STRINGSTRING
STUB1 STUB1 RAD18 RAD18 UHRF2-2 UHRF2-2 CNOT4 CNOT4 BRCA1 BRCA1 WWP2 WWP2 BARD1 BARD1 OBI1 OBI1 RNFT1 RNFT1 RCHY1 RCHY1 UBE2A UBE2A CBL CBL TRIM37 TRIM37 RNF157 RNF157 ASB4 ASB4 TRAF6 TRAF6 MARCHF5 MARCHF5 UBE3A UBE3A RNF13 RNF13 DTX3L DTX3L RAD51 RAD51 ENSRBIP00000031796 ENSRBIP00000031796 ENSRBIP00000031768 ENSRBIP00000031768 TRIM52 TRIM52 UBE2B UBE2B TRAF2 TRAF2 RNF11 RNF11 UHRF2 UHRF2 TRIM68 TRIM68 RNF115 RNF115 RNF41 RNF41 SH3RF1 SH3RF1 UBE2T UBE2T AMFR AMFR RNF181 RNF181 LRSAM1 LRSAM1 SH3RF2 SH3RF2 ERCC8 ERCC8 NFX1 NFX1 DDB2 DDB2 SH3RF3 SH3RF3 ITCH ITCH KLHL24 KLHL24 TRIM13 TRIM13 RNF122 RNF122 LOC108523192 LOC108523192 MARCHF7 MARCHF7 ENSRBIP00000021181 ENSRBIP00000021181 RNF220 RNF220 RNF112 RNF112 UHRF1 UHRF1 TRIM71 TRIM71 RNF213 RNF213 RNF185 RNF185 CUL3 CUL3 RNF10 RNF10 PRKN PRKN RNF4 RNF4 ENSRBIP00000006958 ENSRBIP00000006958 RNF19B RNF19B TRIM21 TRIM21 RNF187 RNF187 RAG1 RAG1 ENSRBIP00000005558 ENSRBIP00000005558 LTN1 LTN1 TRIM17 TRIM17 RNF186 RNF186 TRIM58 TRIM58 HECTD1 HECTD1 JADE2 JADE2 BFAR BFAR RNF146 RNF146 RNF141 RNF141 RNF208 RNF208 BRCA2 BRCA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
RAD18RAD18 E3 ubiquitin protein ligase. (494 aa)
UHRF2-2Ubiquitin-like domain-containing protein. (137 aa)
CNOT4CCR4-NOT transcription complex subunit 4. (713 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1818 aa)
WWP2E3 ubiquitin-protein ligase. (870 aa)
BARD1BRCA1 associated RING domain 1. (771 aa)
OBI1ORC ubiquitin ligase 1. (716 aa)
RNFT1Ring finger protein, transmembrane 1. (435 aa)
RCHY1Ring finger and CHY zinc finger domain containing 1. (261 aa)
UBE2AUBIQUITIN_CONJUGAT_2 domain-containing protein. (63 aa)
CBLCbl proto-oncogene. (802 aa)
TRIM37Tripartite motif containing 37. (951 aa)
RNF157Ring finger protein 157. (669 aa)
ASB4Ankyrin repeat and SOCS box containing 4. (426 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
MARCHF5Membrane associated ring-CH-type finger 5. (276 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (877 aa)
RNF13Ring finger protein 13. (381 aa)
DTX3LDeltex E3 ubiquitin ligase 3L. (744 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (337 aa)
ENSRBIP00000031796HECT domain-containing protein. (669 aa)
ENSRBIP00000031768Uncharacterized protein. (245 aa)
TRIM52Tripartite motif containing 52. (279 aa)
UBE2BUbiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (157 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
RNF11Ring finger protein 11. (154 aa)
UHRF2Ubiquitin like with PHD and ring finger domains 2. (674 aa)
TRIM68Uncharacterized protein. (485 aa)
RNF115Ring finger protein 115. (304 aa)
RNF41Ring finger protein 41. (317 aa)
SH3RF1SH3 domain containing ring finger 1. (889 aa)
UBE2TUbiquitin conjugating enzyme E2 T; Belongs to the ubiquitin-conjugating enzyme family. (240 aa)
AMFRAutocrine motility factor receptor. (645 aa)
RNF181Ring finger protein 181. (153 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (634 aa)
SH3RF2SH3 domain containing ring finger 2. (729 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (370 aa)
NFX1Nuclear transcription factor, X-box binding 1. (1043 aa)
DDB2Damage specific DNA binding protein 2. (427 aa)
SH3RF3SH3 domain containing ring finger 3. (599 aa)
ITCHE3 ubiquitin-protein ligase. (862 aa)
KLHL24Kelch like family member 24. (600 aa)
TRIM13Tripartite motif containing 13. (410 aa)
RNF122Ring finger protein 122. (155 aa)
LOC108523192UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (101 aa)
MARCHF7Membrane associated ring-CH-type finger 7. (704 aa)
ENSRBIP00000021181YDG domain-containing protein. (705 aa)
RNF220RNF220 domain-containing protein. (234 aa)
RNF112Ring finger protein 112. (753 aa)
UHRF1Ubiquitin like with PHD and ring finger domains 1. (859 aa)
TRIM71Tripartite motif containing 71. (749 aa)
RNF213Ring finger protein 213. (5215 aa)
RNF185Ring finger protein 185. (195 aa)
CUL3Cullin 3; Belongs to the cullin family. (715 aa)
RNF10Ring finger protein 10. (810 aa)
PRKNE3 ubiquitin-protein ligase parkin; Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins; Belongs to the RBR family. Parkin subfamily. (465 aa)
RNF4Ring finger protein 4. (190 aa)
ENSRBIP00000006958TNF receptor-associated factor. (473 aa)
RNF19BRBR-type E3 ubiquitin transferase. (700 aa)
TRIM21Tripartite motif containing 21. (475 aa)
RNF187Ring finger protein 187. (141 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa)
ENSRBIP00000005558Uncharacterized protein. (421 aa)
LTN1Listerin E3 ubiquitin protein ligase 1. (1774 aa)
TRIM17Tripartite motif containing 17. (477 aa)
RNF186Ring finger protein 186. (224 aa)
TRIM58Tripartite motif containing 58. (478 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2472 aa)
JADE2Jade family PHD finger 2. (834 aa)
BFARBifunctional apoptosis regulator. (450 aa)
RNF146Ring finger protein 146. (360 aa)
RNF141Ring finger protein 141. (230 aa)
RNF208RING-type domain-containing protein. (261 aa)
BRCA2Uncharacterized protein. (386 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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