(26 nodes) Lung epithelial cell differentiation network (Rhinopithecus bieti)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AGR2	Anterior gradient 2, protein disulphide isomerase family member. (175 aa)
	ENSRBIP00000040717	Uncharacterized protein. (100 aa)
	SAV1	Salvador family WW domain containing protein 1. (384 aa)
	LTA4H	Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family. (610 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	TMEM38B	Transmembrane protein 38B. (291 aa)
	NFIB	Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
	THRA	Thyroid hormone receptor alpha. (524 aa)
	KLF2	Uncharacterized protein. (194 aa)
	THRB	Thyroid hormone receptor beta. (476 aa)
	NKX2-1	NK2 homeobox 1. (401 aa)
	PPP3R1	Uncharacterized protein. (189 aa)
	SPDEF	SAM pointed domain containing ETS transcription factor. (335 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	AIMP2	Aminoacyl tRNA synthetase complex interacting multifunctional protein 2. (320 aa)
	RBBP9	RB binding protein 9, serine hydrolase. (151 aa)
	GRHL2	Grainyhead like transcription factor 2. (625 aa)
	ASCL1	Achaete-scute family bHLH transcription factor 1. (234 aa)
	FNDC3B	Fibronectin type III domain containing 3B. (1178 aa)
	NUMA1	Nuclear mitotic apparatus protein 1. (2118 aa)
	LOC108525471	Uncharacterized protein. (356 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	HOXA5	Homeobox A5. (270 aa)
	YAP1	Yes associated protein 1. (326 aa)
	KRAS	KRAS proto-oncogene, GTPase. (189 aa)
	FOXA1	Forkhead box A1. (436 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGR2	FOXA1	ENSRBIP00000027447	ENSRBIP00000026648	Anterior gradient 2, protein disulphide isomerase family member.	Forkhead box A1.	0.442
AGR2	SPDEF	ENSRBIP00000027447	ENSRBIP00000000498	Anterior gradient 2, protein disulphide isomerase family member.	SAM pointed domain containing ETS transcription factor.	0.632
ASCL1	CREB1	ENSRBIP00000010802	ENSRBIP00000033953	Achaete-scute family bHLH transcription factor 1.	cAMP responsive element binding protein 1.	0.500
CREB1	ASCL1	ENSRBIP00000033953	ENSRBIP00000010802	cAMP responsive element binding protein 1.	Achaete-scute family bHLH transcription factor 1.	0.500
CREB1	CTNNB1	ENSRBIP00000033953	ENSRBIP00000022705	cAMP responsive element binding protein 1.	Catenin beta 1.	0.686
CTNNB1	CREB1	ENSRBIP00000022705	ENSRBIP00000033953	Catenin beta 1.	cAMP responsive element binding protein 1.	0.686
CTNNB1	ENSRBIP00000040717	ENSRBIP00000022705	ENSRBIP00000040717	Catenin beta 1.	Uncharacterized protein.	0.449
CTNNB1	KLF2	ENSRBIP00000022705	ENSRBIP00000028400	Catenin beta 1.	Uncharacterized protein.	0.438
CTNNB1	KRAS	ENSRBIP00000022705	ENSRBIP00000026575	Catenin beta 1.	KRAS proto-oncogene, GTPase.	0.449
CTNNB1	LOC108525471	ENSRBIP00000022705	ENSRBIP00000022332	Catenin beta 1.	Uncharacterized protein.	0.782
CTNNB1	YAP1	ENSRBIP00000022705	ENSRBIP00000025082	Catenin beta 1.	Yes associated protein 1.	0.782
ENSRBIP00000040717	CTNNB1	ENSRBIP00000040717	ENSRBIP00000022705	Uncharacterized protein.	Catenin beta 1.	0.449
FOXA1	AGR2	ENSRBIP00000026648	ENSRBIP00000027447	Forkhead box A1.	Anterior gradient 2, protein disulphide isomerase family member.	0.442
FOXA1	NKX2-1	ENSRBIP00000026648	ENSRBIP00000004346	Forkhead box A1.	NK2 homeobox 1.	0.605
KLF2	CTNNB1	ENSRBIP00000028400	ENSRBIP00000022705	Uncharacterized protein.	Catenin beta 1.	0.438
KRAS	CTNNB1	ENSRBIP00000026575	ENSRBIP00000022705	KRAS proto-oncogene, GTPase.	Catenin beta 1.	0.449
LOC108525471	CTNNB1	ENSRBIP00000022332	ENSRBIP00000022705	Uncharacterized protein.	Catenin beta 1.	0.782
LOC108525471	SAV1	ENSRBIP00000022332	ENSRBIP00000035758	Uncharacterized protein.	Salvador family WW domain containing protein 1.	0.741
NKX2-1	FOXA1	ENSRBIP00000004346	ENSRBIP00000026648	NK2 homeobox 1.	Forkhead box A1.	0.605
NKX2-1	SPDEF	ENSRBIP00000004346	ENSRBIP00000000498	NK2 homeobox 1.	SAM pointed domain containing ETS transcription factor.	0.533