13 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	LOC108515415	CARD domain-containing protein. (201 aa)
	NLRC4	NLR family CARD domain containing 4. (1024 aa)
	BFAR	Bifunctional apoptosis regulator. (450 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (443 aa)
	NOL3	CARD domain-containing protein. (271 aa)
	ENSRBIP00000022247	Uncharacterized protein. (70 aa)
	RIOK3	Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. (603 aa)
	FADD	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
	CARD16	Caspase recruitment domain family member 16. (197 aa)
	ENSRBIP00000042117	CARD domain-containing protein. (53 aa)
	CTSG	Cathepsin G; Belongs to the peptidase S1 family. (255 aa)
	CARD18	CARD domain-containing protein. (91 aa)
	BCL2L10	Uncharacterized protein. (204 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CARD16	CARD18	ENSRBIP00000034697	ENSRBIP00000028700	Caspase recruitment domain family member 16.	CARD domain-containing protein.	0.918
CARD16	ENSRBIP00000042117	ENSRBIP00000034697	ENSRBIP00000042117	Caspase recruitment domain family member 16.	CARD domain-containing protein.	0.917
CARD16	NLRC4	ENSRBIP00000034697	ENSRBIP00000001613	Caspase recruitment domain family member 16.	NLR family CARD domain containing 4.	0.540
CARD18	CARD16	ENSRBIP00000028700	ENSRBIP00000034697	CARD domain-containing protein.	Caspase recruitment domain family member 16.	0.918
CARD18	ENSRBIP00000042117	ENSRBIP00000028700	ENSRBIP00000042117	CARD domain-containing protein.	CARD domain-containing protein.	0.900
CARD18	NLRC4	ENSRBIP00000028700	ENSRBIP00000001613	CARD domain-containing protein.	NLR family CARD domain containing 4.	0.445
ENSRBIP00000022247	FADD	ENSRBIP00000022247	ENSRBIP00000026089	Uncharacterized protein.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.620
ENSRBIP00000042117	CARD16	ENSRBIP00000042117	ENSRBIP00000034697	CARD domain-containing protein.	Caspase recruitment domain family member 16.	0.917
ENSRBIP00000042117	CARD18	ENSRBIP00000042117	ENSRBIP00000028700	CARD domain-containing protein.	CARD domain-containing protein.	0.900
ENSRBIP00000042117	NLRC4	ENSRBIP00000042117	ENSRBIP00000001613	CARD domain-containing protein.	NLR family CARD domain containing 4.	0.445
FADD	ENSRBIP00000022247	ENSRBIP00000026089	ENSRBIP00000022247	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Uncharacterized protein.	0.620
FADD	RIPK2	ENSRBIP00000026089	ENSRBIP00000003947	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	Receptor interacting serine/threonine kinase 2.	0.620
NLRC4	CARD16	ENSRBIP00000001613	ENSRBIP00000034697	NLR family CARD domain containing 4.	Caspase recruitment domain family member 16.	0.540
NLRC4	CARD18	ENSRBIP00000001613	ENSRBIP00000028700	NLR family CARD domain containing 4.	CARD domain-containing protein.	0.445
NLRC4	ENSRBIP00000042117	ENSRBIP00000001613	ENSRBIP00000042117	NLR family CARD domain containing 4.	CARD domain-containing protein.	0.445
RIPK2	FADD	ENSRBIP00000003947	ENSRBIP00000026089	Receptor interacting serine/threonine kinase 2.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.620