STRINGSTRING
HNF1A HNF1A GPER1 GPER1 BAIAP3 BAIAP3 KCNN4 KCNN4 VPS35 VPS35 IRS2 IRS2 RBP4 RBP4 NR1H4 NR1H4 CAPN10 CAPN10 PARD6A PARD6A FGA FGA OSBP OSBP PLA2G6 PLA2G6 HIF1A HIF1A TMED10 TMED10 ABAT ABAT EXPH5 EXPH5 PFKM PFKM GHRL GHRL SYTL4 SYTL4 TRPM4 TRPM4 VEGFC VEGFC TCF7L2 TCF7L2 CD2AP CD2AP TTN TTN CFTR CFTR ARF6 ARF6 SOX4 SOX4 TRPM2 TRPM2 ACHE ACHE TREM2 TREM2 NR0B2 NR0B2 MCU MCU SRI SRI EXOC1 EXOC1 PPARD PPARD SLC30A8 SLC30A8 PCK2 PCK2 FGG FGG PSMD9 PSMD9 DOC2B DOC2B C2CD2L C2CD2L GIP GIP STX4 STX4 NLGN2 NLGN2 FRMD4A FRMD4A LOC108528963 LOC108528963 PDX1 PDX1 RPH3AL RPH3AL RFX6 RFX6 GCG GCG TGFB3 TGFB3 EZR EZR APBB1 APBB1 LRRC8A LRRC8A ADORA2A ADORA2A GPLD1 GPLD1 MPC2 MPC2 DNM1L DNM1L ADCY8 ADCY8 NR1H2 NR1H2 FGB FGB MYH10 MYH10 GCK GCK TRH TRH MYOM1 MYOM1 C1QTNF12 C1QTNF12 C1QTNF3 C1QTNF3 WLS WLS ADAM8 ADAM8 PTPN23 PTPN23 GOLPH3L GOLPH3L PRKCE PRKCE ENSRBIP00000040815 ENSRBIP00000040815 SEC24A SEC24A VSNL1 VSNL1 MYO18A MYO18A BLK BLK BAD BAD GIPR GIPR GOLPH3 GOLPH3 PPP3CB PPP3CB TUNAR TUNAR TGFB2 TGFB2 ANO1 ANO1 ANKRD1 ANKRD1 MYRIP MYRIP TLR4 TLR4 TGFB1 TGFB1 CASR CASR PLA2G1B PLA2G1B GPR68 GPR68 ABCG1 ABCG1 ISL1 ISL1 TM7SF3 TM7SF3 APBB3 APBB3 ADAM9 ADAM9 PCSK1 PCSK1 IGF1 IGF1 PPID PPID IER3IP1 IER3IP1 P2RX7 P2RX7 SIRT6 SIRT6 ENSRBIP00000011851 ENSRBIP00000011851 ENSRBIP00000011968 ENSRBIP00000011968 FFAR1 FFAR1 CD33 CD33 NNAT NNAT HMMR HMMR BSG BSG ATP13A2 ATP13A2 BMP6 BMP6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HNF1AHNF1 homeobox A. (662 aa)
GPER1G protein-coupled estrogen receptor 1. (373 aa)
BAIAP3BAI1 associated protein 3. (1186 aa)
KCNN4Potassium calcium-activated channel subfamily N member 4. (427 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (778 aa)
IRS2Insulin receptor substrate 2. (904 aa)
RBP4Retinol-binding protein; Retinol-binding protein that mediates retinol transport in blood plasma. (201 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (481 aa)
CAPN10Calpain 10; Belongs to the peptidase C2 family. (672 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
FGAFibrinogen alpha chain. (906 aa)
OSBPOxysterol-binding protein; Belongs to the OSBP family. (791 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (842 aa)
TMED10Transmembrane p24 trafficking protein 10. (219 aa)
ABAT4-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (506 aa)
EXPH5Exophilin 5. (1964 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
SYTL4Synaptotagmin like 4. (672 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1052 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (350 aa)
TCF7L2HMG box domain-containing protein. (376 aa)
CD2APCD2 associated protein. (625 aa)
TTNUncharacterized protein. (563 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
SOX4Transcription factor SOX. (475 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1552 aa)
ACHECarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (631 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (231 aa)
NR0B2Nuclear receptor subfamily 0 group B member 2. (257 aa)
MCUMitochondrial calcium uniporter. (351 aa)
SRISorcin. (198 aa)
EXOC1Exocyst complex component 1. (919 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
SLC30A8Solute carrier family 30 member 8. (369 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
FGGFibrinogen gamma chain. (453 aa)
PSMD9PDZ domain-containing protein. (223 aa)
DOC2BDouble C2-like domain-containing protein. (406 aa)
C2CD2LC2CD2 like. (707 aa)
GIPGastric inhibitory polypeptide. (151 aa)
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
NLGN2Neuroligin 2. (698 aa)
FRMD4AFERM domain containing 4A. (1083 aa)
LOC108528963ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (791 aa)
PDX1Pancreatic and duodenal homeobox 1. (284 aa)
RPH3ALRabphilin 3A like (without C2 domains). (311 aa)
RFX6Regulatory factor X6. (916 aa)
GCGGlucagon. (180 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
EZREzrin. (588 aa)
APBB1Amyloid beta precursor protein binding family B member 1. (746 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (810 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (847 aa)
MPC2Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (127 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (802 aa)
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
FGBFibrinogen beta chain. (491 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1941 aa)
GCKPhosphotransferase. (466 aa)
TRHPro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (242 aa)
MYOM1Myomesin 1. (1672 aa)
C1QTNF12C1q and TNF related 12. (278 aa)
C1QTNF3C1q domain-containing protein. (263 aa)
WLSWnt ligand secretion mediator. (543 aa)
ADAM8ADAM metallopeptidase domain 8. (755 aa)
PTPN23Protein tyrosine phosphatase non-receptor type 23. (1631 aa)
GOLPH3LGolgi phosphoprotein 3 like. (285 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
ENSRBIP00000040815Uncharacterized protein. (5512 aa)
SEC24ASEC24 homolog A, COPII coat complex component. (986 aa)
VSNL1Visinin like 1. (191 aa)
MYO18AMyosin XVIIIA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2212 aa)
BLKTyrosine-protein kinase. (505 aa)
BADBCL2 associated agonist of cell death. (167 aa)
GIPRGastric inhibitory polypeptide receptor; Belongs to the G-protein coupled receptor 2 family. (466 aa)
GOLPH3Golgi phosphoprotein 3. (298 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
TUNARTCL1 upstream neural differentiation-associated RNA. (48 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ANO1Anoctamin. (962 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
MYRIPMyosin VIIA and Rab interacting protein. (859 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
CASRCalcium sensing receptor. (1078 aa)
PLA2G1BPhospholipase A(2). (148 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (375 aa)
ABCG1ATP binding cassette subfamily G member 1. (676 aa)
ISL1ISL LIM homeobox 1. (349 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
APBB3Amyloid beta precursor protein binding family B member 3. (569 aa)
ADAM9ADAM metallopeptidase domain 9. (819 aa)
PCSK1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (749 aa)
IGF1Insulin like growth factor 1. (208 aa)
PPIDPeptidylprolyl isomerase D. (370 aa)
IER3IP1Immediate early response 3 interacting protein 1. (82 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
SIRT6Sirtuin 6. (355 aa)
ENSRBIP00000011851Uncharacterized protein. (107 aa)
ENSRBIP00000011968GOLD domain-containing protein; Belongs to the EMP24/GP25L family. (189 aa)
FFAR1Free fatty acid receptor 1. (300 aa)
CD33CD33 molecule. (499 aa)
NNATNeuronatin. (80 aa)
HMMRHyaluronan mediated motility receptor. (396 aa)
BSGBasigin (Ok blood group). (385 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1189 aa)
BMP6Bone morphogenetic protein 6. (440 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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