STRINGSTRING
TNR TNR SPAG9 SPAG9 IFRD1 IFRD1 CDKL3 CDKL3 ADRB2 ADRB2 LOC108541626 LOC108541626 MT3 MT3 SEMA6A SEMA6A WNT5A WNT5A SEMA5B SEMA5B PTPRS PTPRS TOMM70 TOMM70 BMP4 BMP4 SEMA3A SEMA3A ULK1 ULK1 GNAS GNAS KCNK2 KCNK2 SEMA6C SEMA6C SAV1 SAV1 MYOZ1 MYOZ1 PTEN PTEN MAPK11 MAPK11 WWC2 WWC2 FGFR3 FGFR3 TRIM46 TRIM46 EPHA7 EPHA7 SLIT1 SLIT1 ULK2 ULK2 BBS2 BBS2 DRAXIN DRAXIN WNT3A WNT3A ANKRD26 ANKRD26 ENSRBIP00000030934 ENSRBIP00000030934 PI16 PI16 LGMN LGMN GDF15 GDF15 SEMA3F SEMA3F NTN1 NTN1 DCC DCC ENSRBIP00000028070 ENSRBIP00000028070 DUSP10 DUSP10 FXN FXN SEMA4A SEMA4A SPART SPART SEMA3D SEMA3D SPP1 SPP1 CDK5 CDK5 FGF13 FGF13 DSPP DSPP TGFBR2 TGFBR2 KIAA0319 KIAA0319 STK3 STK3 NRP1 NRP1 PLXNA3 PLXNA3 RNF6 RNF6 SEMA3E SEMA3E SEMA4D SEMA4D CTDP1 CTDP1 SEMA5A SEMA5A RTN4 RTN4 TBX5 TBX5 SEMA7A SEMA7A RGS2 RGS2 ADRB1 ADRB1 SEMA4C SEMA4C TP73 TP73 NKD1 NKD1 LOC108521987 LOC108521987 SEMA3B SEMA3B SLC6A4 SLC6A4 IFRD2 IFRD2 ARHGAP4 ARHGAP4 WWC1 WWC1 SEMA6B SEMA6B FSTL4 FSTL4 VGLL4 VGLL4 MAG MAG MEIS1 MEIS1 PTCH1 PTCH1 TLL2 TLL2 G6PD G6PD CITED2 CITED2 OSTN OSTN RAI1 RAI1 SOCS2 SOCS2 ENSRBIP00000009112 ENSRBIP00000009112 ENSRBIP00000009022 ENSRBIP00000009022 CDKN1A CDKN1A MAP2 MAP2 ENSRBIP00000007851 ENSRBIP00000007851 PPARA PPARA SEMA4B SEMA4B ENSRBIP00000006659 ENSRBIP00000006659 GSK3A GSK3A RYK RYK PLAC8 PLAC8 JARID2 JARID2 SEMA4G SEMA4G BCL11A BCL11A NOG NOG SEMA4F SEMA4F SEMA3G SEMA3G FOXP1 FOXP1 WNT3 WNT3 MSTN MSTN CAV3 CAV3 DIP2B DIP2B CDKN1B CDKN1B WWC3 WWC3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNRTenascin R. (1358 aa)
SPAG9Sperm associated antigen 9. (1316 aa)
IFRD1Interferon related developmental regulator 1. (451 aa)
CDKL3Cyclin dependent kinase like 3. (572 aa)
ADRB2Adrenoceptor beta 2. (399 aa)
LOC108541626Uncharacterized protein. (246 aa)
MT3Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SEMA5BSemaphorin 5B. (1193 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1739 aa)
TOMM70Translocase of outer mitochondrial membrane 70. (608 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (774 aa)
ULK1Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily. (1044 aa)
GNASGNAS complex locus. (1041 aa)
KCNK2Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (428 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (961 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
MYOZ1Myozenin 1. (299 aa)
PTENUncharacterized protein. (555 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
WWC2WW and C2 domain containing 2. (1221 aa)
FGFR3Fibroblast growth factor receptor. (783 aa)
TRIM46Tripartite motif containing 46. (746 aa)
EPHA7EPH receptor A7. (985 aa)
SLIT1Slit guidance ligand 1. (1533 aa)
ULK2Unc-51 like autophagy activating kinase 2. (593 aa)
BBS2Bardet-Biedl syndrome 2 protein homolog. (717 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (341 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
ANKRD26Ankyrin repeat domain 26. (1667 aa)
ENSRBIP00000030934Protein kinase domain-containing protein. (188 aa)
PI16Peptidase inhibitor 16; Belongs to the CRISP family. (466 aa)
LGMNLegumain. (433 aa)
GDF15Growth differentiation factor 15. (308 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
NTN1Netrin 1. (604 aa)
DCCDCC netrin 1 receptor. (762 aa)
ENSRBIP00000028070Uncharacterized protein. (490 aa)
DUSP10Dual specificity phosphatase 10. (500 aa)
FXNFrataxin. (210 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (760 aa)
SPARTSpartin. (666 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (673 aa)
SPP1Secreted phosphoprotein 1. (314 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
DSPPDentin sialophosphoprotein. (1310 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
KIAA0319KIAA0319. (1031 aa)
STK3Serine/threonine kinase 3. (490 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
PLXNA3Plexin A3. (1876 aa)
RNF6Ring finger protein 6. (701 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (741 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
CTDP1RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (725 aa)
SEMA5ASemaphorin 5A. (1035 aa)
RTN4Reticulon. (1172 aa)
TBX5T-box transcription factor 5. (518 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (668 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
ADRB1Adrenoceptor beta 1; Belongs to the G-protein coupled receptor 1 family. (457 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (636 aa)
NKD1NKD inhibitor of WNT signaling pathway 1. (470 aa)
LOC108521987DUF3496 domain-containing protein. (153 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (754 aa)
SLC6A4Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (630 aa)
IFRD2Uncharacterized protein. (510 aa)
ARHGAP4Rho GTPase activating protein 4. (946 aa)
WWC1WW and C2 domain containing 1. (1112 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (649 aa)
FSTL4Follistatin like 4. (842 aa)
VGLL4Vestigial like family member 4. (296 aa)
MAGMyelin associated glycoprotein. (626 aa)
MEIS1Meis homeobox 1. (398 aa)
PTCH1Patched 1. (1455 aa)
TLL2Metalloendopeptidase. (1015 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (545 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (253 aa)
OSTNOsteocrin. (133 aa)
RAI1Retinoic acid induced 1. (1905 aa)
SOCS2Suppressor of cytokine signaling 2. (233 aa)
ENSRBIP00000009112Uncharacterized protein. (117 aa)
ENSRBIP00000009022CCDC144C domain-containing protein. (348 aa)
CDKN1ACyclin dependent kinase inhibitor 1A. (140 aa)
MAP2Microtubule-associated protein. (1997 aa)
ENSRBIP00000007851ANK_REP_REGION domain-containing protein. (97 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (845 aa)
ENSRBIP00000006659Protein kinase domain-containing protein. (275 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (444 aa)
RYKReceptor like tyrosine kinase. (526 aa)
PLAC8Placenta associated 8. (113 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1246 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (837 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (805 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (231 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (782 aa)
FOXP1Forkhead box P1. (693 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
MSTNMyostatin. (376 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
DIP2BDisco interacting protein 2 homolog B. (1576 aa)
CDKN1BCyclin dependent kinase inhibitor 1B. (198 aa)
WWC3WWC family member 3. (1132 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.