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| | PDCD1LG2 | Programmed cell death 1 ligand 2. (248 aa) |
| | ZBTB7B | Zinc finger and BTB domain containing 7B. (539 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (668 aa) |
| | IL15 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | RUNX1 | RUNX family transcription factor 1. (264 aa) |
| | ENSRBIP00000001234 | Uncharacterized protein. (93 aa) |
| | SOCS1 | Suppressor of cytokine signaling 1. (215 aa) |
| | PNP | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (289 aa) |
| | RHOH | Ras homolog family member H. (191 aa) |
| | TNFRSF13C | TNF receptor superfamily member 13C. (140 aa) |
| | SOX4 | Transcription factor SOX. (475 aa) |
| | GPAM | Glycerol-3-phosphate acyltransferase 1, mitochondrial. (828 aa) |
| | ENSRBIP00000002079 | Uncharacterized protein. (202 aa) |
| | SRC | Tyrosine-protein kinase. (627 aa) |
| | NFKBID | NFKB inhibitor delta. (469 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (310 aa) |
| | SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1241 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1067 aa) |
| | ENSRBIP00000002430 | Ribosomal_S3_C domain-containing protein. (168 aa) |
| | HLX | H2.0 like homeobox. (494 aa) |
| | LOC108525356 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (235 aa) |
| | PPP3CA-2 | Uncharacterized protein. (70 aa) |
| | RASAL3 | RAS protein activator like 3. (992 aa) |
| | EFNB1 | Ephrin B1; Belongs to the ephrin family. (346 aa) |
| | CORO1A | Coronin; Belongs to the WD repeat coronin family. (461 aa) |
| | AP3D1 | AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1211 aa) |
| | RIPK2 | Receptor interacting serine/threonine kinase 2. (443 aa) |
| | SHB | SH2 domain containing adaptor protein B. (509 aa) |
| | IGFBP2 | Insulin like growth factor binding protein 2. (314 aa) |
| | SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (513 aa) |
| | ENSRBIP00000004373 | Ig-like domain-containing protein; Belongs to the MHC class I family. (391 aa) |
| | ENSRBIP00000004480 | Uncharacterized protein. (341 aa) |
| | CARD11 | Caspase recruitment domain family member 11. (1154 aa) |
| | EFNB3 | Ephrin B3; Belongs to the ephrin family. (340 aa) |
| | ETS1 | ETS proto-oncogene 1, transcription factor. (485 aa) |
| | EGR3 | Early growth response 3. (387 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (948 aa) |
| | RAG1 | V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1043 aa) |
| | CD274 | CD274 molecule. (290 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | CHST2 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (530 aa) |
| | THY1 | Thy-1 cell surface antigen. (161 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1035 aa) |
| | ENSRBIP00000006786 | Uncharacterized protein. (365 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | ENSRBIP00000006958 | TNF receptor-associated factor. (473 aa) |
| | FUT7 | Fucosyltransferase 7. (342 aa) |
| | VSIR | V-set immunoregulatory receptor. (359 aa) |
| | ENSRBIP00000007318 | Uncharacterized protein. (241 aa) |
| | IL1RL2 | Interleukin 1 receptor like 2. (652 aa) |
| | ABL1 | Tyrosine-protein kinase. (1149 aa) |
| | HLA-DMA | Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (290 aa) |
| | CSK | Tyrosine-protein kinase. (450 aa) |
| | SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) |
| | CD6 | CD6 molecule. (668 aa) |
| | CBFB | Core-binding factor subunit beta. (182 aa) |
| | IGF1 | Insulin like growth factor 1. (208 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | CD80 | CD80 molecule. (288 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (398 aa) |
| | ENSRBIP00000009767 | Uncharacterized protein. (546 aa) |
| | CD27 | CD27 molecule. (260 aa) |
| | AKT1 | AKT serine/threonine kinase 1. (486 aa) |
| | HAVCR2 | Hepatitis A virus cellular receptor 2. (294 aa) |
| | CD3E | CD3e molecule. (198 aa) |
| | ABL2 | Tyrosine-protein kinase. (1164 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (427 aa) |
| | LOC108544547 | Uncharacterized protein. (399 aa) |
| | ENSRBIP00000011569 | Uncharacterized protein. (176 aa) |
| | SIRPG | Signal regulatory protein gamma. (387 aa) |
| | TNFSF9 | TNF superfamily member 9; Belongs to the tumor necrosis factor family. (251 aa) |
| | CD276 | Uncharacterized protein. (299 aa) |
| | NFKBIZ | NFKB inhibitor zeta. (698 aa) |
| | CD160 | CD160 molecule. (232 aa) |
| | RARA | Retinoic acid receptor alpha. (478 aa) |
| | CD28 | CD28 molecule. (220 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1073 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | LOC108518721 | Ig-like domain-containing protein. (407 aa) |
| | CD83 | CD83 molecule. (205 aa) |
| | ICOS | Inducible T cell costimulator. (199 aa) |
| | ACTL6B | Actin like 6B; Belongs to the actin family. (440 aa) |
| | SLC7A1 | Solute carrier family 7 member 1. (629 aa) |
| | SPTA1 | Spectrin alpha, erythrocytic 1. (2490 aa) |
| | NCK1 | NCK adaptor protein 1. (371 aa) |
| | IL23R | Interleukin 23 receptor. (629 aa) |
| | HAS2 | Hyaluronan synthase 2. (552 aa) |
| | IL27RA | Interleukin 27 receptor subunit alpha. (724 aa) |
| | GATA3 | GATA binding protein 3. (444 aa) |
| | CD55 | CD55 molecule (Cromer blood group). (535 aa) |
| | LOC108519226 | Uncharacterized protein. (479 aa) |
| | ITGB2 | Integrin beta. (779 aa) |
| | RASGRP1 | RAS guanyl releasing protein 1. (841 aa) |
| | DOCK8 | Dedicator of cytokinesis 8; Belongs to the DOCK family. (2084 aa) |
| | IL7R | Interleukin 7 receptor. (459 aa) |
| | PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (754 aa) |
| | ADA | A_deaminase domain-containing protein. (443 aa) |
| | DHPS | Uncharacterized protein. (369 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | LOC108512973 | Ig-like domain-containing protein. (263 aa) |
| | LOC108521970 | WD_REPEATS_REGION domain-containing protein. (475 aa) |
| | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1107 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa) |
| | HLA-DQB1 | Ig-like domain-containing protein. (261 aa) |
| | ENSRBIP00000015630 | Uncharacterized protein. (49 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (674 aa) |
| | KITLG | Kit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (252 aa) |
| | SIRPD | Signal regulatory protein delta. (197 aa) |
| | MALT1 | MALT1 paracaspase. (811 aa) |
| | CD5 | CD5 molecule. (499 aa) |
| | HLA-DRA | Major histocompatibility complex, class II, DR alpha; Belongs to the MHC class II family. (254 aa) |
| | STAT5B | Signal transducer and activator of transcription. (768 aa) |
| | CD209 | CD209 molecule. (356 aa) |
| | IL4R | Interleukin 4 receptor. (825 aa) |
| | ENSRBIP00000016878 | Uncharacterized protein. (251 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1134 aa) |
| | IL2RG | Fibronectin type-III domain-containing protein. (369 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | CD86 | CD86 molecule. (329 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (269 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa) |
| | RELA | Uncharacterized protein. (282 aa) |
| | NFAT5 | Nuclear factor of activated T cells 5. (1442 aa) |
| | VCAM1 | Vascular cell adhesion molecule 1. (739 aa) |
| | HLA-DPA1 | Major histocompatibility complex, class II, DP alpha 1; Belongs to the MHC class II family. (260 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (755 aa) |
| | ENSRBIP00000019290 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (242 aa) |
| | MDK | Uncharacterized protein. (143 aa) |
| | IL12RB1 | Interleukin 12 receptor subunit beta 1. (652 aa) |
| | LOC108527746 | Uncharacterized protein. (511 aa) |
| | TNFSF4 | TNF superfamily member 4; Belongs to the tumor necrosis factor family. (183 aa) |
| | ENSRBIP00000019541 | Ig-like domain-containing protein. (264 aa) |
| | GP1BA | Glycoprotein Ib platelet subunit alpha. (599 aa) |
| | FOXP3 | Forkhead box P3. (456 aa) |
| | IL4I1 | Amine oxidase. (579 aa) |
| | LOC108519884 | Ig-like domain-containing protein. (266 aa) |
| | SLAMF1 | Signaling lymphocytic activation molecule family member 1. (357 aa) |
| | XBP1 | BZIP domain-containing protein. (380 aa) |
| | TNFSF13B | TNF superfamily member 13b; Belongs to the tumor necrosis factor family. (317 aa) |
| | ENSRBIP00000021702 | Uncharacterized protein. (144 aa) |
| | DNAJA3 | DnaJ heat shock protein family (Hsp40) member A3. (480 aa) |
| | ENSRBIP00000022247 | Uncharacterized protein. (70 aa) |
| | CD44 | CD44 molecule (Indian blood group). (742 aa) |
| | CD81 | CD81 molecule; Belongs to the tetraspanin (TM4SF) family. (252 aa) |
| | ENSRBIP00000022441 | Uncharacterized protein. (64 aa) |
| | ZBTB16 | Zinc finger and BTB domain containing 16. (673 aa) |
| | LOC108531166 | AIG1-type G domain-containing protein. (307 aa) |
| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (260 aa) |
| | AGER | Uncharacterized protein. (417 aa) |
| | SYK | Uncharacterized protein. (331 aa) |
| | SIRPA | Uncharacterized protein. (505 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa) |
| | TYK2 | Tyrosine-protein kinase. (1187 aa) |
| | IL23A | Interleukin 23 subunit alpha. (189 aa) |
| | CLECL1 | Uncharacterized protein. (162 aa) |
| | FAM49B | Family with sequence similarity 49 member B. (324 aa) |
| | AIF1 | Allograft inflammatory factor 1. (147 aa) |
| | SOX13 | SRY-box transcription factor 13. (604 aa) |
| | ENSRBIP00000024399 | Uncharacterized protein; Belongs to the tetraspanin (TM4SF) family. (124 aa) |
| | MYB | MYB proto-oncogene, transcription factor. (761 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3. (637 aa) |
| | VNN1 | Vanin 1. (513 aa) |
| | HLA-E | Major histocompatibility complex, class I, E; Belongs to the MHC class I family. (359 aa) |
| | TNFSF11 | Tumor necrosis factor ligand superfamily member. (317 aa) |
| | TNFSF14 | TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (217 aa) |
| | FCHO1 | FCH domain only 1. (843 aa) |
| | CCR7 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (375 aa) |
| | VTCN1 | V-set domain containing T cell activation inhibitor 1. (285 aa) |
| | EFNB2 | Ephrin B2; Belongs to the ephrin family. (312 aa) |
| | ELANE | Elastase, neutrophil expressed; Belongs to the peptidase S1 family. (265 aa) |
| | SASH3 | SAM and SH3 domain containing 3. (357 aa) |
| | ARID1A | AT-rich interaction domain 1A. (2225 aa) |
| | FADD | FAS-associated death domain protein; Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling. (208 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (702 aa) |
| | ENSRBIP00000026419 | Uncharacterized protein. (249 aa) |
| | IL18 | Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa) |
| | ZAP70 | Tyrosine-protein kinase. (619 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa) |
| | DUSP10 | Dual specificity phosphatase 10. (500 aa) |
| | ENSRBIP00000027432 | Ig-like domain-containing protein. (244 aa) |
| | JAK3 | Tyrosine-protein kinase. (1124 aa) |
| | IL7 | Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (171 aa) |
| | GLI3 | GLI family zinc finger 3. (1555 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | MAP3K8 | Mitogen-activated protein kinase kinase kinase 8. (466 aa) |
| | LOC108519885 | Ig-like domain-containing protein. (266 aa) |
| | SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1556 aa) |
| | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa) |
| | PHF10 | PHD finger protein 10. (494 aa) |
| | IL36B | Interleukin 36 beta. (164 aa) |
| | CCL19 | C-C motif chemokine. (98 aa) |
| | HHLA2 | HERV-H LTR-associating 2. (419 aa) |
| | HLA-DOB | Major histocompatibility complex, class II, DO beta. (273 aa) |
| | PBRM1 | Polybromo 1. (1676 aa) |
| | IL6ST | Uncharacterized protein. (330 aa) |
| | LGALS1 | Galectin. (135 aa) |
| | FLOT2 | Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (494 aa) |
| | PRKCQ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (706 aa) |
| | PTPN22 | Protein tyrosine phosphatase non-receptor type 22. (779 aa) |
| | TESPA1 | Thymocyte expressed, positive selection associated 1. (520 aa) |
| | LCK | Tyrosine-protein kinase. (518 aa) |
| | ENSRBIP00000031653 | Uncharacterized protein. (70 aa) |
| | IFNG | Interferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (159 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (501 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) |
| | ENSRBIP00000032719 | SH2 domain-containing protein. (203 aa) |
| | YES1 | Tyrosine-protein kinase. (480 aa) |
| | SELE | Selectin E. (610 aa) |
| | HLA-DPB1 | Major histocompatibility complex, class II, DP beta 1. (258 aa) |
| | LOC108516810 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (330 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa) |
| | ENSRBIP00000033881 | Uncharacterized protein. (61 aa) |
| | SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa) |
| | ENSRBIP00000034301 | Ribosomal_S3_C domain-containing protein. (253 aa) |
| | VAV1 | Vav guanine nucleotide exchange factor 1. (843 aa) |
| | NCK2 | Cytoplasmic protein. (380 aa) |
| | IHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa) |
| | RUNX3 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa) |
| | HLA-DOA | Major histocompatibility complex, class II, DO alpha; Belongs to the MHC class II family. (250 aa) |
| | BTN2A2 | Uncharacterized protein. (518 aa) |
| | ARID2 | AT-rich interaction domain 2. (1830 aa) |
| | CCDC88B | Coiled-coil domain containing 88B. (1537 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | LOC108524385 | Uncharacterized protein. (348 aa) |
| | BCL6 | BCL6 transcription repressor. (706 aa) |
| | ENSRBIP00000036977 | Protein kinase domain-containing protein. (68 aa) |
| | CD70 | CD70 molecule; Belongs to the tumor necrosis factor family. (194 aa) |
| | PRKCZ | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa) |
| | ENSRBIP00000037360 | KH type-2 domain-containing protein. (143 aa) |
| | ZP4 | Zona pellucida glycoprotein 4. (539 aa) |
| | TFRC | Transferrin receptor. (760 aa) |
| | SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa) |
| | CD74 | CD74 molecule. (294 aa) |
| | SKAP1 | Src kinase associated phosphoprotein 1. (397 aa) |
| | IL2 | Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa) |
| | ENSRBIP00000038500 | RHD domain-containing protein. (112 aa) |
| | ICOSLG | Uncharacterized protein. (302 aa) |
| | PYCARD | PYD and CARD domain containing. (195 aa) |
| | TMIGD2 | Transmembrane and immunoglobulin domain containing 2. (302 aa) |
| | IGF2 | Insulin like growth factor 2. (236 aa) |
| | PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (602 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1310 aa) |
| | ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (333 aa) |
| | CD1D | CD1d molecule. (337 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | DPP4 | Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (767 aa) |
| | TNFRSF14 | TNF receptor superfamily member 14. (283 aa) |
| | IL6 | Interleukin 6. (214 aa) |
| | BCL10 | BCL10 immune signaling adaptor. (233 aa) |
| | IL21 | Interleukin; Belongs to the IL-15/IL-21 family. (162 aa) |
| | SART1 | Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa) |
| | JAK2 | Tyrosine-protein kinase. (1083 aa) |
| | BAD | BCL2 associated agonist of cell death. (167 aa) |
| | IL12RB2 | Interleukin 12 receptor subunit beta 2. (817 aa) |
| | SELP | Selectin P. (829 aa) |
| | ARID1B | AT-rich interaction domain 1B. (1582 aa) |
| | EPHB6 | EPH receptor B6. (1018 aa) |
| | ENSRBIP00000042716 | A_deaminase domain-containing protein. (344 aa) |
| | GLI2 | GLI family zinc finger 2. (1581 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | VNN3 | Vanin 3. (273 aa) |
| | IL4 | Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Belongs to the IL-4/IL-13 family. (153 aa) |
