STRINGSTRING
GHRL GHRL SYK SYK SIRPA SIRPA FFAR4 FFAR4 TNFRSF1B TNFRSF1B ADORA2A ADORA2A CYLD CYLD GIT1 GIT1 ELANE ELANE RABGEF1 RABGEF1 SERPINF1 SERPINF1 ACP5 ACP5 ENSRBIP00000042716 ENSRBIP00000042716 FOXF1 FOXF1 CYP19A1 CYP19A1 IL10 IL10 PTPRC PTPRC HGF HGF IL4 IL4 ENSRBIP00000039905 ENSRBIP00000039905 TNFRSF1A TNFRSF1A PLCG1 PLCG1 MAPK7 MAPK7 IL2 IL2 FNDC4 FNDC4 LPCAT3 LPCAT3 PPARG PPARG ENSRBIP00000036977 ENSRBIP00000036977 NLRC3 NLRC3 TNFAIP6 TNFAIP6 SLAMF8 SLAMF8 LYN LYN MVK MVK MEFV MEFV PPARD PPARD LOC108535852 LOC108535852 SHARPIN SHARPIN PSMB4 PSMB4 PGLYRP1 PGLYRP1 APCS APCS NR1D1 NR1D1 PROC PROC CDH5 CDH5 SYT11 SYT11 ENSRBIP00000033881 ENSRBIP00000033881 IL22RA2 IL22RA2 LOC108516810 LOC108516810 YES1 YES1 TAFA3 TAFA3 SMPDL3B SMPDL3B FGR FGR ASH1L ASH1L PBK PBK WFDC1 WFDC1 PTPN2 PTPN2 MKRN2 MKRN2 METRNL METRNL ZFP36 ZFP36 GPR17 GPR17 CALCRL CALCRL TEK TEK CD200R1 CD200R1 CST7 CST7 TREM2 TREM2 PSMA1 PSMA1 DUSP10 DUSP10 NT5E NT5E NLRX1 NLRX1 SIGLEC10 SIGLEC10 FURIN FURIN PRKCD PRKCD ENSRBIP00000021702 ENSRBIP00000021702 APOE APOE CX3CL1 CX3CL1 GRN GRN AOAH AOAH CCN3 CCN3 IL20RB IL20RB TNFAIP3 TNFAIP3 C1QTNF12 C1QTNF12 CXCL17 CXCL17 FOXP3 FOXP3 RB1 RB1 C1QTNF3 C1QTNF3 MDK MDK LDLR LDLR ACOD1 ACOD1 KRT1 KRT1 NLRP6 NLRP6 NR1H4 NR1H4 PPARG-2 PPARG-2 NR1D2 NR1D2 VPS35 VPS35 ALOX5 ALOX5 NDFIP1 NDFIP1 ADA ADA MFHAS1 MFHAS1 GPER1 GPER1 GATA3 GATA3 SELENOS SELENOS SOCS3 SOCS3 SOCS5 SOCS5 ENPP3 ENPP3 NFKB1 NFKB1 ADIPOQ ADIPOQ TYRO3 TYRO3 BCR BCR ENSRBIP00000009622 ENSRBIP00000009622 GHSR GHSR IL13 IL13 FEM1A FEM1A IGF1 IGF1 PTGER4 PTGER4 RHBDF2 RHBDF2 IER3 IER3 PPARA PPARA ENSRBIP00000007353 ENSRBIP00000007353 ENSRBIP00000007280 ENSRBIP00000007280 ISL1 ISL1 MMP26 MMP26 NLRP3 NLRP3 SMAD3 SMAD3 FYN FYN HAMP HAMP RORA RORA GPS2 GPS2 LOC108514958 LOC108514958 C5orf30 C5orf30 GPR31 GPR31 KLF4 KLF4 LOC108535814 LOC108535814 OTULIN OTULIN NOD2 NOD2 SRC SRC PTGIS PTGIS LRFN5 LRFN5 NR1H3 NR1H3 ENSRBIP00000000223 ENSRBIP00000000223 NLRP12 NLRP12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GHRLGhrelin and obestatin prepropeptide. (117 aa)
SYKUncharacterized protein. (331 aa)
SIRPAUncharacterized protein. (505 aa)
FFAR4Free fatty acid receptor 4. (377 aa)
TNFRSF1BTNF receptor superfamily member 1B. (462 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (412 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (948 aa)
GIT1GIT ArfGAP 1. (817 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (265 aa)
RABGEF1Uncharacterized protein. (430 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (418 aa)
ACP5Tartrate-resistant acid phosphatase type 5. (325 aa)
ENSRBIP00000042716A_deaminase domain-containing protein. (344 aa)
FOXF1Forkhead box F1. (380 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)
IL10Interleukin 10. (178 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1310 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (728 aa)
IL4Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa)
ENSRBIP00000039905VPS9 domain-containing protein. (259 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
FNDC4Fibronectin type III domain containing 4. (267 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (298 aa)
ENSRBIP00000036977Protein kinase domain-containing protein. (68 aa)
NLRC3NLR family CARD domain containing 3. (1091 aa)
TNFAIP6TNF alpha induced protein 6. (226 aa)
SLAMF8SLAM family member 8. (285 aa)
LYNTyrosine-protein kinase. (512 aa)
MVKMevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa)
MEFVMEFV innate immuity regulator, pyrin. (784 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
LOC108535852Uncharacterized protein. (486 aa)
SHARPINSHANK associated RH domain interactor. (384 aa)
PSMB4Proteasome subunit beta; Belongs to the peptidase T1B family. (274 aa)
PGLYRP1Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (196 aa)
APCSPentaxin. (223 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (613 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa; Belongs to the peptidase S1 family. (476 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
SYT11Synaptotagmin 11. (431 aa)
ENSRBIP00000033881Uncharacterized protein. (61 aa)
IL22RA2Interleukin 22 receptor subunit alpha 2. (257 aa)
LOC108516810Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (330 aa)
YES1Tyrosine-protein kinase. (480 aa)
TAFA3TAFA chemokine like family member 3. (169 aa)
SMPDL3BSphingomyelin phosphodiesterase acid like 3B. (353 aa)
FGRTyrosine-protein kinase. (529 aa)
ASH1LASH1 like histone lysine methyltransferase. (2894 aa)
PBKProtein kinase domain-containing protein. (322 aa)
WFDC1WAP four-disulfide core domain 1. (220 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (387 aa)
MKRN2Makorin ring finger protein 2. (416 aa)
METRNLMeteorin like, glial cell differentiation regulator. (254 aa)
ZFP36ZFP36 ring finger protein. (332 aa)
GPR17G protein-coupled receptor 17; Belongs to the G-protein coupled receptor 1 family. (371 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (461 aa)
TEKTEK receptor tyrosine kinase. (1123 aa)
CD200R1CD200 receptor 1. (348 aa)
CST7Cystatin F. (167 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (231 aa)
PSMA1Proteasome subunit alpha type. (269 aa)
DUSP10Dual specificity phosphatase 10. (500 aa)
NT5E5'-nucleotidase ecto; Belongs to the 5'-nucleotidase family. (574 aa)
NLRX1NLR family member X1. (972 aa)
SIGLEC10Sialic acid binding Ig like lectin 10. (572 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (787 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ENSRBIP00000021702Uncharacterized protein. (144 aa)
APOEApolipoprotein E. (317 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (407 aa)
GRNGranulin precursor. (593 aa)
AOAHAcyloxyacyl hydrolase. (687 aa)
CCN3Cellular communication network factor 3. (357 aa)
IL20RBInterleukin 20 receptor subunit beta. (311 aa)
TNFAIP3TNF alpha induced protein 3. (790 aa)
C1QTNF12C1q and TNF related 12. (278 aa)
CXCL17C-X-C motif chemokine ligand 17. (119 aa)
FOXP3Forkhead box P3. (456 aa)
RB1RB transcriptional corepressor 1. (815 aa)
C1QTNF3C1q domain-containing protein. (263 aa)
MDKUncharacterized protein. (143 aa)
LDLRLow density lipoprotein receptor. (819 aa)
ACOD1Aconitate decarboxylase 1. (458 aa)
KRT1Keratin 1; Belongs to the intermediate filament family. (642 aa)
NLRP6NLR family pyrin domain containing 6. (1041 aa)
NR1H4Nuclear receptor subfamily 1 group H member 4. (481 aa)
PPARG-2Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (217 aa)
NR1D2Nuclear receptor subfamily 1 group D member 2. (579 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (778 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
NDFIP1Nedd4 family interacting protein 1. (221 aa)
ADAA_deaminase domain-containing protein. (443 aa)
MFHAS1Malignant fibrous histiocytoma amplified sequence 1. (1046 aa)
GPER1G protein-coupled estrogen receptor 1. (373 aa)
GATA3GATA binding protein 3. (444 aa)
SELENOSSelenoprotein S. (210 aa)
SOCS3Uncharacterized protein. (225 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
ENPP3Ectonucleotide pyrophosphatase/phosphodiesterase 3. (886 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (275 aa)
TYRO3TYRO3 protein tyrosine kinase. (893 aa)
BCRBCR activator of RhoGEF and GTPase. (1089 aa)
ENSRBIP00000009622Uncharacterized protein. (329 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
IL13Interleukin 13. (146 aa)
FEM1AFem-1 homolog A. (664 aa)
IGF1Insulin like growth factor 1. (208 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (490 aa)
RHBDF2Rhomboid 5 homolog 2. (891 aa)
IER3Immediate early response 3. (156 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
ENSRBIP00000007353A20-type domain-containing protein. (128 aa)
ENSRBIP00000007280Tyrosine-protein phosphatase non-receptor type. (354 aa)
ISL1ISL LIM homeobox 1. (349 aa)
MMP26Matrix metallopeptidase 26. (261 aa)
NLRP3NLR family pyrin domain containing 3. (1035 aa)
SMAD3Mothers against decapentaplegic homolog. (480 aa)
FYNTyrosine-protein kinase. (537 aa)
HAMPHepcidin antimicrobial peptide. (84 aa)
RORARAR related orphan receptor A. (555 aa)
GPS2G protein pathway suppressor 2. (327 aa)
LOC108514958Protein kinase domain-containing protein. (323 aa)
C5orf30Chromosome 5 open reading frame 30. (206 aa)
GPR31G protein-coupled receptor 31; Belongs to the G-protein coupled receptor 1 family. (361 aa)
KLF4Kruppel like factor 4. (511 aa)
LOC108535814Uncharacterized protein. (666 aa)
OTULINOTU deubiquitinase with linear linkage specificity. (352 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1153 aa)
SRCTyrosine-protein kinase. (627 aa)
PTGISProstacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
LRFN5Leucine rich repeat and fibronectin type III domain containing 5. (719 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (441 aa)
ENSRBIP00000000223Proteasome endopeptidase complex. (207 aa)
NLRP12NLR family pyrin domain containing 12. (1055 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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