STRINGSTRING
ENSRBIP00000001402 ENSRBIP00000001402 SMURF2 SMURF2 TNKS2 TNKS2 LOC108520621 LOC108520621 ENSRBIP00000000027 ENSRBIP00000000027 ENSRBIP00000012047 ENSRBIP00000012047 UBR5 UBR5 AMER1 AMER1 SCEL SCEL TRPM4 TRPM4 RSPO1 RSPO1 PPM1B PPM1B YAP1 YAP1 RSPO2 RSPO2 PPM1A PPM1A LOC108525471 LOC108525471 NLE1 NLE1 FAM53B FAM53B ADGRA2 ADGRA2 BAMBI BAMBI RNF220 RNF220 LYPD6 LYPD6 SEMA5A SEMA5A WLS WLS PPM1N PPM1N RUVBL1 RUVBL1 ATP6AP2 ATP6AP2 CAPRIN2 CAPRIN2 JUP JUP ZEB2 ZEB2 ARNTL ARNTL SFRP1 SFRP1 VPS35 VPS35 EGF EGF ENSRBIP00000016243 ENSRBIP00000016243 CAV1 CAV1 TTC21B TTC21B LOC108539701 LOC108539701 WNT10B WNT10B FGFR2 FGFR2 ENSRBIP00000014561 ENSRBIP00000014561 ENSRBIP00000014084 ENSRBIP00000014084 WNK1 WNK1 PLEKHA4 PLEKHA4 GPC3 GPC3 LRRK2 LRRK2 KANK1 KANK1 JRK JRK NFKB1 NFKB1 FGF9 FGF9 RPS12 RPS12 LGR6 LGR6 PTK7 PTK7 DACT1 DACT1 USP47 USP47 RECK RECK CCAR2 CCAR2 ENSRBIP00000009378 ENSRBIP00000009378 WNK2 WNK2 TBL1X TBL1X ASPM ASPM TGFB1 TGFB1 PIN1 PIN1 SMAD3 SMAD3 USP34 USP34 DAAM2 DAAM2 TBL1XR1 TBL1XR1 CDH3 CDH3 FZD9 FZD9 PRDM15 PRDM15 LOC108525718 LOC108525718 VCP VCP DKK2 DKK2 SFRP2 SFRP2 SRC SRC RNF146 RNF146 SFRP4 SFRP4 DLX5 DLX5 SOX4 SOX4 TMEM9 TMEM9 FGF10 FGF10 TNKS TNKS COL1A1 COL1A1 ENSRBIP00000031768 ENSRBIP00000031768 WNT3A WNT3A HHEX HHEX EDA EDA GPC5 GPC5 LOC108521460 LOC108521460 LRRK1 LRRK1 DAPK3 DAPK3 EGFR EGFR DDX3X DDX3X CTDNEP1 CTDNEP1 ENSRBIP00000037879 ENSRBIP00000037879 TMEM198 TMEM198 LGR4 LGR4 FRAT1 FRAT1 GPRC5B GPRC5B LGR5 LGR5 GID8 GID8 USP8 USP8 RSPO3 RSPO3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSRBIP0000000140240S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (138 aa)
SMURF2SMAD specific E3 ubiquitin protein ligase 2. (719 aa)
TNKS2Poly [ADP-ribose] polymerase. (1165 aa)
LOC10852062140S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (132 aa)
ENSRBIP00000000027Uncharacterized protein. (53 aa)
ENSRBIP00000012047Peptidyl-prolyl cis-trans isomerase. (154 aa)
UBR5Ubiquitin protein ligase E3 component n-recognin 5. (2727 aa)
AMER1APC membrane recruitment protein 1. (805 aa)
SCELSciellin. (698 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1052 aa)
RSPO1R-spondin 1. (262 aa)
PPM1BProtein phosphatase, Mg2+/Mn2+ dependent 1B. (479 aa)
YAP1Yes associated protein 1. (326 aa)
RSPO2R-spondin 2. (243 aa)
PPM1AProtein phosphatase, Mg2+/Mn2+ dependent 1A. (455 aa)
LOC108525471Uncharacterized protein. (356 aa)
NLE1Notchless homolog 1. (514 aa)
FAM53BFamily with sequence similarity 53 member B. (425 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1324 aa)
BAMBIBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa)
RNF220RNF220 domain-containing protein. (234 aa)
LYPD6LY6/PLAUR domain containing 6. (171 aa)
SEMA5ASemaphorin 5A. (1035 aa)
WLSWnt ligand secretion mediator. (543 aa)
PPM1NProtein phosphatase, Mg2+/Mn2+ dependent 1N (putative). (388 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (290 aa)
CAPRIN2Caprin family member 2. (1096 aa)
JUPJunction plakoglobin. (709 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1224 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (594 aa)
SFRP1Secreted frizzled related protein 1. (313 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (778 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
ENSRBIP0000001624340S ribosomal protein S12; Belongs to the eukaryotic ribosomal protein eS12 family. (145 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
TTC21BTetratricopeptide repeat domain 21B. (1316 aa)
LOC108539701Uncharacterized protein. (833 aa)
WNT10BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
ENSRBIP00000014561C2H2-type domain-containing protein. (258 aa)
ENSRBIP00000014084Uncharacterized protein. (147 aa)
WNK1WNK lysine deficient protein kinase 1. (2806 aa)
PLEKHA4Pleckstrin homology domain containing A4. (732 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (357 aa)
LRRK2Protein kinase domain-containing protein. (537 aa)
KANK1KN motif and ankyrin repeat domains 1. (1351 aa)
JRKJrk helix-turn-helix protein. (556 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
FGF9Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
RPS12Ribosomal protein S12. (132 aa)
LGR6Leucine rich repeat containing G protein-coupled receptor 6. (967 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1078 aa)
DACT1Dishevelled binding antagonist of beta catenin 1. (837 aa)
USP47Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1375 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (963 aa)
CCAR2Cell cycle and apoptosis regulator 2. (923 aa)
ENSRBIP00000009378Uncharacterized protein. (115 aa)
WNK2WNK lysine deficient protein kinase 2. (2163 aa)
TBL1XTransducin beta like 1 X-linked. (586 aa)
ASPMAbnormal spindle microtubule assembly. (3411 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
SMAD3Mothers against decapentaplegic homolog. (480 aa)
USP34Ubiquitin specific peptidase 34; Belongs to the peptidase C19 family. (3323 aa)
DAAM2Dishevelled associated activator of morphogenesis 2. (1035 aa)
TBL1XR1Transducin beta like 1 X-linked receptor 1. (514 aa)
CDH3Cadherin 3; Cadherins are calcium-dependent cell adhesion proteins. (829 aa)
FZD9Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (591 aa)
PRDM15PR/SET domain 15. (1597 aa)
LOC10852571840S ribosomal protein S12. (132 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
DKK2Dickkopf WNT signaling pathway inhibitor 2. (259 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
SRCTyrosine-protein kinase. (627 aa)
RNF146Ring finger protein 146. (360 aa)
SFRP4Secreted frizzled related protein 4. (368 aa)
DLX5Distal-less homeobox 5. (289 aa)
SOX4Transcription factor SOX. (475 aa)
TMEM9Transmembrane protein 9. (183 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
TNKSPoly [ADP-ribose] polymerase. (1276 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
ENSRBIP00000031768Uncharacterized protein. (245 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
HHEXHematopoietically expressed homeobox. (270 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (234 aa)
GPC5Glypican 5; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (353 aa)
LOC108521460Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa)
LRRK1Leucine rich repeat kinase 1. (2026 aa)
DAPK3Death associated protein kinase 3. (365 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
DDX3XDEAD-box helicase 3 X-linked; Belongs to the DEAD box helicase family. (625 aa)
CTDNEP1CTD nuclear envelope phosphatase 1. (244 aa)
ENSRBIP00000037879PPM-type phosphatase domain-containing protein. (342 aa)
TMEM198Transmembrane protein 198. (360 aa)
LGR4Leucine rich repeat containing G protein-coupled receptor 4. (931 aa)
FRAT1FRAT regulator of WNT signaling pathway 1. (257 aa)
GPRC5BG protein-coupled receptor class C group 5 member B. (654 aa)
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (907 aa)
GID8GID complex subunit 8 homolog. (228 aa)
USP8Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1105 aa)
RSPO3R-spondin 3. (293 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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