50 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SOX9	SRY-box transcription factor 9. (305 aa)
	HTR2B	5-hydroxytryptamine receptor 2B. (481 aa)
	MT3	Metallothionein 3; Belongs to the metallothionein superfamily. Type 1 family. (113 aa)
	HESX1	HESX homeobox 1. (185 aa)
	FGF18	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
	AVP	Arginine vasopressin; Belongs to the vasopressin/oxytocin family. (164 aa)
	GRB10	Growth factor receptor bound protein 10. (593 aa)
	DUSP6	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
	BTN2A2	Uncharacterized protein. (518 aa)
	CTSH	Cathepsin H; Belongs to the peptidase C1 family. (335 aa)
	ZFP36L1	Uncharacterized protein. (327 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
	NOD1	Nucleotide binding oligomerization domain containing 1. (953 aa)
	ANKRD26	Ankyrin repeat domain 26. (1667 aa)
	FGF23	Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (251 aa)
	EDN1	Endothelin 1. (211 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
	TNFSF11	Tumor necrosis factor ligand superfamily member. (317 aa)
	TF	Transferrin; Belongs to the transferrin family. (700 aa)
	IQGAP3	IQ motif containing GTPase activating protein 3. (1663 aa)
	NLRP12	NLR family pyrin domain containing 12. (1055 aa)
	ENSRBIP00000022247	Uncharacterized protein. (70 aa)
	BRAF	B-Raf proto-oncogene, serine/threonine kinase. (753 aa)
	LOC108527746	Uncharacterized protein. (511 aa)
	SMAD4	Mothers against decapentaplegic homolog. (552 aa)
	WNK4	WNK lysine deficient protein kinase 4. (1243 aa)
	ITGAV	Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
	TBC1D10C	TBC1 domain family member 10C. (446 aa)
	LOC108521987	DUF3496 domain-containing protein. (153 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
	FLCN	Folliculin. (579 aa)
	DUSP9	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (383 aa)
	DUSP5	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (363 aa)
	KARS1	Lysine--tRNA ligase. (650 aa)
	ENSRBIP00000011760	Uncharacterized protein. (118 aa)
	ENSRBIP00000011319	Protein kinase domain-containing protein. (265 aa)
	ENSRBIP00000009022	CCDC144C domain-containing protein. (348 aa)
	IGF1	Insulin like growth factor 1. (208 aa)
	ABL1	Tyrosine-protein kinase. (1149 aa)
	ENSRBIP00000007851	ANK_REP_REGION domain-containing protein. (97 aa)
	TLR4	Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
	ZFP36L2	ZFP36 ring finger protein like 2. (499 aa)
	C1QL4	Complement C1q like 4. (238 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (443 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (1153 aa)
	DUSP7	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
	KDR	Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
	FGF10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
	SPRY1	Sprouty RTK signaling antagonist 1. (319 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	GRB10	ENSRBIP00000007933	ENSRBIP00000035611	Tyrosine-protein kinase.	Growth factor receptor bound protein 10.	0.412
ABL1	MAPK1	ENSRBIP00000007933	ENSRBIP00000026426	Tyrosine-protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.559
ABL1	MAPK3	ENSRBIP00000007933	ENSRBIP00000000532	Tyrosine-protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.468
ABL1	MYC	ENSRBIP00000007933	ENSRBIP00000033415	Tyrosine-protein kinase.	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes.	0.435
BRAF	IQGAP3	ENSRBIP00000021720	ENSRBIP00000024239	B-Raf proto-oncogene, serine/threonine kinase.	IQ motif containing GTPase activating protein 3.	0.471
BRAF	MAPK1	ENSRBIP00000021720	ENSRBIP00000026426	B-Raf proto-oncogene, serine/threonine kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.577
BRAF	MAPK3	ENSRBIP00000021720	ENSRBIP00000000532	B-Raf proto-oncogene, serine/threonine kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.606
BRAF	SMAD4	ENSRBIP00000021720	ENSRBIP00000018874	B-Raf proto-oncogene, serine/threonine kinase.	Mothers against decapentaplegic homolog.	0.415
CTSH	TLR4	ENSRBIP00000034802	ENSRBIP00000006333	Cathepsin H; Belongs to the peptidase C1 family.	Toll like receptor 4; Belongs to the Toll-like receptor family.	0.443
DUSP5	MAPK1	ENSRBIP00000015133	ENSRBIP00000026426	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.520
DUSP5	MAPK3	ENSRBIP00000015133	ENSRBIP00000000532	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.601
DUSP6	DUSP9	ENSRBIP00000035432	ENSRBIP00000015261	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.527
DUSP6	MAPK1	ENSRBIP00000035432	ENSRBIP00000026426	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.989
DUSP6	MAPK3	ENSRBIP00000035432	ENSRBIP00000000532	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.984
DUSP7	DUSP9	ENSRBIP00000002710	ENSRBIP00000015261	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.691
DUSP7	MAPK1	ENSRBIP00000002710	ENSRBIP00000026426	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.970
DUSP7	MAPK3	ENSRBIP00000002710	ENSRBIP00000000532	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.970
DUSP9	DUSP6	ENSRBIP00000015261	ENSRBIP00000035432	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.527
DUSP9	DUSP7	ENSRBIP00000015261	ENSRBIP00000002710	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	0.691
DUSP9	MAPK1	ENSRBIP00000015261	ENSRBIP00000026426	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.967