STRINGSTRING
YJEFN3 YJEFN3 BRCA2 BRCA2 CEP120 CEP120 RUNX1 RUNX1 FGF10 FGF10 FGF4 FGF4 WNT3 WNT3 SFRP2 SFRP2 NES NES KDR KDR SFN SFN SHB SHB IFT20 IFT20 TGFB1 TGFB1 WNT2B WNT2B RUNX2 RUNX2 TIAL1 TIAL1 KDF1 KDF1 OVOL1 OVOL1 ETV6 ETV6 RARG RARG TP63 TP63 HOXA3 HOXA3 CEBPA CEBPA SHH SHH ID4 ID4 IRF6 IRF6 RARB RARB BYSL BYSL PTCH1 PTCH1 TRIM71 TRIM71 ELL3 ELL3 ERCC2 ERCC2 WNT10B WNT10B OSR2 OSR2 IRS2 IRS2 NR2E1 NR2E1 XRCC5 XRCC5 TBX3 TBX3 SCRG1 SCRG1 SART3 SART3 LOC108525471 LOC108525471 CTNNB1 CTNNB1 ENSRBIP00000023025 ENSRBIP00000023025 RNF43 RNF43 MECOM MECOM YAP1 YAP1 CDKN2C CDKN2C GLI3 GLI3 FGF8 FGF8 TP53 TP53 AXIN2 AXIN2 FGF9 FGF9 NFIB NFIB LIG4 LIG4 WNT1 WNT1 WNT7B WNT7B SNAI2 SNAI2 SIX2 SIX2 PBX1 PBX1 PRRX1 PRRX1 HMX2 HMX2 CTC1 CTC1 ARIH2 ARIH2 WNT11 WNT11 CD109 CD109 BABAM1 BABAM1 YTHDF2 YTHDF2 WNT5A WNT5A SHOX2 SHOX2 NF1 NF1 CD34 CD34
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
YJEFN3YjeF N-terminal domain containing 3. (293 aa)
BRCA2Uncharacterized protein. (386 aa)
CEP120Centrosomal protein 120. (1022 aa)
RUNX1RUNX family transcription factor 1. (264 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (206 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
NESNestin; Belongs to the intermediate filament family. (1719 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
SFNStratifin; Belongs to the 14-3-3 family. (248 aa)
SHBSH2 domain containing adaptor protein B. (509 aa)
IFT20Intraflagellar transport 20. (158 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (391 aa)
RUNX2RUNX family transcription factor 2. (610 aa)
TIAL1TIA1 cytotoxic granule associated RNA binding protein like 1. (392 aa)
KDF1Keratinocyte differentiation factor 1. (398 aa)
OVOL1Ovo like transcriptional repressor 1. (260 aa)
ETV6ETS variant 6. (452 aa)
RARGUncharacterized protein. (456 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
HOXA3Homeobox A3. (434 aa)
CEBPABZIP domain-containing protein. (141 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (427 aa)
ID4Inhibitor of DNA binding 4, HLH protein. (165 aa)
IRF6Interferon regulatory factor 6. (467 aa)
RARBRetinoic acid receptor beta. (448 aa)
BYSLBystin like. (437 aa)
PTCH1Patched 1. (1455 aa)
TRIM71Tripartite motif containing 71. (749 aa)
ELL3Elongation factor for RNA polymerase II 3. (397 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (675 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
OSR2Odd-skipped related transciption factor 2. (420 aa)
IRS2Insulin receptor substrate 2. (904 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (421 aa)
XRCC5X-ray repair cross complementing 5. (805 aa)
TBX3T-box transcription factor 3. (743 aa)
SCRG1Stimulator of chondrogenesis 1. (98 aa)
SART3Spliceosome associated factor 3, U4/U6 recycling protein. (963 aa)
LOC108525471Uncharacterized protein. (356 aa)
CTNNB1Catenin beta 1. (781 aa)
ENSRBIP00000023025Uncharacterized protein. (387 aa)
RNF43RING-type domain-containing protein. (782 aa)
MECOMMDS1 and EVI1 complex locus. (1217 aa)
YAP1Yes associated protein 1. (326 aa)
CDKN2CCyclin dependent kinase inhibitor 2C. (168 aa)
GLI3GLI family zinc finger 3. (1555 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
AXIN2Axin 2. (843 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (570 aa)
LIG4DNA ligase. (901 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
SIX2SIX homeobox 2. (292 aa)
PBX1PBX homeobox 1. (465 aa)
PRRX1Paired related homeobox 1. (245 aa)
HMX2H6 family homeobox 2. (273 aa)
CTC1CST telomere replication complex component 1. (1217 aa)
ARIH2RBR-type E3 ubiquitin transferase. (493 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (374 aa)
CD109CD109 molecule. (1404 aa)
BABAM1BRISC and BRCA1 A complex member 1. (329 aa)
YTHDF2YTH N6-methyladenosine RNA binding protein 2. (579 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (380 aa)
SHOX2Short stature homeobox 2. (355 aa)
NF1Neurofibromin 1. (2822 aa)
CD34CD34 molecule. (385 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
Server load: low (16%) [HD]