20 items (Rhinopithecus bieti) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	CIDEB	Cell death inducing DFFA like effector b. (219 aa)
	NLRC4	NLR family CARD domain containing 4. (1024 aa)
	BAK1	BCL2 antagonist/killer 1. (211 aa)
	ASPH	Aspartate beta-hydroxylase. (733 aa)
	LGMN	Legumain. (433 aa)
	CASP8	Caspase 8; Belongs to the peptidase C14A family. (542 aa)
	BAD	BCL2 associated agonist of cell death. (167 aa)
	PYCARD	PYD and CARD domain containing. (195 aa)
	CASP6	Caspase 6; Belongs to the peptidase C14A family. (288 aa)
	ENSRBIP00000009112	Uncharacterized protein. (117 aa)
	APAF1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1228 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (443 aa)
	CASP9	Caspase 9; Belongs to the peptidase C14A family. (372 aa)
	TBC1D10A	TBC1 domain family member 10A. (508 aa)
	PERP	P53 apoptosis effector related to PMP22. (193 aa)
	ENSRBIP00000022247	Uncharacterized protein. (70 aa)
	ENSRBIP00000025248	Uncharacterized protein. (174 aa)
	FADD	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa)
	IFI16	Interferon gamma inducible protein 16. (729 aa)
	NLRP6	NLR family pyrin domain containing 6. (1041 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APAF1	BAK1	ENSRBIP00000005479	ENSRBIP00000037336	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	BCL2 antagonist/killer 1.	0.646
APAF1	CASP6	ENSRBIP00000005479	ENSRBIP00000009816	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 6; Belongs to the peptidase C14A family.	0.801
APAF1	CASP8	ENSRBIP00000005479	ENSRBIP00000042695	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 8; Belongs to the peptidase C14A family.	0.845
APAF1	CASP9	ENSRBIP00000005479	ENSRBIP00000012848	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Caspase 9; Belongs to the peptidase C14A family.	0.999
APAF1	ENSRBIP00000009112	ENSRBIP00000005479	ENSRBIP00000009112	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Uncharacterized protein.	0.414
APAF1	FADD	ENSRBIP00000005479	ENSRBIP00000026089	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.586
APAF1	LGMN	ENSRBIP00000005479	ENSRBIP00000030294	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Legumain.	0.414
BAD	BAK1	ENSRBIP00000041804	ENSRBIP00000037336	BCL2 associated agonist of cell death.	BCL2 antagonist/killer 1.	0.822
BAD	CASP9	ENSRBIP00000041804	ENSRBIP00000012848	BCL2 associated agonist of cell death.	Caspase 9; Belongs to the peptidase C14A family.	0.403
BAK1	APAF1	ENSRBIP00000037336	ENSRBIP00000005479	BCL2 antagonist/killer 1.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.646
BAK1	BAD	ENSRBIP00000037336	ENSRBIP00000041804	BCL2 antagonist/killer 1.	BCL2 associated agonist of cell death.	0.822
BAK1	CASP9	ENSRBIP00000037336	ENSRBIP00000012848	BCL2 antagonist/killer 1.	Caspase 9; Belongs to the peptidase C14A family.	0.483
BAK1	PYCARD	ENSRBIP00000037336	ENSRBIP00000038602	BCL2 antagonist/killer 1.	PYD and CARD domain containing.	0.580
CASP6	APAF1	ENSRBIP00000009816	ENSRBIP00000005479	Caspase 6; Belongs to the peptidase C14A family.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.801
CASP6	CASP8	ENSRBIP00000009816	ENSRBIP00000042695	Caspase 6; Belongs to the peptidase C14A family.	Caspase 8; Belongs to the peptidase C14A family.	0.981
CASP6	CASP9	ENSRBIP00000009816	ENSRBIP00000012848	Caspase 6; Belongs to the peptidase C14A family.	Caspase 9; Belongs to the peptidase C14A family.	0.955
CASP6	FADD	ENSRBIP00000009816	ENSRBIP00000026089	Caspase 6; Belongs to the peptidase C14A family.	FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling.	0.521
CASP8	APAF1	ENSRBIP00000042695	ENSRBIP00000005479	Caspase 8; Belongs to the peptidase C14A family.	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	0.845
CASP8	CASP6	ENSRBIP00000042695	ENSRBIP00000009816	Caspase 8; Belongs to the peptidase C14A family.	Caspase 6; Belongs to the peptidase C14A family.	0.981
CASP8	CASP9	ENSRBIP00000042695	ENSRBIP00000012848	Caspase 8; Belongs to the peptidase C14A family.	Caspase 9; Belongs to the peptidase C14A family.	0.599