(17 nodes) Proteinase inhibitor I2, Kunitz, conserved site network (Rhinopithecus bieti)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PAPLN	Papilin, proteoglycan like sulfated glycoprotein. (1266 aa)
	WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (502 aa)
	SPINT4	Serine peptidase inhibitor, Kunitz type 4. (99 aa)
	LOC108533352	Uncharacterized protein. (161 aa)
	AMBP	Alpha-1-microglobulin/bikunin precursor. (372 aa)
	SPINT3	Serine peptidase inhibitor, Kunitz type 3. (89 aa)
	WFDC8	WAP four-disulfide core domain 8. (241 aa)
	COL28A1	Collagen type XXVIII alpha 1 chain. (1124 aa)
	TFPI	Tissue factor pathway inhibitor. (208 aa)
	COL6A3	Collagen type VI alpha 3 chain. (3172 aa)
	COL7A1	Collagen type VII alpha 1 chain. (2719 aa)
	TFPI2	Tissue factor pathway inhibitor. (235 aa)
	WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa)
	SPINT1	Serine peptidase inhibitor, Kunitz type 1. (530 aa)
	APLP2	Amyloid beta precursor like protein 2. (738 aa)
	APP	Amyloid beta precursor protein. (770 aa)
	SPINT2	Serine peptidase inhibitor, Kunitz type 2. (252 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APLP2	APP	ENSRBIP00000033427	ENSRBIP00000038205	Amyloid beta precursor like protein 2.	Amyloid beta precursor protein.	0.567
APP	APLP2	ENSRBIP00000038205	ENSRBIP00000033427	Amyloid beta precursor protein.	Amyloid beta precursor like protein 2.	0.567
APP	SPINT2	ENSRBIP00000038205	ENSRBIP00000041336	Amyloid beta precursor protein.	Serine peptidase inhibitor, Kunitz type 2.	0.408
LOC108533352	SPINT4	ENSRBIP00000006200	ENSRBIP00000003801	Uncharacterized protein.	Serine peptidase inhibitor, Kunitz type 4.	0.567
SPINT2	APP	ENSRBIP00000041336	ENSRBIP00000038205	Serine peptidase inhibitor, Kunitz type 2.	Amyloid beta precursor protein.	0.408
SPINT2	SPINT4	ENSRBIP00000041336	ENSRBIP00000003801	Serine peptidase inhibitor, Kunitz type 2.	Serine peptidase inhibitor, Kunitz type 4.	0.446
SPINT4	LOC108533352	ENSRBIP00000003801	ENSRBIP00000006200	Serine peptidase inhibitor, Kunitz type 4.	Uncharacterized protein.	0.567
SPINT4	SPINT2	ENSRBIP00000003801	ENSRBIP00000041336	Serine peptidase inhibitor, Kunitz type 4.	Serine peptidase inhibitor, Kunitz type 2.	0.446
SPINT4	WFDC8	ENSRBIP00000003801	ENSRBIP00000015687	Serine peptidase inhibitor, Kunitz type 4.	WAP four-disulfide core domain 8.	0.576
WFDC8	SPINT4	ENSRBIP00000015687	ENSRBIP00000003801	WAP four-disulfide core domain 8.	Serine peptidase inhibitor, Kunitz type 4.	0.576