(35 nodes) Face morphogenesis network (Rhinopithecus bieti)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ANKRD12	Ankyrin repeat domain 12. (2048 aa)
	ENSRBIP00000016878	Uncharacterized protein. (251 aa)
	ARID5B	AT-rich interaction domain 5B. (1140 aa)
	PLEKHA1	Pleckstrin homology domain containing A1. (389 aa)
	MMP2	Matrix metallopeptidase 2. (660 aa)
	SKI	SKI proto-oncogene. (637 aa)
	SCX	Uncharacterized protein. (179 aa)
	DKK1	Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
	ENSRBIP00000026419	Uncharacterized protein. (249 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa)
	MYH3	Myosin heavy chain 3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1821 aa)
	COL1A1	Collagen type I alpha 1 chain. (1464 aa)
	CRISPLD1	Cysteine rich secretory protein LCCL domain containing 1. (500 aa)
	ASPH	Aspartate beta-hydroxylase. (733 aa)
	STRA6	Stimulated by retinoic acid 6. (706 aa)
	EP300	E1A binding protein p300. (2296 aa)
	CSRNP1	Cysteine and serine rich nuclear protein 1. (593 aa)
	SGPL1	Sphingosine-1-phosphate lyase 1. (568 aa)
	TBX1	T-box transcription factor 1. (371 aa)
	RAB3GAP1	RAB3 GTPase activating protein catalytic subunit 1. (989 aa)
	RRAS	RAS related. (218 aa)
	NIPBL	Nipped-B protein. (2777 aa)
	ANKRD11	Ankyrin repeat domain 11. (2622 aa)
	ENSRBIP00000032719	SH2 domain-containing protein. (203 aa)
	ENSRBIP00000009767	Uncharacterized protein. (546 aa)
	LEF1	Lymphoid enhancer binding factor 1. (398 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	TIPARP	TCDD inducible poly(ADP-ribose) polymerase. (663 aa)
	CRISPLD2	Cysteine rich secretory protein LCCL domain containing 2. (497 aa)
	MSX1	Msh homeobox 1. (303 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (231 aa)
	ENSRBIP00000002079	Uncharacterized protein. (202 aa)
	DLX5	Distal-less homeobox 5. (289 aa)
	CLDN5	Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD11	NIPBL	ENSRBIP00000042994	ENSRBIP00000042218	Ankyrin repeat domain 11.	Nipped-B protein.	0.418
COL1A1	MMP2	ENSRBIP00000031449	ENSRBIP00000020582	Collagen type I alpha 1 chain.	Matrix metallopeptidase 2.	0.537
COL1A1	TGFB1	ENSRBIP00000031449	ENSRBIP00000006822	Collagen type I alpha 1 chain.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.503
COL1A1	TGFB3	ENSRBIP00000031449	ENSRBIP00000026474	Collagen type I alpha 1 chain.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.548
CSRNP1	MSX1	ENSRBIP00000036530	ENSRBIP00000003726	Cysteine and serine rich nuclear protein 1.	Msh homeobox 1.	0.576
DKK1	LEF1	ENSRBIP00000024289	ENSRBIP00000009456	Dickkopf WNT signaling pathway inhibitor 1.	Lymphoid enhancer binding factor 1.	0.557
ENSRBIP00000002079	ENSRBIP00000016878	ENSRBIP00000002079	ENSRBIP00000016878	Uncharacterized protein.	Uncharacterized protein.	0.716
ENSRBIP00000002079	ENSRBIP00000026419	ENSRBIP00000002079	ENSRBIP00000026419	Uncharacterized protein.	Uncharacterized protein.	0.881
ENSRBIP00000016878	ENSRBIP00000002079	ENSRBIP00000016878	ENSRBIP00000002079	Uncharacterized protein.	Uncharacterized protein.	0.716
ENSRBIP00000016878	ENSRBIP00000032719	ENSRBIP00000016878	ENSRBIP00000032719	Uncharacterized protein.	SH2 domain-containing protein.	0.719
ENSRBIP00000026419	ENSRBIP00000002079	ENSRBIP00000026419	ENSRBIP00000002079	Uncharacterized protein.	Uncharacterized protein.	0.881
ENSRBIP00000026419	ENSRBIP00000032719	ENSRBIP00000026419	ENSRBIP00000032719	Uncharacterized protein.	SH2 domain-containing protein.	0.892
ENSRBIP00000032719	ENSRBIP00000016878	ENSRBIP00000032719	ENSRBIP00000016878	SH2 domain-containing protein.	Uncharacterized protein.	0.719
ENSRBIP00000032719	ENSRBIP00000026419	ENSRBIP00000032719	ENSRBIP00000026419	SH2 domain-containing protein.	Uncharacterized protein.	0.892
EP300	LEF1	ENSRBIP00000033605	ENSRBIP00000009456	E1A binding protein p300.	Lymphoid enhancer binding factor 1.	0.975
EP300	TGFB1	ENSRBIP00000033605	ENSRBIP00000006822	E1A binding protein p300.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.541
LEF1	DKK1	ENSRBIP00000009456	ENSRBIP00000024289	Lymphoid enhancer binding factor 1.	Dickkopf WNT signaling pathway inhibitor 1.	0.557
LEF1	EP300	ENSRBIP00000009456	ENSRBIP00000033605	Lymphoid enhancer binding factor 1.	E1A binding protein p300.	0.975
LEF1	MSX1	ENSRBIP00000009456	ENSRBIP00000003726	Lymphoid enhancer binding factor 1.	Msh homeobox 1.	0.579
MMP2	COL1A1	ENSRBIP00000020582	ENSRBIP00000031449	Matrix metallopeptidase 2.	Collagen type I alpha 1 chain.	0.537