STRINGSTRING
ADCY8 ADCY8 ADCY5 ADCY5 ENSRBIP00000034184 ENSRBIP00000034184 CREB1 CREB1 GNG8 GNG8 GNB1 GNB1 THAP6 THAP6 GNG12 GNG12 ENSRBIP00000030120 ENSRBIP00000030120 GNAI2 GNAI2 PDE1A PDE1A ENSRBIP00000029999 ENSRBIP00000029999 ENSRBIP00000029215 ENSRBIP00000029215 PPP1R1B PPP1R1B MAPK1 MAPK1 GNG3 GNG3 CNBD2 CNBD2 GNA15 GNA15 ENSRBIP00000025613 ENSRBIP00000025613 GRK2 GRK2 PDE4A PDE4A CDK5 CDK5 PRKACB PRKACB GNB5 GNB5 ADCY1 ADCY1 GNAL GNAL GNAQ GNAQ PRKAR1B PRKAR1B GNGT2 GNGT2 PLCB2 PLCB2 CAMK2G CAMK2G PLCB4 PLCB4 PDE4B PDE4B GNG10 GNG10 NBEA NBEA GNAI3 GNAI3 PDE4D PDE4D PPP1CA PPP1CA ITPR3 ITPR3 LRBA LRBA CAMKK2 CAMKK2 PPP2CA PPP2CA ADCY2 ADCY2 LOC108520721 LOC108520721 CAMK2A CAMK2A PLCB3 PLCB3 PRKAR2B PRKAR2B ITPR1 ITPR1 PRKCD PRKCD ADCY4 ADCY4 ITPR2 ITPR2 GNG2 GNG2 CAMK4 CAMK4 ADCY3 ADCY3 ADCY9 ADCY9 ENSRBIP00000020927 ENSRBIP00000020927 PRKCA PRKCA THAP7 THAP7 LOC108522831 LOC108522831 PDYN PDYN GNG11 GNG11 THAP1 THAP1 ENSRBIP00000019086 ENSRBIP00000019086 GNG5 GNG5 GNG4 GNG4 GNB3 GNB3 AHCYL1 AHCYL1 GNB2 GNB2 PPP2CB PPP2CB PTRHD1 PTRHD1 ADCY7 ADCY7 KPNA2 KPNA2 PLA2G4A PLA2G4A GNAI1 GNAI1 PRKACA PRKACA PRKX PRKX ENSRBIP00000013012 ENSRBIP00000013012 ENSRBIP00000011770 ENSRBIP00000011770 GNAT3 GNAT3 PPP3CC PPP3CC PDE1C PDE1C GNG13 GNG13 GNG7 GNG7 PPP2R1A PPP2R1A LOC108534220 LOC108534220 ENSRBIP00000009458 ENSRBIP00000009458 GNA14 GNA14 CAMK2D CAMK2D PPP2R1B PPP2R1B ENSRBIP00000007423 ENSRBIP00000007423 PLCB1 PLCB1 DCLK1 DCLK1 PPP2R5D PPP2R5D GNB4 GNB4 ENSRBIP00000006659 ENSRBIP00000006659 ADCY6 ADCY6 GNA11 GNA11 PPP3CA-2 PPP3CA-2 PRKAR2A PRKAR2A POMC POMC ENSRBIP00000002474 ENSRBIP00000002474 PPP3CB PPP3CB PPP3CA PPP3CA ENSRBIP00000001234 ENSRBIP00000001234 PRKCG PRKCG PPP3R1 PPP3R1 PDE1B PDE1B PRKAR1A PRKAR1A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ADCY8Adenylate cyclase 8; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (657 aa)
ADCY5Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1085 aa)
ENSRBIP00000034184G protein gamma domain-containing protein. (68 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
GNB1G protein subunit beta 1. (340 aa)
THAP6THAP domain containing 6. (221 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
ENSRBIP00000030120Uncharacterized protein. (294 aa)
GNAI2G protein subunit alpha i2. (355 aa)
PDE1APhosphodiesterase. (501 aa)
ENSRBIP00000029999Protein kinase domain-containing protein. (335 aa)
ENSRBIP00000029215Uncharacterized protein. (283 aa)
PPP1R1BProtein phosphatase 1 regulatory inhibitor subunit 1B. (204 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
CNBD2Cyclic nucleotide binding domain containing 2. (610 aa)
GNA15G protein subunit alpha 15. (312 aa)
ENSRBIP00000025613Importin subunit alpha; Functions in nuclear protein import. (448 aa)
GRK2G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (690 aa)
PDE4APhosphodiesterase. (928 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
GNB5G protein subunit beta 5. (403 aa)
ADCY1Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1118 aa)
GNALG protein subunit alpha L. (448 aa)
GNAQG protein subunit alpha q. (359 aa)
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (452 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (101 aa)
PLCB2Phosphoinositide phospholipase C. (991 aa)
CAMK2GCalcium/calmodulin dependent protein kinase II gamma. (547 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1199 aa)
PDE4BPhosphodiesterase. (736 aa)
GNG10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (62 aa)
NBEAUncharacterized protein. (739 aa)
GNAI3G protein subunit alpha i3. (354 aa)
PDE4DPhosphodiesterase. (809 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (329 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
LRBAUncharacterized protein. (2348 aa)
CAMKK2Calcium/calmodulin dependent protein kinase kinase 2. (588 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
ADCY2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1091 aa)
LOC108520721Protein kinase domain-containing protein. (273 aa)
CAMK2ACalcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (489 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1210 aa)
PRKAR2BProtein kinase cAMP-dependent type II regulatory subunit beta. (412 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ADCY4Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1077 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2637 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (102 aa)
CAMK4Calcium/calmodulin dependent protein kinase IV; Belongs to the protein kinase superfamily. (472 aa)
ADCY3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1158 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1353 aa)
ENSRBIP00000020927Uncharacterized protein. (147 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
THAP7THAP domain containing 7. (309 aa)
LOC108522831PH_14 domain-containing protein. (199 aa)
PDYNProdynorphin. (254 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
THAP1THAP domain containing 1. (167 aa)
ENSRBIP00000019086Uncharacterized protein. (133 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
GNB3G protein subunit beta 3. (340 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
GNB2G protein subunit beta 2. (368 aa)
PPP2CBSerine/threonine-protein phosphatase. (304 aa)
PTRHD1Peptidyl-tRNA hydrolase domain containing 1. (140 aa)
ADCY7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1080 aa)
KPNA2IBB domain-containing protein. (70 aa)
PLA2G4APhospholipase A2. (738 aa)
GNAI1G protein subunit alpha i1. (331 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (235 aa)
PRKXProtein kinase X-linked. (261 aa)
ENSRBIP00000013012Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
ENSRBIP00000011770Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (66 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
PPP3CCSerine/threonine-protein phosphatase. (520 aa)
PDE1CPhosphodiesterase. (768 aa)
GNG13G protein subunit gamma 13. (67 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
LOC108534220Phosphodiesterase. (693 aa)
ENSRBIP00000009458Uncharacterized protein. (297 aa)
GNA14G protein subunit alpha 14. (355 aa)
CAMK2DProtein kinase domain-containing protein. (533 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
ENSRBIP00000007423Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1079 aa)
DCLK1Doublecortin like kinase 1. (740 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
GNB4G protein subunit beta 4. (340 aa)
ENSRBIP00000006659Protein kinase domain-containing protein. (275 aa)
ADCY6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1169 aa)
GNA11G protein subunit alpha 11. (354 aa)
PPP3CA-2Uncharacterized protein. (70 aa)
PRKAR2AProtein kinase cAMP-dependent type II regulatory subunit alpha. (376 aa)
POMCProopiomelanocortin. (251 aa)
ENSRBIP00000002474Uncharacterized protein. (339 aa)
PPP3CBSerine/threonine-protein phosphatase. (524 aa)
PPP3CASerine/threonine-protein phosphatase. (310 aa)
ENSRBIP00000001234Uncharacterized protein. (93 aa)
PRKCGProtein kinase C. (726 aa)
PPP3R1Uncharacterized protein. (189 aa)
PDE1BPhosphodiesterase. (536 aa)
PRKAR1AProtein kinase cAMP-dependent type I regulatory subunit alpha. (381 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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