STRINGSTRING
CBFA2T3 CBFA2T3 CYP27B1 CYP27B1 FGF19 FGF19 ETFBKMT ETFBKMT PRMT3 PRMT3 FMO4 FMO4 SLC22A13 SLC22A13 C1QTNF3 C1QTNF3 SLC27A4 SLC27A4 SLC4A1 SLC4A1 SOGA1 SOGA1 HPCAL1 HPCAL1 C1QTNF12 C1QTNF12 LOC108532992 LOC108532992 HDAC4 HDAC4 GCK GCK CRY1 CRY1 APOE APOE FBP1 FBP1 DGAT2 DGAT2 SERPINA12 SERPINA12 DDIT4 DDIT4 CLK2 CLK2 CDA CDA ERFE ERFE GFI1 GFI1 INSIG1 INSIG1 DKKL1 DKKL1 GIT1 GIT1 ERLIN2 ERLIN2 PLEK PLEK BMP5 BMP5 LEPR LEPR TP53 TP53 PID1 PID1 MALRD1 MALRD1 ENSRBIP00000030776 ENSRBIP00000030776 ATCAY ATCAY TRIB3 TRIB3 EP300 EP300 FAM3A FAM3A NUPR1 NUPR1 PARP1 PARP1 TSPO TSPO BMP2 BMP2 PDZD3 PDZD3 LOC108540985 LOC108540985 BRCA1 BRCA1 LOC108532991 LOC108532991 MST1 MST1 ACACB ACACB NCOR1 NCOR1 SNAI2 SNAI2 ERLIN1 ERLIN1 WDTC1 WDTC1 PROX1 PROX1 FMO2 FMO2 GSK3A GSK3A SNAI1 SNAI1 PPARA PPARA SCAP SCAP TIGAR TIGAR MFSD2A MFSD2A IER3 IER3 STAT3 STAT3 PGP PGP PLIN5 PLIN5 DKK3 DKK3 RD3 RD3 WNT4 WNT4 ACTN3 ACTN3 AKR1C3 AKR1C3 SOX9 SOX9 SIRT4 SIRT4 SIRT1 SIRT1 AKT1 AKT1 CEACAM1 CEACAM1 SIRT6 SIRT6 ADIPOQ ADIPOQ SOD1 SOD1 NFKB1 NFKB1 FIS1 FIS1 APPL2 APPL2 REST REST BCKDK BCKDK FAM3C FAM3C HPCA HPCA CYP7A1 CYP7A1 FMO1 FMO1 PIBF1 PIBF1 ATP2B4 ATP2B4 FLCN FLCN ACMSD ACMSD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CBFA2T3CBFA2/RUNX1 partner transcriptional co-repressor 3. (636 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (508 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
ETFBKMTElectron transfer flavoprotein subunit beta lysine methyltransferase. (262 aa)
PRMT3Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (519 aa)
FMO4Dimethylaniline monooxygenase [N-oxide-forming]. (558 aa)
SLC22A13Solute carrier family 22 member 13. (551 aa)
C1QTNF3C1q domain-containing protein. (263 aa)
SLC27A4Solute carrier family 27 member 4. (572 aa)
SLC4A1Anion exchange protein. (959 aa)
SOGA1Suppressor of glucose, autophagy associated 1. (1456 aa)
HPCAL1Hippocalcin like 1. (193 aa)
C1QTNF12C1q and TNF related 12. (278 aa)
LOC108532992Aldo-keto reductase family 1 member C1. (303 aa)
HDAC4Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1112 aa)
GCKPhosphotransferase. (466 aa)
CRY1Cryptochrome circadian regulator 1. (586 aa)
APOEApolipoprotein E. (317 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (293 aa)
DGAT2Diacylglycerol O-acyltransferase 2. (388 aa)
SERPINA12Serpin family A member 12; Belongs to the serpin family. (414 aa)
DDIT4DNA damage inducible transcript 4. (233 aa)
CLK2CDC like kinase 2; Belongs to the protein kinase superfamily. (499 aa)
CDACytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (146 aa)
ERFEErythroferrone. (348 aa)
GFI1Growth factor independent 1 transcriptional repressor. (422 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (283 aa)
DKKL1Dickkopf like acrosomal protein 1. (242 aa)
GIT1GIT ArfGAP 1. (817 aa)
ERLIN2ER lipid raft associated 2. (380 aa)
PLEKPleckstrin. (350 aa)
BMP5TGF_BETA_2 domain-containing protein. (154 aa)
LEPRLeptin receptor. (1169 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
PID1Phosphotyrosine interaction domain containing 1. (250 aa)
MALRD1MAM and LDL receptor class A domain containing 1. (2163 aa)
ENSRBIP00000030776Protein kinase domain-containing protein. (232 aa)
ATCAYATCAY kinesin light chain interacting caytaxin. (343 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
EP300E1A binding protein p300. (2296 aa)
FAM3AFamily with sequence similarity 3 member A. (244 aa)
NUPR1Nuclear protein 1, transcriptional regulator. (100 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa)
TSPOTranslocator protein. (169 aa)
BMP2Bone morphogenetic protein 2. (321 aa)
PDZD3PDZ domain containing 3. (505 aa)
LOC108540985UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family. (534 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1818 aa)
LOC108532991Aldo_ket_red domain-containing protein. (323 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (725 aa)
ACACBAcetyl-CoA carboxylase beta. (2458 aa)
NCOR1Nuclear receptor corepressor 1. (2441 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
ERLIN1ER lipid raft associated 1. (348 aa)
WDTC1WD and tetratricopeptide repeats 1. (666 aa)
PROX1Prospero homeobox 1. (737 aa)
FMO2Dimethylaniline monooxygenase [N-oxide-forming]. (535 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (444 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
PPARAPeroxisome proliferator activated receptor alpha. (468 aa)
SCAPSREBF chaperone. (1469 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (316 aa)
MFSD2AMajor facilitator superfamily domain containing 2A. (530 aa)
IER3Immediate early response 3. (156 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
PGPUncharacterized protein. (120 aa)
PLIN5Perilipin; Belongs to the perilipin family. (462 aa)
DKK3Dickkopf WNT signaling pathway inhibitor 3. (350 aa)
RD3Retinal degeneration 3, GUCY2D regulator. (195 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (331 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (937 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (343 aa)
SOX9SRY-box transcription factor 9. (305 aa)
SIRT4NAD-dependent protein lipoamidase sirtuin-4, mitochondrial; Acts as NAD-dependent protein lipoamidase, ADP-ribosyl transferase and deacetylase. Catalyzes more efficiently removal of lipoyl- and biotinyl- than acetyl-lysine modifications. Inhibits the pyruvate dehydrogenase complex (PDH) activity via the enzymatic hydrolysis of the lipoamide cofactor from the E2 component, DLAT, in a phosphorylation-independent manner. Catalyzes the transfer of ADP- ribosyl groups onto target proteins, including mitochondrial GLUD1, inhibiting GLUD1 enzyme activity. Acts as a negative regulator of mitoc [...] (314 aa)
SIRT1Sirtuin 1. (731 aa)
AKT1AKT serine/threonine kinase 1. (486 aa)
CEACAM1Uncharacterized protein. (525 aa)
SIRT6Sirtuin 6. (355 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (275 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (664 aa)
RESTRE1 silencing transcription factor. (1080 aa)
BCKDKProtein-serine/threonine kinase. (412 aa)
FAM3CFamily with sequence similarity 3 member C. (230 aa)
HPCAHippocalcin. (193 aa)
CYP7A1Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. (405 aa)
FMO1Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (691 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1205 aa)
FLCNFolliculin. (579 aa)
ACMSD2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; Converts alpha-amino-beta-carboxymuconate-epsilon- semialdehyde (ACMS) to alpha-aminomuconate semialdehyde (AMS). Belongs to the metallo-dependent hydrolases superfamily. (336 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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