STRINGSTRING
LOC108525471 LOC108525471 AHI1 AHI1 HIP1R HIP1R SPDEF SPDEF ENSRBIP00000000681 ENSRBIP00000000681 CELA1 CELA1 BBS7 BBS7 FGF10 FGF10 HOXA13 HOXA13 SRC SRC NKX3-2 NKX3-2 SFRP2 SFRP2 HLX HLX TGFB2 TGFB2 PKD1 PKD1 OVOL2 OVOL2 SALL1 SALL1 FOXL1 FOXL1 FZD5 FZD5 ENSRBIP00000005056 ENSRBIP00000005056 SMAD3 SMAD3 CXCL8 CXCL8 TGFB1 TGFB1 FOXE1 FOXE1 KLF5 KLF5 TIGAR TIGAR COL3A1 COL3A1 EPB41L5 EPB41L5 PRDM1 PRDM1 TP63 TP63 EPHB3 EPHB3 BCL2 BCL2 ASCL1 ASCL1 DACT1 DACT1 LOC108522026 LOC108522026 SHH SHH PYY PYY RARB RARB PTK6 PTK6 SMAD2 SMAD2 MEGF8 MEGF8 ZIC3 ZIC3 PDGFC PDGFC NKX2-2 NKX2-2 CLMP CLMP FGFR2 FGFR2 ADA ADA CCDC103 CCDC103 DCHS1 DCHS1 CCKBR CCKBR SOX10 SOX10 ENSRBIP00000016233 ENSRBIP00000016233 C6orf58 C6orf58 SFRP1 SFRP1 ENSRBIP00000016589 ENSRBIP00000016589 ALDH1A2 ALDH1A2 ENSRBIP00000017044 ENSRBIP00000017044 SCT SCT HMGCS2 HMGCS2 TCF21 TCF21 PKDCC PKDCC WDR19 WDR19 HOXD13 HOXD13 DNAAF1 DNAAF1 RB1 RB1 MIXL1 MIXL1 EDNRB EDNRB CPS1 CPS1 PTF1A PTF1A TBX2 TBX2 NOTCH1 NOTCH1 VPS52 VPS52 CTNNB1 CTNNB1 COBL COBL TGFBR2 TGFBR2 HOXA5 HOXA5 YAP1 YAP1 ASS1 ASS1 TGFB3 TGFB3 MYOCD MYOCD STRA6 STRA6 AGR2 AGR2 OTC OTC GLI3 GLI3 ENSRBIP00000027977 ENSRBIP00000027977 ALX4 ALX4 RET RET KIT KIT ACVR2B ACVR2B NODAL NODAL CCDC39 CCDC39 CRKL CRKL CDX2 CDX2 ENSRBIP00000029611 ENSRBIP00000029611 NKX2-3 NKX2-3 YIPF6 YIPF6 FGF9 FGF9 IL6ST IL6ST CHD8 CHD8 PDX1 PDX1 ENSRBIP00000031047 ENSRBIP00000031047 PCSK5 PCSK5 GIP GIP CLDN18 CLDN18 SOX17 SOX17 FOXF2 FOXF2 GATA4 GATA4 TYMS TYMS WDPCP WDPCP GLI1 GLI1 IHH IHH NKX2-6 NKX2-6 SIX2 SIX2 SAV1 SAV1 ENSRBIP00000036079 ENSRBIP00000036079 EXT1 EXT1 C1GALT1 C1GALT1 LGR4 LGR4 WNT11 WNT11 IGF2 IGF2 HIF1A HIF1A BMP4 BMP4 GATA5 GATA5 IFT172 IFT172 ENSRBIP00000040023 ENSRBIP00000040023 CBFA2T2 CBFA2T2 WNT5A WNT5A CCDC40 CCDC40 SMO SMO KCNQ1 KCNQ1 BARX1 BARX1 NIPBL NIPBL SHOX2 SHOX2 FOXF1 FOXF1 ENSRBIP00000042716 ENSRBIP00000042716 ID2 ID2 GLI2 GLI2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108525471Uncharacterized protein. (356 aa)
AHI1Abelson helper integration site 1. (1195 aa)
HIP1RHuntingtin interacting protein 1 related. (1068 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (335 aa)
ENSRBIP00000000681Uncharacterized protein. (453 aa)
CELA1Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (254 aa)
BBS7Bardet-Biedl syndrome 7. (714 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
HOXA13Homeobox domain-containing protein. (214 aa)
SRCTyrosine-protein kinase. (627 aa)
NKX3-2NK3 homeobox 2. (333 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
HLXH2.0 like homeobox. (494 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4129 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
SALL1Spalt like transcription factor 1. (1224 aa)
FOXL1Forkhead box L1. (345 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
ENSRBIP00000005056Uncharacterized protein. (199 aa)
SMAD3Mothers against decapentaplegic homolog. (480 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
FOXE1Forkhead box E1. (337 aa)
KLF5Kruppel like factor 5. (442 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (316 aa)
COL3A1Collagen type III alpha 1 chain. (1333 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (716 aa)
PRDM1PR/SET domain 1. (825 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
EPHB3EPH receptor B3. (1008 aa)
BCL2BCL2 apoptosis regulator. (239 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (234 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (837 aa)
LOC108522026C2H2-type domain-containing protein. (418 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (427 aa)
PYYPeptide YY. (97 aa)
RARBRetinoic acid receptor beta. (448 aa)
PTK6Tyrosine-protein kinase. (451 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
MEGF8Multiple EGF like domains 8. (2767 aa)
ZIC3Zic family member 3. (466 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
NKX2-2NK2 homeobox 2. (273 aa)
CLMPCXADR like membrane protein. (395 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
ADAA_deaminase domain-containing protein. (443 aa)
CCDC103Coiled-coil domain containing 103. (242 aa)
DCHS1Dachsous cadherin-related 1. (3295 aa)
CCKBRCholecystokinin B receptor; Belongs to the G-protein coupled receptor 1 family. (450 aa)
SOX10SRY-box transcription factor 10. (466 aa)
ENSRBIP00000016233Uncharacterized protein. (371 aa)
C6orf58Chromosome 6 open reading frame 58. (330 aa)
SFRP1Secreted frizzled related protein 1. (313 aa)
ENSRBIP00000016589Uncharacterized protein. (267 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
ENSRBIP00000017044Uncharacterized protein. (392 aa)
SCTSecretin. (101 aa)
HMGCS23-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (508 aa)
TCF21Transcription factor 21. (179 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (277 aa)
WDR19WD repeat domain 19. (1307 aa)
HOXD13Homeobox D13. (342 aa)
DNAAF1Dynein assembly factor 1, axonemal. (725 aa)
RB1RB transcriptional corepressor 1. (815 aa)
MIXL1Mix paired-like homeobox. (211 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (507 aa)
CPS1Carbamoyl-phosphate synthase 1. (1433 aa)
PTF1APancreas associated transcription factor 1a. (329 aa)
TBX2T-box transcription factor 2. (686 aa)
NOTCH1Notch receptor 1. (2438 aa)
VPS52VPS52 subunit of GARP complex. (723 aa)
CTNNB1Catenin beta 1. (781 aa)
COBLCordon-bleu WH2 repeat protein. (1317 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
HOXA5Homeobox A5. (270 aa)
YAP1Yes associated protein 1. (326 aa)
ASS1Uncharacterized protein. (412 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
MYOCDMyocardin. (832 aa)
STRA6Stimulated by retinoic acid 6. (706 aa)
AGR2Anterior gradient 2, protein disulphide isomerase family member. (175 aa)
OTCOrnithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (324 aa)
GLI3GLI family zinc finger 3. (1555 aa)
ENSRBIP00000027977Uncharacterized protein. (413 aa)
ALX4ALX homeobox 4. (409 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1099 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (972 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
NODALNodal growth differentiation factor. (347 aa)
CCDC39Coiled-coil domain containing 39. (915 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
CDX2Caudal type homeobox 2. (313 aa)
ENSRBIP00000029611Uncharacterized protein. (103 aa)
NKX2-3NK2 homeobox 3. (365 aa)
YIPF6Protein YIPF. (193 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
IL6STUncharacterized protein. (330 aa)
CHD8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2535 aa)
PDX1Pancreatic and duodenal homeobox 1. (284 aa)
ENSRBIP00000031047Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (365 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1860 aa)
GIPGastric inhibitory polypeptide. (151 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
SOX17SRY-box transcription factor 17. (412 aa)
FOXF2Forkhead box F2. (382 aa)
GATA4GATA binding protein 4. (432 aa)
TYMSThymidylate synthetase. (313 aa)
WDPCPWD repeat containing planar cell polarity effector. (581 aa)
GLI1GLI family zinc finger 1. (1106 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
NKX2-6NK2 homeobox 6. (301 aa)
SIX2SIX homeobox 2. (292 aa)
SAV1Salvador family WW domain containing protein 1. (384 aa)
ENSRBIP00000036079Uncharacterized protein. (375 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
C1GALT1Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (371 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (931 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
IGF2Insulin like growth factor 2. (236 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (842 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
GATA5GATA binding protein 5. (263 aa)
IFT172Intraflagellar transport 172. (1753 aa)
ENSRBIP00000040023Uncharacterized protein. (103 aa)
CBFA2T2CBFA2/RUNX1 partner transcriptional co-repressor 2. (614 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
CCDC40Coiled-coil domain containing 40. (1145 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (786 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (452 aa)
BARX1BARX homeobox 1. (250 aa)
NIPBLNipped-B protein. (2777 aa)
SHOX2Short stature homeobox 2. (355 aa)
FOXF1Forkhead box F1. (380 aa)
ENSRBIP00000042716A_deaminase domain-containing protein. (344 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
GLI2GLI family zinc finger 2. (1581 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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