(17 nodes) Definitive hemopoiesis network (Rhinopithecus bieti)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MEIS1	Meis homeobox 1. (398 aa)
	TEK	TEK receptor tyrosine kinase. (1123 aa)
	HOXB3	Homeobox B3. (253 aa)
	ENSRBIP00000022924	Uncharacterized protein. (571 aa)
	CDK5RAP3	CDK5 regulatory subunit associated protein 3. (506 aa)
	MFAP5	Microfibril associated protein 5. (158 aa)
	TGFBR3	Transforming growth factor beta receptor 3. (861 aa)
	LOC108526807	Uncharacterized protein. (756 aa)
	ZFPM1	Uncharacterized protein. (143 aa)
	GATA2	GATA binding protein 2. (468 aa)
	SP3	Sp3 transcription factor. (775 aa)
	LYL1	LYL1 basic helix-loop-helix family member. (280 aa)
	LOC108526638	A to I editase domain-containing protein. (193 aa)
	ZFP36L2	ZFP36 ring finger protein like 2. (499 aa)
	CBFB	Core-binding factor subunit beta. (182 aa)
	HIPK1	Homeodomain interacting protein kinase 1. (1417 aa)
	BCR	BCR activator of RhoGEF and GTPase. (1089 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CBFB	GATA2	ENSRBIP00000008602	ENSRBIP00000029914	Core-binding factor subunit beta.	GATA binding protein 2.	0.669
CBFB	HIPK1	ENSRBIP00000008602	ENSRBIP00000008913	Core-binding factor subunit beta.	Homeodomain interacting protein kinase 1.	0.531
CBFB	LYL1	ENSRBIP00000008602	ENSRBIP00000000158	Core-binding factor subunit beta.	LYL1 basic helix-loop-helix family member.	0.687
CBFB	ZFPM1	ENSRBIP00000008602	ENSRBIP00000036412	Core-binding factor subunit beta.	Uncharacterized protein.	0.468
GATA2	CBFB	ENSRBIP00000029914	ENSRBIP00000008602	GATA binding protein 2.	Core-binding factor subunit beta.	0.669
GATA2	LYL1	ENSRBIP00000029914	ENSRBIP00000000158	GATA binding protein 2.	LYL1 basic helix-loop-helix family member.	0.644
GATA2	ZFPM1	ENSRBIP00000029914	ENSRBIP00000036412	GATA binding protein 2.	Uncharacterized protein.	0.855
HIPK1	CBFB	ENSRBIP00000008913	ENSRBIP00000008602	Homeodomain interacting protein kinase 1.	Core-binding factor subunit beta.	0.531
LOC108526638	LOC108526807	ENSRBIP00000001788	ENSRBIP00000033744	A to I editase domain-containing protein.	Uncharacterized protein.	0.917
LOC108526807	LOC108526638	ENSRBIP00000033744	ENSRBIP00000001788	Uncharacterized protein.	A to I editase domain-containing protein.	0.917
LYL1	CBFB	ENSRBIP00000000158	ENSRBIP00000008602	LYL1 basic helix-loop-helix family member.	Core-binding factor subunit beta.	0.687
LYL1	GATA2	ENSRBIP00000000158	ENSRBIP00000029914	LYL1 basic helix-loop-helix family member.	GATA binding protein 2.	0.644
ZFPM1	CBFB	ENSRBIP00000036412	ENSRBIP00000008602	Uncharacterized protein.	Core-binding factor subunit beta.	0.468
ZFPM1	GATA2	ENSRBIP00000036412	ENSRBIP00000029914	Uncharacterized protein.	GATA binding protein 2.	0.855