STRINGSTRING
LOC108544295 LOC108544295 RIPK2 RIPK2 RPS6KA2 RPS6KA2 ENSRBIP00000004187 ENSRBIP00000004187 ENSRBIP00000004747 ENSRBIP00000004747 UBE2NL UBE2NL LOC108518098 LOC108518098 MAP3K7 MAP3K7 LOC108540530 LOC108540530 LOC108529634 LOC108529634 TAB1 TAB1 HMGB1-2 HMGB1-2 LOC108520651 LOC108520651 TLR4 TLR4 ELK1 ELK1 IRAK3 IRAK3 KHNYN KHNYN PPP2R5D PPP2R5D ENSRBIP00000006958 ENSRBIP00000006958 MAPK9 MAPK9 S100A8 S100A8 NKIRAS1 NKIRAS1 LOC108526191 LOC108526191 PPP2R1B PPP2R1B UBA52 UBA52 VRK3 VRK3 NFKB2 NFKB2 S100A9 S100A9 RPS6KA1 RPS6KA1 LRRC14 LRRC14 CD36 CD36 PPP2R1A PPP2R1A LRRC34 LRRC34 ENSRBIP00000010265 ENSRBIP00000010265 MYD88 MYD88 NLRP9 NLRP9 MEF2A MEF2A NLRP13 NLRP13 S100B S100B MAPKAPK3 MAPKAPK3 NFKB1 NFKB1 PELI3 PELI3 TAB2 TAB2 ENSRBIP00000012514 ENSRBIP00000012514 CUL1 CUL1 SIGIRR SIGIRR ATF1 ATF1 LRRC74A LRRC74A S100A12 S100A12 LRRC31 LRRC31 RPS6KA3 RPS6KA3 ENSRBIP00000014363 ENSRBIP00000014363 ENSRBIP00000014751 ENSRBIP00000014751 MAP2K1 MAP2K1 HMGB1 HMGB1 IKBKG IKBKG ENSRBIP00000015185 ENSRBIP00000015185 DUSP3 DUSP3 ENSRBIP00000016494 ENSRBIP00000016494 PPP2CB PPP2CB ATF7 ATF7 ENSRBIP00000017090 ENSRBIP00000017090 ENSRBIP00000033406 ENSRBIP00000033406 LOC108518097 LOC108518097 NOD1 NOD1 DUSP4 DUSP4 ENSRBIP00000032381 ENSRBIP00000032381 MAPK8 MAPK8 CREB5 CREB5 TRAF2 TRAF2 USP14 USP14 PPP2CA PPP2CA CASP8 CASP8 BTK BTK FGA FGA LRRC45 LRRC45 LOC108528435 LOC108528435 ENSRBIP00000039839 ENSRBIP00000039839 FNBP4 FNBP4 CREM CREM NFKBIA NFKBIA IRAK4 IRAK4 MAPK7 MAPK7 ENSRBIP00000038500 ENSRBIP00000038500 APP APP PPP4R4 PPP4R4 TAB3 TAB3 PELI2 PELI2 PPP4R1 PPP4R1 RPS6KA5 RPS6KA5 LOC108524385 LOC108524385 MAP2K7 MAP2K7 SKP1 SKP1 TRAF6 TRAF6 SFTPD SFTPD ATF2 ATF2 ECSIT ECSIT ENSRBIP00000035735 ENSRBIP00000035735 LOC108528453 LOC108528453 DUSP6 DUSP6 NLRC5 NLRC5 NKIRAS2 NKIRAS2 FGG FGG MAPK11 MAPK11 MAPKAPK2 MAPKAPK2 ENSRBIP00000033992 ENSRBIP00000033992 CREB1 CREB1 VWC2 VWC2 LOC108525504 LOC108525504 CCDC71L CCDC71L MEF2C MEF2C MAP2K4 MAP2K4 FBXW11 FBXW11 IRAK2 IRAK2 ENSRBIP00000029173 ENSRBIP00000029173 MAP3K8 MAP3K8 TP53 TP53 MAPK14 MAPK14 IKBKB IKBKB FOSL2 FOSL2 ENSRBIP00000026978 ENSRBIP00000026978 NLRX1 NLRX1 MAPK1 MAPK1 IRAK1 IRAK1 LOC108524569 LOC108524569 FOS FOS LOC108515310 LOC108515310 CHUK CHUK PELI1 PELI1 AGER AGER ENSRBIP00000023060 ENSRBIP00000023060 ALPK1 ALPK1 CD14 CD14 ENSRBIP00000022247 ENSRBIP00000022247 TLR1 TLR1 FGB FGB N4BP1 N4BP1 RELCH RELCH ENSRBIP00000020927 ENSRBIP00000020927 MAP2K6 MAP2K6 LRRC71 LRRC71 ENSRBIP00000020228 ENSRBIP00000020228 ENSRBIP00000020047 ENSRBIP00000020047 NFKBIB NFKBIB ENSRBIP00000019157 ENSRBIP00000019157 TIRAP TIRAP MAPK15 MAPK15 NLRP6 NLRP6 RELA RELA MAP3K20 MAP3K20 MAP2K3 MAP2K3 BTRC BTRC TLR2 TLR2 MAPK3 MAPK3 RPS27A RPS27A MAP3K1 MAP3K1 LY96 LY96 TNIP2 TNIP2 SOCS1 SOCS1 ENSRBIP00000001317 ENSRBIP00000001317 TIFA TIFA DUSP7 DUSP7 ENSRBIP00000002911 ENSRBIP00000002911 NOD2 NOD2 MAPK10 MAPK10 TONSL TONSL ENSRBIP00000003802 ENSRBIP00000003802
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC108544295Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (443 aa)
RPS6KA2Ribosomal protein S6 kinase. (758 aa)
ENSRBIP00000004187Ubiquitin-like domain-containing protein. (153 aa)
ENSRBIP00000004747Ubiquitin-like domain-containing protein. (128 aa)
UBE2NLUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (89 aa)
LOC108518098C-type lectin domain-containing protein. (248 aa)
MAP3K7Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa)
LOC108540530Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
LOC108529634Ubiquitin-like domain-containing protein. (128 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (512 aa)
HMGB1-2Uncharacterized protein. (215 aa)
LOC108520651UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
TLR4Toll like receptor 4; Belongs to the Toll-like receptor family. (843 aa)
ELK1ETS domain-containing protein. (428 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (596 aa)
KHNYNKH and NYN domain containing. (678 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (605 aa)
ENSRBIP00000006958TNF receptor-associated factor. (473 aa)
MAPK9Mitogen-activated protein kinase. (407 aa)
S100A8EF-hand domain-containing protein; Belongs to the S-100 family. (171 aa)
NKIRAS1NFKB inhibitor interacting Ras like 1. (192 aa)
LOC108526191UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (112 aa)
PPP2R1BProtein phosphatase 2 scaffold subunit Abeta. (667 aa)
UBA52Ubiquitin-like domain-containing protein. (232 aa)
VRK3VRK serine/threonine kinase 3. (479 aa)
NFKB2Nuclear factor kappa B subunit 2. (906 aa)
S100A9Protein S100; Belongs to the S-100 family. (114 aa)
RPS6KA1Ribosomal protein S6 kinase. (744 aa)
LRRC14Leucine rich repeat containing 14. (493 aa)
CD36CD36 molecule; Belongs to the CD36 family. (472 aa)
PPP2R1AProtein phosphatase 2 scaffold subunit Aalpha. (589 aa)
LRRC34Leucine rich repeat containing 34. (457 aa)
ENSRBIP00000010265Uncharacterized protein. (161 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (309 aa)
NLRP9NLR family pyrin domain containing 9. (933 aa)
MEF2AMyocyte enhancer factor 2A. (511 aa)
NLRP13NLR family pyrin domain containing 13. (1044 aa)
S100BS_100 domain-containing protein; Belongs to the S-100 family. (94 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (434 aa)
NFKB1Nuclear factor kappa B subunit 1. (969 aa)
PELI3Pellino E3 ubiquitin protein ligase family member 3. (397 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa)
ENSRBIP00000012514Ubiquitin-like domain-containing protein. (121 aa)
CUL1Cullin 1; Belongs to the cullin family. (776 aa)
SIGIRRSingle Ig and TIR domain containing. (502 aa)
ATF1Activating transcription factor 1. (269 aa)
LRRC74ALeucine rich repeat containing 74A. (485 aa)
S100A12S100 calcium binding protein A12; Belongs to the S-100 family. (90 aa)
LRRC31Leucine rich repeat containing 31. (552 aa)
RPS6KA3Uncharacterized protein. (66 aa)
ENSRBIP00000014363UBIQUITIN_CONJUGAT_2 domain-containing protein. (128 aa)
ENSRBIP00000014751UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (105 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (393 aa)
HMGB1Uncharacterized protein. (181 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (347 aa)
ENSRBIP00000015185ETS domain-containing protein. (421 aa)
DUSP3Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (185 aa)
ENSRBIP00000016494Protein kinase domain-containing protein. (253 aa)
PPP2CBSerine/threonine-protein phosphatase. (304 aa)
ATF7Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (494 aa)
ENSRBIP00000017090Uncharacterized protein. (120 aa)
ENSRBIP00000033406UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (142 aa)
LOC108518097C-type lectin domain-containing protein. (336 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
ENSRBIP00000032381Uncharacterized protein. (130 aa)
MAPK8Mitogen-activated protein kinase 8. (383 aa)
CREB5Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription. (503 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
USP14Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (493 aa)
PPP2CASerine/threonine-protein phosphatase. (309 aa)
CASP8Caspase 8; Belongs to the peptidase C14A family. (542 aa)
BTKTyrosine-protein kinase. (673 aa)
FGAFibrinogen alpha chain. (906 aa)
LRRC45Leucine rich repeat containing 45. (669 aa)
LOC108528435Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (130 aa)
ENSRBIP00000039839Uncharacterized protein; Belongs to the SKP1 family. (129 aa)
FNBP4Formin binding protein 4. (925 aa)
CREMcAMP responsive element modulator. (330 aa)
NFKBIANFKB inhibitor alpha. (317 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (461 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (814 aa)
ENSRBIP00000038500RHD domain-containing protein. (112 aa)
APPAmyloid beta precursor protein. (770 aa)
PPP4R4Protein phosphatase 4 regulatory subunit 4. (807 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (690 aa)
PELI2E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (420 aa)
PPP4R1Protein phosphatase 4 regulatory subunit 1. (930 aa)
RPS6KA5Non-specific serine/threonine protein kinase. (684 aa)
LOC108524385Uncharacterized protein. (348 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (414 aa)
SKP1Uncharacterized protein; Belongs to the SKP1 family. (154 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (522 aa)
SFTPDSurfactant protein D. (414 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (429 aa)
ECSITECSIT signalling integrator. (432 aa)
ENSRBIP00000035735Uncharacterized protein. (100 aa)
LOC108528453Serum amyloid A protein; Major acute phase reactant. Apolipoprotein of the HDL complex. (122 aa)
DUSP6Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (381 aa)
NLRC5NLR family CARD domain containing 5. (1866 aa)
NKIRAS2NFKB inhibitor interacting Ras like 2. (231 aa)
FGGFibrinogen gamma chain. (453 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
MAPKAPK2MAPK activated protein kinase 2. (392 aa)
ENSRBIP00000033992Uncharacterized protein. (157 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
LOC108525504Uncharacterized protein. (70 aa)
CCDC71LCoiled-coil domain containing 71 like. (235 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
MAP2K4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (408 aa)
FBXW11F-box and WD repeat domain containing 11. (522 aa)
IRAK2Interleukin 1 receptor associated kinase 2. (537 aa)
ENSRBIP00000029173Ubiquitin-like domain-containing protein. (166 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (466 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (789 aa)
FOSL2FOS like 2, AP-1 transcription factor subunit. (326 aa)
ENSRBIP00000026978Uncharacterized protein. (179 aa)
NLRX1NLR family member X1. (972 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
IRAK1Interleukin 1 receptor associated kinase 1. (702 aa)
LOC108524569Ubiquitin-like domain-containing protein. (141 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
LOC108515310WRNPLPNID domain-containing protein. (954 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
PELI1E3 ubiquitin-protein ligase pellino homolog; E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. (418 aa)
AGERUncharacterized protein. (417 aa)
ENSRBIP00000023060Protein kinase domain-containing protein. (120 aa)
ALPK1Alpha kinase 1. (1245 aa)
CD14CD14 molecule. (384 aa)
ENSRBIP00000022247Uncharacterized protein. (70 aa)
TLR1Toll like receptor 1. (703 aa)
FGBFibrinogen beta chain. (491 aa)
N4BP1NEDD4 binding protein 1. (895 aa)
RELCHRAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1216 aa)
ENSRBIP00000020927Uncharacterized protein. (147 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa)
LRRC71Leucine rich repeat containing 71. (559 aa)
ENSRBIP00000020228Uncharacterized protein. (132 aa)
ENSRBIP00000020047Uncharacterized protein; Belongs to the SKP1 family. (162 aa)
NFKBIBNFKB inhibitor beta. (338 aa)
ENSRBIP00000019157UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (78 aa)
TIRAPTIR domain containing adaptor protein. (233 aa)
MAPK15Mitogen-activated protein kinase. (544 aa)
NLRP6NLR family pyrin domain containing 6. (1041 aa)
RELAUncharacterized protein. (282 aa)
MAP3K20Mitogen-activated protein kinase kinase kinase 20. (800 aa)
MAP2K3Mitogen-activated protein kinase kinase 3; Belongs to the protein kinase superfamily. (394 aa)
BTRCBeta-transducin repeat containing E3 ubiquitin protein ligase. (605 aa)
TLR2Toll-like receptor. (784 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
MAP3K1Mitogen-activated protein kinase kinase kinase 1. (1374 aa)
LY96Lymphocyte antigen 96. (160 aa)
TNIP2CCHC NOA-type domain-containing protein. (337 aa)
SOCS1Suppressor of cytokine signaling 1. (215 aa)
ENSRBIP00000001317Ubiquitin-like domain-containing protein. (155 aa)
TIFATRAF interacting protein with forkhead associated domain. (185 aa)
DUSP7Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (419 aa)
ENSRBIP00000002911Uncharacterized protein. (190 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1153 aa)
MAPK10Mitogen-activated protein kinase. (528 aa)
TONSLTonsoku like, DNA repair protein. (1367 aa)
ENSRBIP00000003802Ubiquitin-like domain-containing protein. (84 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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