(16 nodes) Nephron tubule formation network (Rhinopithecus bieti)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SIX1	SIX homeobox 1. (284 aa)
	IRX1	Iroquois homeobox 1. (466 aa)
	WNT6	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa)
	NOG	Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (231 aa)
	IRX3	Iroquois homeobox 3. (502 aa)
	PAX2	Paired box 2. (242 aa)
	SOX9	SRY-box transcription factor 9. (305 aa)
	GDNF	Glial cell derived neurotrophic factor. (228 aa)
	GATA3	GATA binding protein 3. (444 aa)
	IRX2	Iroquois homeobox 2. (446 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	HES5	Hes family bHLH transcription factor 5. (152 aa)
	WNT9B	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
	OSR1	Odd-skipped related transcription factor 1. (266 aa)
	SOX8	SRY-box transcription factor 8. (429 aa)
	HS2ST1	Heparan sulfate 2-O-sulfotransferase 1. (356 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTNNB1	SOX8	ENSRBIP00000022705	ENSRBIP00000032516	Catenin beta 1.	SRY-box transcription factor 8.	0.569
CTNNB1	SOX9	ENSRBIP00000022705	ENSRBIP00000009330	Catenin beta 1.	SRY-box transcription factor 9.	0.778
CTNNB1	WNT6	ENSRBIP00000022705	ENSRBIP00000001373	Catenin beta 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.523
CTNNB1	WNT9B	ENSRBIP00000022705	ENSRBIP00000027103	Catenin beta 1.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.438
IRX1	IRX2	ENSRBIP00000000733	ENSRBIP00000014252	Iroquois homeobox 1.	Iroquois homeobox 2.	0.466
IRX2	IRX1	ENSRBIP00000014252	ENSRBIP00000000733	Iroquois homeobox 2.	Iroquois homeobox 1.	0.466
IRX2	IRX3	ENSRBIP00000014252	ENSRBIP00000005251	Iroquois homeobox 2.	Iroquois homeobox 3.	0.582
IRX3	IRX2	ENSRBIP00000005251	ENSRBIP00000014252	Iroquois homeobox 3.	Iroquois homeobox 2.	0.582
PAX2	SIX1	ENSRBIP00000006372	ENSRBIP00000040487	Paired box 2.	SIX homeobox 1.	0.463
SIX1	PAX2	ENSRBIP00000040487	ENSRBIP00000006372	SIX homeobox 1.	Paired box 2.	0.463
SOX8	CTNNB1	ENSRBIP00000032516	ENSRBIP00000022705	SRY-box transcription factor 8.	Catenin beta 1.	0.569
SOX9	CTNNB1	ENSRBIP00000009330	ENSRBIP00000022705	SRY-box transcription factor 9.	Catenin beta 1.	0.778
WNT6	CTNNB1	ENSRBIP00000001373	ENSRBIP00000022705	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Catenin beta 1.	0.523
WNT6	WNT9B	ENSRBIP00000001373	ENSRBIP00000027103	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.582
WNT9B	CTNNB1	ENSRBIP00000027103	ENSRBIP00000022705	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Catenin beta 1.	0.438
WNT9B	WNT6	ENSRBIP00000027103	ENSRBIP00000001373	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.582