(12 nodes) Embryonic skeletal joint morphogenesis network (Rhinopithecus bieti)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	HYAL1	Hyaluronidase. (435 aa)
	HOXA11	Homeobox A11. (313 aa)
	COL2A1	Collagen type II alpha 1 chain. (1487 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (231 aa)
	OSR2	Odd-skipped related transciption factor 2. (420 aa)
	ENSRBIP00000022621	Homeobox domain-containing protein. (144 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	OSR1	Odd-skipped related transcription factor 1. (266 aa)
	BMP4	Bone morphogenetic protein 4. (408 aa)
	HOXC11	Homeobox C11. (304 aa)
	SHOX2	Short stature homeobox 2. (355 aa)
	BMP7	Bone morphogenetic protein 7. (431 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	BMP7	ENSRBIP00000039189	ENSRBIP00000042927	Bone morphogenetic protein 4.	Bone morphogenetic protein 7.	0.787
BMP4	CTNNB1	ENSRBIP00000039189	ENSRBIP00000022705	Bone morphogenetic protein 4.	Catenin beta 1.	0.420
BMP4	NOG	ENSRBIP00000039189	ENSRBIP00000003551	Bone morphogenetic protein 4.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.951
BMP7	BMP4	ENSRBIP00000042927	ENSRBIP00000039189	Bone morphogenetic protein 7.	Bone morphogenetic protein 4.	0.787
BMP7	CTNNB1	ENSRBIP00000042927	ENSRBIP00000022705	Bone morphogenetic protein 7.	Catenin beta 1.	0.400
BMP7	NOG	ENSRBIP00000042927	ENSRBIP00000003551	Bone morphogenetic protein 7.	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	0.941
CTNNB1	BMP4	ENSRBIP00000022705	ENSRBIP00000039189	Catenin beta 1.	Bone morphogenetic protein 4.	0.420
CTNNB1	BMP7	ENSRBIP00000022705	ENSRBIP00000042927	Catenin beta 1.	Bone morphogenetic protein 7.	0.400
NOG	BMP4	ENSRBIP00000003551	ENSRBIP00000039189	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Bone morphogenetic protein 4.	0.951
NOG	BMP7	ENSRBIP00000003551	ENSRBIP00000042927	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite.	Bone morphogenetic protein 7.	0.941