140 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ATG16L1	Autophagy related 16 like 1. (624 aa)
	LOC108541986	WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (380 aa)
	WDR47	WD repeat domain 47. (901 aa)
	ENSRBIP00000041517	WD_REPEATS_REGION domain-containing protein. (478 aa)
	COP1	COP1 E3 ubiquitin ligase. (725 aa)
	ENSRBIP00000043728	Uncharacterized protein. (394 aa)
	FBXW10	WD_REPEATS_REGION domain-containing protein. (1038 aa)
	POC1B	POC1 centriolar protein B. (457 aa)
	WDR1	WD repeat domain 1. (608 aa)
	DCAF12	DDB1 and CUL4 associated factor 12. (453 aa)
	BTRC	Beta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
	DCAF7	DDB1 and CUL4 associated factor 7. (342 aa)
	CDC40	Cell division cycle 40. (625 aa)
	RBBP4	WD_REPEATS_REGION domain-containing protein. (419 aa)
	CFAP44	Cilia and flagella associated protein 44. (1853 aa)
	NEDD1	NEDD1 gamma-tubulin ring complex targeting factor. (659 aa)
	KIF21B	Kinesin family member 21B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1637 aa)
	WDR88	WD repeat domain 88. (450 aa)
	LYST	Lysosomal trafficking regulator. (3787 aa)
	MLST8	MTOR associated protein, LST8 homolog. (335 aa)
	CHAF1B	Chromatin assembly factor 1 subunit B. (473 aa)
	CORO1A	Coronin; Belongs to the WD repeat coronin family. (461 aa)
	WDR5B	WD repeat domain 5B. (330 aa)
	WDR7	WD repeat domain 7. (1444 aa)
	PHIP	Pleckstrin homology domain interacting protein. (1815 aa)
	APAF1	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. (1228 aa)
	DPH7	Diphthamide biosynthesis 7. (511 aa)
	TBL1XR1	Transducin beta like 1 X-linked receptor 1. (514 aa)
	WDR12	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (423 aa)
	KIF21A	Kinesin family member 21A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1637 aa)
	GNB4	G protein subunit beta 4. (340 aa)
	BOP1	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (746 aa)
	RACK1	Receptor for activated C kinase 1. (330 aa)
	SCAP	SREBF chaperone. (1469 aa)
	SMU1	SMU1 DNA replication regulator and spliceosomal factor. (513 aa)
	SNRNP40	Small nuclear ribonucleoprotein U5 subunit 40. (401 aa)
	WDR83	WD repeat domain 83. (346 aa)
	BRWD1	Bromodomain and WD repeat domain containing 1. (2281 aa)
	WDR37	WD repeat domain 37. (485 aa)
	TBL1X	Transducin beta like 1 X-linked. (586 aa)
	TLE2	TLE family member 2, transcriptional corepressor. (769 aa)
	RRP9	Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein. (474 aa)
	TRAF7	TNF receptor associated factor 7. (670 aa)
	COPA	Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1224 aa)
	WDR53	WD repeat domain 53. (409 aa)
	NUP37	Nucleoporin 37. (326 aa)
	CORO1C	Coronin; Belongs to the WD repeat coronin family. (527 aa)
	WDR11	WD repeat domain 11. (1224 aa)
	DAW1	WD_REPEATS_REGION domain-containing protein. (274 aa)
	WDR5	WD repeat domain 5. (334 aa)
	TLE1	TLE family member 1, transcriptional corepressor. (770 aa)
	STRN4	Striatin 4. (672 aa)
	LLGL1	LLGL scribble cell polarity complex component 1. (1042 aa)
	UTP15	UTP15 small subunit processome component. (488 aa)
	PEX7	Peroxisomal biogenesis factor 7. (323 aa)
	TLE4	TLE family member 4, transcriptional corepressor. (799 aa)
	FBXW2	Uncharacterized protein. (452 aa)
	LOC108521970	WD_REPEATS_REGION domain-containing protein. (475 aa)
	POC1A	POC1 centriolar protein A. (369 aa)
	WDR61	WD repeat domain 61. (305 aa)
	RAE1	Ribonucleic acid export 1. (368 aa)
	DCAF13	DDB1 and CUL4 associated factor 13. (579 aa)
	WDFY4	WDFY family member 4. (3176 aa)
	NUP43	WD_REPEATS_REGION domain-containing protein. (380 aa)
	GNB3	G protein subunit beta 3. (340 aa)
	WDR48	WD repeat domain 48. (644 aa)
	TBL3	Transducin beta like 3. (795 aa)
	GTF3C2	General transcription factor IIIC subunit 2. (911 aa)
	ATG16L2	Autophagy related 16 like 2. (619 aa)
	WDR77	WD repeat domain 77. (342 aa)
	THOC6	THO complex 6. (341 aa)
	CDC20B	Cell division cycle 20B. (519 aa)
	PAK1IP1	PAK1 interacting protein 1. (392 aa)
	STRN3	Striatin 3. (797 aa)
	GRWD1	Glutamate rich WD repeat containing 1. (445 aa)
	TAF5L	TATA-box binding protein associated factor 5 like. (589 aa)
	PWP2	Uncharacterized protein. (918 aa)
	CORO6	Coronin; Belongs to the WD repeat coronin family. (472 aa)
	PWP1	PWP1 homolog, endonuclein. (501 aa)
	NLE1	Notchless homolog 1. (514 aa)
	HERC1	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4758 aa)
	WDR24	WD repeat domain 24. (905 aa)
	STRN	Striatin. (751 aa)
	CORO2B	Coronin; Belongs to the WD repeat coronin family. (492 aa)
	WDR86	WD repeat domain 86. (466 aa)
	WDR72	WD repeat domain 72. (664 aa)
	LOC108524713	Uncharacterized protein. (340 aa)
	FBXW7	F-box and WD repeat domain containing 7. (707 aa)
	DDB2	Damage specific DNA binding protein 2. (427 aa)
	WDFY1	Uncharacterized protein. (405 aa)
	WDHD1	WD repeat and HMG-box DNA binding protein 1. (1123 aa)
	PRPF19	Pre-mRNA processing factor 19. (518 aa)
	CORO2A	Coronin; Belongs to the WD repeat coronin family. (525 aa)
	EIF3I	Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (326 aa)
	ERCC8	ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (370 aa)
	WDFY3	WD repeat and FYVE domain containing 3. (3516 aa)
	LRWD1	Leucine rich repeats and WD repeat domain containing 1. (681 aa)
	FBXW9	F-box and WD repeat domain containing 9. (458 aa)
	RBBP7	RB binding protein 7, chromatin remodeling factor. (458 aa)
	WSB1	WD repeat and SOCS box containing 1. (421 aa)
	PAM16	Coronin; Belongs to the WD repeat coronin family. (1031 aa)
	LOC108541991	WD_REPEATS_REGION domain-containing protein. (222 aa)
	WDFY2	Uncharacterized protein. (176 aa)
	WDR17	WD repeat domain 17. (1322 aa)
	FBXW11	F-box and WD repeat domain containing 11. (522 aa)
	SEC31B	SEC31 homolog B, COPII coat complex component. (1176 aa)
	WDR3	WD repeat domain 3. (972 aa)
	KATNB1	Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (655 aa)
	ENSRBIP00000031680	WD_REPEATS_REGION domain-containing protein. (408 aa)
	EIPR1	EARP complex and GARP complex interacting protein 1. (387 aa)
	DTL	Denticleless E3 ubiquitin protein ligase homolog. (730 aa)
	UTP18	UTP18 small subunit processome component. (585 aa)
	GNB1	G protein subunit beta 1. (340 aa)
	WDR49	WD repeat domain 49. (613 aa)
	PRPF4	Pre-mRNA processing factor 4. (543 aa)
	GEMIN5	Gem nuclear organelle associated protein 5. (1507 aa)
	FZR1	Fizzy and cell division cycle 20 related 1. (496 aa)
	AAAS	Aladin WD repeat nucleoporin. (546 aa)
	WDR36	WD repeat domain 36. (922 aa)
	WDR41	WD repeat domain 41. (459 aa)
	GNB5	G protein subunit beta 5. (403 aa)
	STXBP5L	Syntaxin binding protein 5 like. (1180 aa)
	PLRG1	Pleiotropic regulator 1. (514 aa)
	ENSRBIP00000035529	WD_REPEATS_REGION domain-containing protein. (235 aa)
	WDR31	WD repeat domain 31. (367 aa)
	CFAP52	Cilia and flagella associated protein 52. (620 aa)
	ENSRBIP00000036162	WD_REPEATS_REGION domain-containing protein. (399 aa)
	PAFAH1B1	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (410 aa)
	ENSRBIP00000037014	WD_REPEATS_REGION domain-containing protein. (370 aa)
	AAMP	Angio associated migratory cell protein. (434 aa)
	WDR38	WD repeat domain 38. (314 aa)
	CSTF1	Cleavage stimulation factor subunit 1. (431 aa)
	WDSUB1	WD repeat, sterile alpha motif and U-box domain containing 1. (476 aa)
	WSB2	Uncharacterized protein. (411 aa)
	EED	Embryonic ectoderm development. (466 aa)
	CIAO1	Probable cytosolic iron-sulfur protein assembly protein CIAO1; Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation; Belongs to the WD repeat CIA1 family. (339 aa)
	EML5	EMAP like 5. (1954 aa)
	EFCAB8	EF-hand calcium binding domain 8. (1288 aa)
	CORO1B	Coronin; Belongs to the WD repeat coronin family. (489 aa)
	TLE3	TLE family member 3, transcriptional corepressor. (778 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AAAS	GEMIN5	ENSRBIP00000033916	ENSRBIP00000033236	Aladin WD repeat nucleoporin.	Gem nuclear organelle associated protein 5.	0.453
AAAS	NUP37	ENSRBIP00000033916	ENSRBIP00000011711	Aladin WD repeat nucleoporin.	Nucleoporin 37.	0.875
AAAS	NUP43	ENSRBIP00000033916	ENSRBIP00000017533	Aladin WD repeat nucleoporin.	WD_REPEATS_REGION domain-containing protein.	0.875
AAAS	RAE1	ENSRBIP00000033916	ENSRBIP00000015867	Aladin WD repeat nucleoporin.	Ribonucleic acid export 1.	0.920
AAMP	BOP1	ENSRBIP00000037071	ENSRBIP00000007316	Angio associated migratory cell protein.	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.676
AAMP	GRWD1	ENSRBIP00000037071	ENSRBIP00000020299	Angio associated migratory cell protein.	Glutamate rich WD repeat containing 1.	0.927
AAMP	NLE1	ENSRBIP00000037071	ENSRBIP00000022208	Angio associated migratory cell protein.	Notchless homolog 1.	0.568
AAMP	PAK1IP1	ENSRBIP00000037071	ENSRBIP00000020226	Angio associated migratory cell protein.	PAK1 interacting protein 1.	0.443
AAMP	PWP2	ENSRBIP00000037071	ENSRBIP00000020789	Angio associated migratory cell protein.	Uncharacterized protein.	0.466
AAMP	TBL3	ENSRBIP00000037071	ENSRBIP00000017970	Angio associated migratory cell protein.	Transducin beta like 3.	0.725
AAMP	UTP18	ENSRBIP00000037071	ENSRBIP00000032146	Angio associated migratory cell protein.	UTP18 small subunit processome component.	0.736
AAMP	WDR12	ENSRBIP00000037071	ENSRBIP00000006381	Angio associated migratory cell protein.	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.602
AAMP	WDR3	ENSRBIP00000037071	ENSRBIP00000030610	Angio associated migratory cell protein.	WD repeat domain 3.	0.450
AAMP	WDR36	ENSRBIP00000037071	ENSRBIP00000034162	Angio associated migratory cell protein.	WD repeat domain 36.	0.565
APAF1	DCAF7	ENSRBIP00000005479	ENSRBIP00000000701	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	DDB1 and CUL4 associated factor 7.	0.455
APAF1	DDB2	ENSRBIP00000005479	ENSRBIP00000024461	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Damage specific DNA binding protein 2.	0.467
APAF1	DTL	ENSRBIP00000005479	ENSRBIP00000031981	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Denticleless E3 ubiquitin protein ligase homolog.	0.550
APAF1	ERCC8	ENSRBIP00000005479	ENSRBIP00000025822	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	ERCC excision repair 8, CSA ubiquitin ligase complex subunit.	0.494
APAF1	RACK1	ENSRBIP00000005479	ENSRBIP00000007491	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	Receptor for activated C kinase 1.	0.437
APAF1	WDR31	ENSRBIP00000005479	ENSRBIP00000035549	Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.	WD repeat domain 31.	0.469