(45 nodes) RmlC-like jelly roll fold network (Rhinopithecus bieti)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SLC9C2	Solute carrier family 9 member C2 (putative). (1115 aa)
	PRKAR2A	Protein kinase cAMP-dependent type II regulatory subunit alpha. (376 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2. (1474 aa)
	HCN4	Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1225 aa)
	KCNH8	Potassium voltage-gated channel subfamily H member 8. (1069 aa)
	CNGB3	Cyclic nucleotide gated channel subunit beta 3. (809 aa)
	ADO	2-aminoethanethiol dioxygenase. (270 aa)
	GGCX	Gamma-glutamyl carboxylase. (758 aa)
	SLC9C1	Solute carrier family 9 member C1. (1172 aa)
	CNNM4	Cyclin and CBS domain divalent metal cation transport mediator 4. (758 aa)
	KCNH6	Potassium voltage-gated channel subfamily H member 6. (994 aa)
	HSPBAP1	HSPB1 associated protein 1. (489 aa)
	CENPC	Centromere protein C. (956 aa)
	CNGA4	Cyclic nucleotide gated channel subunit alpha 4. (605 aa)
	HCN2	Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (490 aa)
	KCNH1	Potassium voltage-gated channel subfamily H member 1. (962 aa)
	KCNH7	Potassium voltage-gated channel subfamily H member 7. (1196 aa)
	CNBD1	Cyclic nucleotide binding domain containing 1. (346 aa)
	RAPGEF6	Uncharacterized protein. (1409 aa)
	KCNH3	Potassium voltage-gated channel subfamily H member 3. (1083 aa)
	CNBD2	Cyclic nucleotide binding domain containing 2. (610 aa)
	JMJD7	Jumonji domain containing 7. (316 aa)
	PRKG2	cGMP-dependent protein kinase. (725 aa)
	HAAO	3-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate; Belongs to the 3-HAO family. (286 aa)
	PRKAR2B	Protein kinase cAMP-dependent type II regulatory subunit beta. (412 aa)
	PNPLA6	Patatin like phospholipase domain containing 6. (1359 aa)
	CNGA1	Cyclic nucleotide gated channel subunit alpha 1. (745 aa)
	ADI1	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Belongs to the acireductone dioxygenase (ARD) family. (179 aa)
	PNPLA7	Patatin like phospholipase domain containing 7. (1420 aa)
	KCNH2	Potassium voltage-gated channel subfamily H member 2. (1152 aa)
	ENSRBIP00000041597	Cyclic nucleotide-binding domain-containing protein. (199 aa)
	BVES	Blood vessel epicardial substance. (360 aa)
	HIF1AN	Hypoxia inducible factor 1 subunit alpha inhibitor. (349 aa)
	KCNH4	Potassium voltage-gated channel subfamily H member 4. (1017 aa)
	HCN3	Hyperpolarization activated cyclic nucleotide gated potassium channel 3. (774 aa)
	RAPGEF4	Rap guanine nucleotide exchange factor 4. (882 aa)
	CDO1	Cysteine dioxygenase. (200 aa)
	PRKAR1B	Protein kinase cAMP-dependent type I regulatory subunit beta. (452 aa)
	CNGB1	Cyclic nucleotide gated channel subunit beta 1. (1236 aa)
	HGD	Homogentisate 1,2-dioxygenase. (445 aa)
	CNGA3	Cyclic nucleotide gated channel subunit alpha 3. (694 aa)
	MPI	Mannose-6-phosphate isomerase. (403 aa)
	PIR	Pirin; Belongs to the pirin family. (264 aa)
	PRKAR1A	Protein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
	CNGA2	Cyclic nucleotide gated channel subunit alpha 2. (664 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADO	CDO1	ENSRBIP00000007370	ENSRBIP00000037022	2-aminoethanethiol dioxygenase.	Cysteine dioxygenase.	0.681
CDO1	ADO	ENSRBIP00000037022	ENSRBIP00000007370	Cysteine dioxygenase.	2-aminoethanethiol dioxygenase.	0.681
CNGA1	CNGB1	ENSRBIP00000018856	ENSRBIP00000036020	Cyclic nucleotide gated channel subunit alpha 1.	Cyclic nucleotide gated channel subunit beta 1.	0.998
CNGA1	CNGB3	ENSRBIP00000018856	ENSRBIP00000007289	Cyclic nucleotide gated channel subunit alpha 1.	Cyclic nucleotide gated channel subunit beta 3.	0.956
CNGA2	CNGA3	ENSRBIP00000001225	ENSRBIP00000035284	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide gated channel subunit alpha 3.	0.450
CNGA2	CNGA4	ENSRBIP00000001225	ENSRBIP00000032797	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide gated channel subunit alpha 4.	0.894
CNGA2	CNGB1	ENSRBIP00000001225	ENSRBIP00000036020	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide gated channel subunit beta 1.	0.994
CNGA2	CNGB3	ENSRBIP00000001225	ENSRBIP00000007289	Cyclic nucleotide gated channel subunit alpha 2.	Cyclic nucleotide gated channel subunit beta 3.	0.875
CNGA3	CNGA2	ENSRBIP00000035284	ENSRBIP00000001225	Cyclic nucleotide gated channel subunit alpha 3.	Cyclic nucleotide gated channel subunit alpha 2.	0.450
CNGA3	CNGB1	ENSRBIP00000035284	ENSRBIP00000036020	Cyclic nucleotide gated channel subunit alpha 3.	Cyclic nucleotide gated channel subunit beta 1.	0.876
CNGA3	CNGB3	ENSRBIP00000035284	ENSRBIP00000007289	Cyclic nucleotide gated channel subunit alpha 3.	Cyclic nucleotide gated channel subunit beta 3.	0.963
CNGA4	CNGA2	ENSRBIP00000032797	ENSRBIP00000001225	Cyclic nucleotide gated channel subunit alpha 4.	Cyclic nucleotide gated channel subunit alpha 2.	0.894
CNGA4	CNGB1	ENSRBIP00000032797	ENSRBIP00000036020	Cyclic nucleotide gated channel subunit alpha 4.	Cyclic nucleotide gated channel subunit beta 1.	0.944
CNGA4	CNGB3	ENSRBIP00000032797	ENSRBIP00000007289	Cyclic nucleotide gated channel subunit alpha 4.	Cyclic nucleotide gated channel subunit beta 3.	0.875
CNGB1	CNGA1	ENSRBIP00000036020	ENSRBIP00000018856	Cyclic nucleotide gated channel subunit beta 1.	Cyclic nucleotide gated channel subunit alpha 1.	0.998
CNGB1	CNGA2	ENSRBIP00000036020	ENSRBIP00000001225	Cyclic nucleotide gated channel subunit beta 1.	Cyclic nucleotide gated channel subunit alpha 2.	0.994
CNGB1	CNGA3	ENSRBIP00000036020	ENSRBIP00000035284	Cyclic nucleotide gated channel subunit beta 1.	Cyclic nucleotide gated channel subunit alpha 3.	0.876
CNGB1	CNGA4	ENSRBIP00000036020	ENSRBIP00000032797	Cyclic nucleotide gated channel subunit beta 1.	Cyclic nucleotide gated channel subunit alpha 4.	0.944
CNGB3	CNGA1	ENSRBIP00000007289	ENSRBIP00000018856	Cyclic nucleotide gated channel subunit beta 3.	Cyclic nucleotide gated channel subunit alpha 1.	0.956
CNGB3	CNGA2	ENSRBIP00000007289	ENSRBIP00000001225	Cyclic nucleotide gated channel subunit beta 3.	Cyclic nucleotide gated channel subunit alpha 2.	0.875