIi. (928 aa)
FOXJ2Forkhead box J2. (574 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (605 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
TMIGD2Transmembrane and immunoglobulin domain containing 2. (302 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (165 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (387 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (498 aa)
EPN2Epsin 2. (641 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (842 aa)
C5Complement C5. (1676 aa)
MTDHMetadherin. (581 aa)
VASH2Vasohibin 2. (355 aa)
CHI3L1Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (405 aa)
NTRK1Tyrosine-protein kinase receptor. (816 aa)
AMOTAngiomotin. (1045 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
SPARCSecreted protein acidic and cysteine rich. (341 aa)
ANGPT2Angiopoietin 2. (510 aa)
CNMDChondromodulin. (334 aa)
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (288 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
IL10Interleukin 10. (178 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1818 aa)
THBS1Thrombospondin 1. (1170 aa)
TNFSF12TNF superfamily member 12; Belongs to the tumor necrosis factor family. (249 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (556 aa)
HSPB6Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family. (160 aa)
ADMAdrenomedullin. (185 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (156 aa)
AQP1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (270 aa)
RRASRAS related. (218 aa)
NF1Neurofibromin 1. (2822 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1387 aa)
HYAL1Hyaluronidase. (435 aa)
CD34CD34 molecule. (385 aa)
YJEFN3YjeF N-terminal domain containing 3. (293 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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