23 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
	CARD9	Caspase recruitment domain family member 9. (536 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (472 aa)
	TLR3	Toll like receptor 3; Belongs to the Toll-like receptor family. (903 aa)
	TLR4	Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
	TLR7	Toll like receptor 7; Belongs to the Toll-like receptor family. (1049 aa)
	WNT5A	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
	GPRC5B	G protein-coupled receptor class C group 5 member B. (654 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (443 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (1153 aa)
	PANX1	Pannexin; Structural component of the gap junctions and the hemichannels. (426 aa)
	PYCARD	PYD and CARD domain containing. (195 aa)
	CD74	CD74 molecule. (294 aa)
	MAPKAPK2	MAPK activated protein kinase 2. (392 aa)
	NOD1	Nucleotide binding oligomerization domain containing 1. (953 aa)
	SPON2	Spondin 2. (331 aa)
	TICAM1	Toll like receptor adaptor molecule 1. (515 aa)
	ENSRBIP00000022247	Uncharacterized protein. (70 aa)
	RTN4	Reticulon. (1172 aa)
	SEMA7A	Semaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (668 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
	ENSRBIP00000011851	Uncharacterized protein. (107 aa)
	SIRT1	Sirtuin 1. (731 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CARD9	MYD88	ENSRBIP00000010007	ENSRBIP00000010319	Caspase recruitment domain family member 9.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.585
CARD9	NOD1	ENSRBIP00000010007	ENSRBIP00000032592	Caspase recruitment domain family member 9.	Nucleotide binding oligomerization domain containing 1.	0.510
CARD9	NOD2	ENSRBIP00000010007	ENSRBIP00000003132	Caspase recruitment domain family member 9.	Nucleotide binding oligomerization domain containing 2.	0.750
CARD9	PYCARD	ENSRBIP00000010007	ENSRBIP00000038602	Caspase recruitment domain family member 9.	PYD and CARD domain containing.	0.400
CARD9	RIPK2	ENSRBIP00000010007	ENSRBIP00000003947	Caspase recruitment domain family member 9.	Receptor interacting serine/threonine kinase 2.	0.936
CARD9	TLR4	ENSRBIP00000010007	ENSRBIP00000006333	Caspase recruitment domain family member 9.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.485
CD36	TLR4	ENSRBIP00000010002	ENSRBIP00000006333	CD36 molecule; Belongs to the CD36 family.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.872
ENSRBIP00000011851	PANX1	ENSRBIP00000011851	ENSRBIP00000039572	Uncharacterized protein.	Pannexin; Structural component of the gap junctions and the hemichannels.	0.852
ENSRBIP00000022247	MYD88	ENSRBIP00000022247	ENSRBIP00000010319	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.491
ENSRBIP00000022247	NOD1	ENSRBIP00000022247	ENSRBIP00000032592	Uncharacterized protein.	Nucleotide binding oligomerization domain containing 1.	0.865
ENSRBIP00000022247	NOD2	ENSRBIP00000022247	ENSRBIP00000003132	Uncharacterized protein.	Nucleotide binding oligomerization domain containing 2.	0.902
ENSRBIP00000022247	TLR4	ENSRBIP00000022247	ENSRBIP00000006333	Uncharacterized protein.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.491
MYD88	CARD9	ENSRBIP00000010319	ENSRBIP00000010007	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Caspase recruitment domain family member 9.	0.585
MYD88	ENSRBIP00000022247	ENSRBIP00000010319	ENSRBIP00000022247	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Uncharacterized protein.	0.491
MYD88	NOD1	ENSRBIP00000010319	ENSRBIP00000032592	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Nucleotide binding oligomerization domain containing 1.	0.458
MYD88	NOD2	ENSRBIP00000010319	ENSRBIP00000003132	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Nucleotide binding oligomerization domain containing 2.	0.553
MYD88	PYCARD	ENSRBIP00000010319	ENSRBIP00000038602	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	PYD and CARD domain containing.	0.527
MYD88	RIPK2	ENSRBIP00000010319	ENSRBIP00000003947	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Receptor interacting serine/threonine kinase 2.	0.491
MYD88	SIRT1	ENSRBIP00000010319	ENSRBIP00000010135	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Sirtuin 1.	0.479
MYD88	TICAM1	ENSRBIP00000010319	ENSRBIP00000024774	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Toll like receptor adaptor molecule 1.	0.604