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| | EPC2 | Enhancer of polycomb homolog. (702 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (243 aa) |
| | PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) |
| | TRIM28 | Tripartite motif containing 28. (746 aa) |
| | INO80D | INO80 complex subunit D. (1028 aa) |
| | ENSRBIP00000043357 | Uncharacterized protein. (714 aa) |
| | POGZ | Pogo transposable element derived with ZNF domain. (1418 aa) |
| | RBBP8 | RB binding protein 8, endonuclease. (898 aa) |
| | LOC108529932 | FAM35_C domain-containing protein. (210 aa) |
| | WAS | WASP actin nucleation promoting factor. (455 aa) |
| | ARID1B | AT-rich interaction domain 1B. (1582 aa) |
| | SLF1 | SMC5-SMC6 complex localization factor 1. (1050 aa) |
| | PAXIP1 | PAX interacting protein 1. (1086 aa) |
| | ZNHIT1 | Zinc finger HIT-type containing 1. (154 aa) |
| | EP400 | E1A binding protein p400. (3059 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1818 aa) |
| | TRRAP | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3824 aa) |
| | BABAM1 | BRISC and BRCA1 A complex member 1. (329 aa) |
| | PARP9 | Poly(ADP-ribose) polymerase family member 9. (749 aa) |
| | SMCHD1 | Structural maintenance of chromosomes flexible hinge domain containing 1. (1944 aa) |
| | MEAF6 | Uncharacterized protein. (171 aa) |
| | INO80B | PAPA-1 domain-containing protein. (373 aa) |
| | YEATS4 | YEATS domain containing 4. (224 aa) |
| | SMARCD1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | ENSRBIP00000037360 | KH type-2 domain-containing protein. (143 aa) |
| | ENSRBIP00000037358 | DUF1725 domain-containing protein. (64 aa) |
| | PIAS4 | Protein inhibitor of activated STAT 4. (508 aa) |
| | FUS | FUS RNA binding protein. (522 aa) |
| | HELQ | Helicase, POLQ like. (1101 aa) |
| | ENSRBIP00000035711 | RAD51_interact domain-containing protein. (282 aa) |
| | ARID2 | AT-rich interaction domain 2. (1830 aa) |
| | BRCC3 | MPN domain-containing protein. (297 aa) |
| | ENSRBIP00000035213 | Uncharacterized protein; Belongs to the actin family. (362 aa) |
| | DHX9 | DExH-box helicase 9. (1275 aa) |
| | ENSRBIP00000034744 | Uncharacterized protein. (127 aa) |
| | DDX11 | DEAD/H-box helicase 11. (906 aa) |
| | ENSRBIP00000034301 | Ribosomal_S3_C domain-containing protein. (253 aa) |
| | SMARCE1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (411 aa) |
| | ENSRBIP00000033932 | LEDGF domain-containing protein. (228 aa) |
| | PARP3 | Poly [ADP-ribose] polymerase. (531 aa) |
| | BRD8 | Bromodomain containing 8. (1236 aa) |
| | ZNF385A | Zinc finger protein 385A. (414 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa) |
| | DMAP1 | DNA methyltransferase 1 associated protein 1. (467 aa) |
| | ACTR2 | Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa) |
| | CCDC117 | Coiled-coil domain containing 117. (278 aa) |
| | UIMC1 | Ubiquitin interaction motif containing 1. (719 aa) |
| | FOXM1 | Forkhead box M1. (654 aa) |
| | DTX3L | Deltex E3 ubiquitin ligase 3L. (744 aa) |
| | FANCB | FA complementation group B. (516 aa) |
| | SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (501 aa) |
| | ENSRBIP00000031407 | MRG domain-containing protein. (160 aa) |
| | FAM178B | Family with sequence similarity 178 member B. (679 aa) |
| | TTI1 | TELO2 interacting protein 1. (1089 aa) |
| | PBK | Protein kinase domain-containing protein. (322 aa) |
| | SKIL | SKI like proto-oncogene. (692 aa) |
| | ING3 | Inhibitor of growth protein. (418 aa) |
| | PBRM1 | Polybromo 1. (1676 aa) |
| | RNF168 | E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (571 aa) |
| | EYA3 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (543 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) |
| | PHF10 | PHD finger protein 10. (494 aa) |
| | TELO2 | Telomere maintenance 2. (836 aa) |
| | OOEP | Oocyte expressed protein. (149 aa) |
| | SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4. (1679 aa) |
| | SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2. (1556 aa) |
| | FBH1 | F-box DNA helicase 1. (1079 aa) |
| | TFPT | TCF3 fusion partner. (253 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (513 aa) |
| | KMT5B | Lysine methyltransferase 5B. (870 aa) |
| | ENSRBIP00000027876 | Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (353 aa) |
| | ACTR8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa) |
| | ABRAXAS1 | Abraxas 1, BRCA1 A complex subunit. (408 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2578 aa) |
| | SPIRE2 | Spire type actin nucleation factor 2. (668 aa) |
| | INO80E | INO80 complex subunit E. (244 aa) |
| | SHLD2 | FAM35_C domain-containing protein. (905 aa) |
| | FXR1 | FMR1 autosomal homolog 1. (588 aa) |
| | ARID1A | AT-rich interaction domain 1A. (2225 aa) |
| | ERCC8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (370 aa) |
| | KHDC3L | KH domain containing 3 like, subcortical maternal complex member. (217 aa) |
| | KMT5C | Lysine methyltransferase 5C. (461 aa) |
| | ACTL6A | Actin like 6A; Belongs to the actin family. (429 aa) |
| | SPIRE1 | Spire type actin nucleation factor 1. (739 aa) |
| | ENSRBIP00000024775 | Uncharacterized protein. (140 aa) |
| | MMS19 | MMS19 homolog, cytosolic iron-sulfur assembly component. (1030 aa) |
| | ENSRBIP00000024049 | EP400_N domain-containing protein. (391 aa) |
| | WRAP53 | WD repeat containing antisense to TP53. (549 aa) |
| | TMEM161A | Transmembrane protein 161A. (479 aa) |
| | NACC2 | NACC family member 2. (571 aa) |
| | HDAC10 | Histone deacetylase 10. (673 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1484 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | MRGBP | MRG domain binding protein. (179 aa) |
| | ENSRBIP00000022441 | Uncharacterized protein. (64 aa) |
| | UBE2V2 | Ubiquitin conjugating enzyme E2 V2. (144 aa) |
| | TTI2 | TELO2 interacting protein 2. (511 aa) |
| | ENSRBIP00000021372 | Lyase_1 domain-containing protein. (175 aa) |
| | FXR2 | FMR1 autosomal homolog 2. (673 aa) |
| | ENSRBIP00000020891 | Uncharacterized protein. (64 aa) |
| | RPL26 | Ribosomal protein L26. (145 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3026 aa) |
| | ZCWPW1 | Zinc finger CW-type and PWWP domain containing 1. (645 aa) |
| | ENSRBIP00000019290 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (242 aa) |
| | SPIDR | DUF4503 domain-containing protein. (397 aa) |
| | ENSRBIP00000019157 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (78 aa) |
| | EEF1E1 | GST C-terminal domain-containing protein. (174 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | BABAM2 | BRISC and BRCA1 A complex member 2. (415 aa) |
| | MAP3K20 | Mitogen-activated protein kinase kinase kinase 20. (800 aa) |
| | FH | Fumarate hydratase. (451 aa) |
| | LOC108526377 | MRG domain-containing protein. (291 aa) |
| | WDR48 | WD repeat domain 48. (644 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (390 aa) |
| | BCL7C | BAF chromatin remodeling complex subunit BCL7C. (242 aa) |
| | MBTD1 | Mbt domain containing 1. (722 aa) |
| | EPC1 | Enhancer of polycomb homolog. (836 aa) |
| | INO80 | INO80 complex ATPase subunit. (1555 aa) |
| | ANKLE1 | Ankyrin repeat and LEM domain containing 1. (669 aa) |
| | SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1. (1107 aa) |
| | FAM168A | Family with sequence similarity 168 member A. (244 aa) |
| | EYA2 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (530 aa) |
| | FMN2 | Formin 2. (1620 aa) |
| | SETMAR | SET domain and mariner transposase fusion gene. (684 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4128 aa) |
| | ENSRBIP00000013617 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (245 aa) |
| | ACTL6B | Actin like 6B; Belongs to the actin family. (440 aa) |
| | NSMCE1 | NSE1 homolog, SMC5-SMC6 complex component. (303 aa) |
| | PYHIN1 | Pyrin and HIN domain family member 1. (492 aa) |
| | BCLAF1 | BCL2 associated transcription factor 1. (921 aa) |
| | ENSRBIP00000011806 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa) |
| | ENSRBIP00000011440 | HELICc2 domain-containing protein. (117 aa) |
| | SIRT6 | Sirtuin 6. (355 aa) |
| | RPL26L1 | Ribosomal protein L26 like 1. (145 aa) |
| | ENSRBIP00000011112 | Uncharacterized protein. (159 aa) |
| | CEBPG | CCAAT enhancer binding protein gamma. (150 aa) |
| | ING4 | Inhibitor of growth protein. (252 aa) |
| | LOC108538182 | MPN domain-containing protein. (237 aa) |
| | HDGFL2 | HDGF like 2. (575 aa) |
| | SIRT1 | Sirtuin 1. (731 aa) |
| | SPRED1 | Sprouty related EVH1 domain containing 1. (444 aa) |
| | CCAR2 | Cell cycle and apoptosis regulator 2. (923 aa) |
| | MCRS1 | Microspherule protein 1. (475 aa) |
| | SMARCB1 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa) |
| | ENSRBIP00000008159 | MOEP19 domain-containing protein. (125 aa) |
| | VPS72 | Vacuolar protein sorting 72 homolog. (364 aa) |
| | NFRKB | Nuclear factor related to kappaB binding protein. (1311 aa) |
| | LOC108526191 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (112 aa) |
| | TIGAR | TP53 induced glycolysis regulatory phosphatase. (316 aa) |
| | SLF2 | SMC5-SMC6 complex localization factor 2. (1163 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | DPF2 | Double PHD fingers 2. (405 aa) |
| | MAD2L2 | Mitotic arrest deficient 2 like 2. (218 aa) |
| | ENSRBIP00000006786 | Uncharacterized protein. (365 aa) |
| | BCL7B | BAF chromatin remodeling complex subunit BCL7B. (202 aa) |
| | MGMT | Methyltransf_1N domain-containing protein. (122 aa) |
| | SHLD1 | Shieldin complex subunit 1. (254 aa) |
| | LOC108520651 | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | EYA4 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (645 aa) |
| | NKX3-1 | NK3 homeobox 1. (230 aa) |
| | LOC108526263 | KOW domain-containing protein. (145 aa) |
| | ANKRD1 | Ankyrin repeat domain 1. (319 aa) |
| | UBE2NL | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa) |
| | LOC108514958 | Protein kinase domain-containing protein. (323 aa) |
| | ENSRBIP00000004795 | DUF4502 domain-containing protein. (197 aa) |
| | DPF3 | Double PHD fingers 3. (426 aa) |
| | PNKP | Polynucleotide kinase 3'-phosphatase. (521 aa) |
| | ENSRBIP00000004480 | Uncharacterized protein. (341 aa) |
| | SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2. (513 aa) |
| | EYA1 | Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa) |
| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (468 aa) |
| | ENSRBIP00000003960 | KOW domain-containing protein. (137 aa) |
| | ACTB | Actin beta. (379 aa) |
| | NPAS2 | Neuronal PAS domain protein 2. (824 aa) |
| | TIMELESS | Timeless circadian regulator. (1208 aa) |
| | ENSRBIP00000002430 | Ribosomal_S3_C domain-containing protein. (168 aa) |
| | SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2. (1241 aa) |
| | ENSRBIP00000002260 | Btz domain-containing protein. (803 aa) |
| | MRNIP | MRN complex interacting protein. (362 aa) |
| | FGF10 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | UCHL5 | Ubiquitin carboxyl-terminal hydrolase. (369 aa) |
| | PRKCG | Protein kinase C. (726 aa) |
| | RIF1 | Replication timing regulatory factor 1. (2444 aa) |
| | MFSD11 | Major facilitator superfamily domain containing 11. (449 aa) |
| | PLA2R1 | Phospholipase A2 receptor 1. (1445 aa) |
| | DPF1 | Double PHD fingers 1. (344 aa) |
| | ENSRBIP00000000149 | Uncharacterized protein. (163 aa) |
