STRINGSTRING
LMF2 LMF2 APOA2 APOA2 MTTP MTTP AP2B1 AP2B1 APOA5 APOA5 SAR1A SAR1A LDLRAP1 LDLRAP1 SOAT1 SOAT1 APOF APOF NPC2 NPC2 PCSK9 PCSK9 PRKACA PRKACA LIPG LIPG ENSRBIP00000012572 ENSRBIP00000012572 ENSRBIP00000012514 ENSRBIP00000012514 PTCHD4 PTCHD4 CDCP2 CDCP2 APOB APOB AP2A2 AP2A2 LSR LSR PLEKHD1 PLEKHD1 UBA52 UBA52 ANGPTL8 ANGPTL8 A2ML1 A2ML1 APOA4 APOA4 PTCHD3 PTCHD3 ABCG1 ABCG1 BMP1 BMP1 NPC1 NPC1 PLTP PLTP CLHC1 CLHC1 CLTA CLTA AP2M1 AP2M1 ENSRBIP00000001317 ENSRBIP00000001317 APOC3 APOC3 ENSRBIP00000003802 ENSRBIP00000003802 RPS27A RPS27A NR1H3 NR1H3 ENSRBIP00000004187 ENSRBIP00000004187 ENSRBIP00000004747 ENSRBIP00000004747 LOC108540530 LOC108540530 LOC108529634 LOC108529634 MBTPS1 MBTPS1 APOBR APOBR A2M A2M LIPC LIPC APOA1 APOA1 CREB3L3 CREB3L3 CLTC CLTC PLG PLG ILDR2 ILDR2 MBTPS2 MBTPS2 VLDLR VLDLR SOAT2 SOAT2 AP2S1 AP2S1 AADACL3 AADACL3 ZDHHC8 ZDHHC8 SCARB1 SCARB1 ANGPTL4 ANGPTL4 ALB ALB LCAT LCAT ENSRBIP00000035527 ENSRBIP00000035527 HDLBP HDLBP ENSRBIP00000035163 ENSRBIP00000035163 PRKACB PRKACB AADACL4 AADACL4 APOC4 APOC4 PTCHD1 PTCHD1 PCSK5 PCSK5 CUBN CUBN NCEH1 NCEH1 ENSRBIP00000029173 ENSRBIP00000029173 PCSK6 PCSK6 MYLIP MYLIP SMPDL3A SMPDL3A LMF1 LMF1 P4HB P4HB SAR1B SAR1B LOC108524569 LOC108524569 AMN AMN LIPA LIPA LPL LPL PCSK4 PCSK4 ENSRBIP00000023977 ENSRBIP00000023977 ABCA1 ABCA1 FURIN FURIN NR1H2 NR1H2 APOC2 APOC2 APOE APOE GPIHBP1 GPIHBP1 PZP PZP LOC108543697 LOC108543697 ENSRBIP00000020228 ENSRBIP00000020228 LOC108522909 LOC108522909 ANGPTL3 ANGPTL3 CIDEC CIDEC LDLR LDLR CETP CETP PDIA2 PDIA2 AP2A1 AP2A1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LMF2Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (707 aa)
APOA2Apolipoprotein A2. (132 aa)
MTTPMicrosomal triglyceride transfer protein. (894 aa)
AP2B1AP complex subunit beta. (951 aa)
APOA5Apolipoprotein A5. (366 aa)
SAR1AUncharacterized protein; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (278 aa)
SOAT1O-acyltransferase. (550 aa)
APOFApolipoprotein F. (326 aa)
NPC2NPC intracellular cholesterol transporter 2. (202 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (692 aa)
PRKACAProtein kinase cAMP-activated catalytic subunit alpha. (235 aa)
LIPGLipase G, endothelial type. (500 aa)
ENSRBIP00000012572Uncharacterized protein. (100 aa)
ENSRBIP00000012514Ubiquitin-like domain-containing protein. (121 aa)
PTCHD4Patched domain containing 4. (846 aa)
CDCP2CUB domain containing protein 2. (540 aa)
APOBApolipoprotein B. (4513 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (894 aa)
LSRLipolysis stimulated lipoprotein receptor. (647 aa)
PLEKHD1Pleckstrin homology and coiled-coil domain containing D1. (506 aa)
UBA52Ubiquitin-like domain-containing protein. (232 aa)
ANGPTL8Angiopoietin like 8. (198 aa)
A2ML1Alpha-2-macroglobulin like 1. (1374 aa)
APOA4Apolipoprotein A4. (420 aa)
PTCHD3Patched domain containing 3. (759 aa)
ABCG1ATP binding cassette subfamily G member 1. (676 aa)
BMP1Metalloendopeptidase. (986 aa)
NPC1NPC intracellular cholesterol transporter 1. (1277 aa)
PLTPPhospholipid transfer protein. (493 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (464 aa)
CLTAClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (248 aa)
AP2M1AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (458 aa)
ENSRBIP00000001317Ubiquitin-like domain-containing protein. (155 aa)
APOC3Apolipoprotein C3. (99 aa)
ENSRBIP00000003802Ubiquitin-like domain-containing protein. (84 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
NR1H3Nuclear receptor subfamily 1 group H member 3. (441 aa)
ENSRBIP00000004187Ubiquitin-like domain-containing protein. (153 aa)
ENSRBIP00000004747Ubiquitin-like domain-containing protein. (128 aa)
LOC108540530Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
LOC108529634Ubiquitin-like domain-containing protein. (128 aa)
MBTPS1Membrane bound transcription factor peptidase, site 1. (1052 aa)
APOBRApolipoprotein B receptor. (1128 aa)
A2MAlpha-2-macroglobulin. (1474 aa)
LIPCLipase C, hepatic type. (499 aa)
APOA1Apolipoprotein A1. (267 aa)
CREB3L3cAMP responsive element binding protein 3 like 3. (483 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1681 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (810 aa)
ILDR2Immunoglobulin like domain containing receptor 2. (639 aa)
MBTPS2Membrane bound transcription factor peptidase, site 2. (442 aa)
VLDLRVery low density lipoprotein receptor. (997 aa)
SOAT2O-acyltransferase. (526 aa)
AP2S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
AADACL3Arylacetamide deacetylase like 3. (407 aa)
ZDHHC8Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (777 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (553 aa)
ANGPTL4Angiopoietin like 4. (368 aa)
ALBAlbumin. (577 aa)
LCATLecithin-cholesterol acyltransferase. (425 aa)
ENSRBIP00000035527Uncharacterized protein. (3218 aa)
HDLBPHigh density lipoprotein binding protein. (1268 aa)
ENSRBIP00000035163B2-adapt-app_C domain-containing protein. (224 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
AADACL4Uncharacterized protein. (407 aa)
APOC4Uncharacterized protein. (127 aa)
PTCHD1Patched domain containing 1. (869 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1860 aa)
CUBNCubilin. (3431 aa)
NCEH1Neutral cholesterol ester hydrolase 1. (448 aa)
ENSRBIP00000029173Ubiquitin-like domain-containing protein. (166 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (921 aa)
MYLIPMyosin regulatory light chain interacting protein. (445 aa)
SMPDL3AAcid sphingomyelinase-like phosphodiesterase. (453 aa)
LMF1Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (506 aa)
P4HBProtein disulfide-isomerase. (517 aa)
SAR1BSecretion associated Ras related GTPase 1B; Belongs to the small GTPase superfamily. SAR1 family. (198 aa)
LOC108524569Ubiquitin-like domain-containing protein. (141 aa)
AMNAmnion associated transmembrane protein. (453 aa)
LIPALipase; Belongs to the AB hydrolase superfamily. Lipase family. (399 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (529 aa)
PCSK4Proprotein convertase subtilisin/kexin type 4; Belongs to the peptidase S8 family. (724 aa)
ENSRBIP00000023977Uncharacterized protein. (166 aa)
ABCA1ATP binding cassette subfamily A member 1. (2261 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (787 aa)
NR1H2Nuclear receptor subfamily 1 group H member 2. (461 aa)
APOC2Apolipoprotein C2. (101 aa)
APOEApolipoprotein E. (317 aa)
GPIHBP1Uncharacterized protein. (152 aa)
PZPPZP alpha-2-macroglobulin like. (1330 aa)
LOC108543697Uncharacterized protein. (1217 aa)
ENSRBIP00000020228Uncharacterized protein. (132 aa)
LOC108522909Uncharacterized protein. (384 aa)
ANGPTL3Angiopoietin like 3. (446 aa)
CIDECCell death inducing DFFA like effector c. (248 aa)
LDLRLow density lipoprotein receptor. (819 aa)
CETPCholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (493 aa)
PDIA2Protein disulfide isomerase family A member 2. (524 aa)
AP2A1AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (977 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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