21 items (Rhinopithecus bieti) - STRING interaction network

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	MAPK3	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
	TNIP2	CCHC NOA-type domain-containing protein. (337 aa)
	EGR1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (541 aa)
	ST18	ST18 C2H2C-type zinc finger transcription factor. (1038 aa)
	IRAK3	Interleukin 1 receptor associated kinase 3. (596 aa)
	ENSRBIP00000006958	TNF receptor-associated factor. (473 aa)
	PLCB1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
	IL1RL2	Interleukin 1 receptor like 2. (652 aa)
	IL1R1	Interleukin 1 receptor type 1. (568 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa)
	RELA	Uncharacterized protein. (282 aa)
	TOLLIP	Toll interacting protein. (274 aa)
	IRAK1	Interleukin 1 receptor associated kinase 1. (702 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
	IRAK2	Interleukin 1 receptor associated kinase 2. (537 aa)
	RPS6KA4	Ribosomal protein S6 kinase. (771 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
	RPS6KA5	Non-specific serine/threonine protein kinase. (684 aa)
	ENSRBIP00000038500	RHD domain-containing protein. (112 aa)
	IRAK4	Interleukin 1 receptor associated kinase 4. (461 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EGR1	MAPK3	ENSRBIP00000003784	ENSRBIP00000000532	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.931
ENSRBIP00000006958	ENSRBIP00000038500	ENSRBIP00000006958	ENSRBIP00000038500	TNF receptor-associated factor.	RHD domain-containing protein.	0.407
ENSRBIP00000006958	IKBKB	ENSRBIP00000006958	ENSRBIP00000027811	TNF receptor-associated factor.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.819
ENSRBIP00000006958	IL1B	ENSRBIP00000006958	ENSRBIP00000017788	TNF receptor-associated factor.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.668
ENSRBIP00000006958	IL1R1	ENSRBIP00000006958	ENSRBIP00000009596	TNF receptor-associated factor.	Interleukin 1 receptor type 1.	0.837
ENSRBIP00000006958	IL1RL2	ENSRBIP00000006958	ENSRBIP00000007483	TNF receptor-associated factor.	Interleukin 1 receptor like 2.	0.653
ENSRBIP00000006958	IRAK1	ENSRBIP00000006958	ENSRBIP00000026395	TNF receptor-associated factor.	Interleukin 1 receptor associated kinase 1.	0.971
ENSRBIP00000006958	IRAK2	ENSRBIP00000006958	ENSRBIP00000029478	TNF receptor-associated factor.	Interleukin 1 receptor associated kinase 2.	0.945
ENSRBIP00000006958	IRAK3	ENSRBIP00000006958	ENSRBIP00000006603	TNF receptor-associated factor.	Interleukin 1 receptor associated kinase 3.	0.699
ENSRBIP00000006958	IRAK4	ENSRBIP00000006958	ENSRBIP00000038830	TNF receptor-associated factor.	Interleukin 1 receptor associated kinase 4.	0.831
ENSRBIP00000006958	MYD88	ENSRBIP00000006958	ENSRBIP00000010319	TNF receptor-associated factor.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.914
ENSRBIP00000006958	RELA	ENSRBIP00000006958	ENSRBIP00000018109	TNF receptor-associated factor.	Uncharacterized protein.	0.407
ENSRBIP00000006958	TOLLIP	ENSRBIP00000006958	ENSRBIP00000021402	TNF receptor-associated factor.	Toll interacting protein.	0.699
ENSRBIP00000038500	ENSRBIP00000006958	ENSRBIP00000038500	ENSRBIP00000006958	RHD domain-containing protein.	TNF receptor-associated factor.	0.407
ENSRBIP00000038500	IKBKB	ENSRBIP00000038500	ENSRBIP00000027811	RHD domain-containing protein.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.835
ENSRBIP00000038500	IL1B	ENSRBIP00000038500	ENSRBIP00000017788	RHD domain-containing protein.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.535
ENSRBIP00000038500	IRAK1	ENSRBIP00000038500	ENSRBIP00000026395	RHD domain-containing protein.	Interleukin 1 receptor associated kinase 1.	0.478
ENSRBIP00000038500	MYD88	ENSRBIP00000038500	ENSRBIP00000010319	RHD domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.568
ENSRBIP00000038500	RELA	ENSRBIP00000038500	ENSRBIP00000018109	RHD domain-containing protein.	Uncharacterized protein.	0.869
ENSRBIP00000038500	RPS6KA4	ENSRBIP00000038500	ENSRBIP00000032850	RHD domain-containing protein.	Ribosomal protein S6 kinase.	0.461