STRINGSTRING
DFFA DFFA BCL2L11 BCL2L11 KIFAP3 KIFAP3 CHEK2 CHEK2 ADA ADA BCL11B BCL11B GLI3 GLI3 TP53 TP53 BAX BAX BAK1 BAK1 WNT5A WNT5A ENSRBIP00000042716 ENSRBIP00000042716
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DFFADNA fragmentation factor subunit alpha. (331 aa)
BCL2L11Bcl-2-like protein 11; Induces apoptosis and anoikis. Belongs to the Bcl-2 family. (198 aa)
KIFAP3Kinesin associated protein 3. (789 aa)
CHEK2Checkpoint kinase 2. (589 aa)
ADAA_deaminase domain-containing protein. (443 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (864 aa)
GLI3GLI family zinc finger 3. (1555 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
BAXBCL2 associated X, apoptosis regulator. (197 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
ENSRBIP00000042716A_deaminase domain-containing protein. (344 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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