STRINGSTRING
EPGN EPGN SPRY1 SPRY1 ENSRBIP00000000419 ENSRBIP00000000419 EPN1 EPN1 RPS27A RPS27A ENSRBIP00000001317 ENSRBIP00000001317 ENSRBIP00000003802 ENSRBIP00000003802 ENSRBIP00000004187 ENSRBIP00000004187 ENSRBIP00000004747 ENSRBIP00000004747 LOC108540530 LOC108540530 LOC108529634 LOC108529634 HGS HGS SH3GL2 SH3GL2 EREG EREG UBA52 UBA52 PTPRT PTPRT STAM STAM ENSRBIP00000012514 ENSRBIP00000012514 SH3GL3 SH3GL3 TGFA TGFA STAM2 STAM2 ENSRBIP00000015347 ENSRBIP00000015347 ENSRBIP00000016224 ENSRBIP00000016224 EGF EGF GRB2 GRB2 PTPN12 PTPN12 SH3KBP1 SH3KBP1 ENSRBIP00000020228 ENSRBIP00000020228 SH3GL1 SH3GL1 ARHGEF7 ARHGEF7 LOC108524569 LOC108524569 ENSRBIP00000026615 ENSRBIP00000026615 BTC BTC PTPRM PTPRM ENSRBIP00000029173 ENSRBIP00000029173 HBEGF HBEGF PTPRT-2 PTPRT-2 PTPN3 PTPN3 AREG AREG EGFR EGFR CDC42 CDC42 ENSRBIP00000037737 ENSRBIP00000037737 CBL CBL ENSRBIP00000038277 ENSRBIP00000038277 EPS15 EPS15 EPS15L1 EPS15L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPGNEpithelial mitogen. (156 aa)
SPRY1Sprouty RTK signaling antagonist 1. (319 aa)
ENSRBIP00000000419Uncharacterized protein. (191 aa)
EPN1Epsin 1. (662 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSRBIP00000001317Ubiquitin-like domain-containing protein. (155 aa)
ENSRBIP00000003802Ubiquitin-like domain-containing protein. (84 aa)
ENSRBIP00000004187Ubiquitin-like domain-containing protein. (153 aa)
ENSRBIP00000004747Ubiquitin-like domain-containing protein. (128 aa)
LOC108540530Ubiquitin A-52 residue ribosomal protein fusion product 1. (77 aa)
LOC108529634Ubiquitin-like domain-containing protein. (128 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
SH3GL2SH3 domain containing GRB2 like 2, endophilin A1. (315 aa)
EREGEpiregulin. (169 aa)
UBA52Ubiquitin-like domain-containing protein. (232 aa)
PTPRTProtein tyrosine phosphatase receptor type T. (1059 aa)
STAMSignal transducing adaptor molecule. (540 aa)
ENSRBIP00000012514Ubiquitin-like domain-containing protein. (121 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (286 aa)
TGFATransforming growth factor alpha. (166 aa)
STAM2Signal transducing adaptor molecule 2. (519 aa)
ENSRBIP00000015347Uncharacterized protein. (182 aa)
ENSRBIP00000016224Uncharacterized protein. (184 aa)
EGFPro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1208 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
PTPN12Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (763 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (372 aa)
ENSRBIP00000020228Uncharacterized protein. (132 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (368 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (755 aa)
LOC108524569Ubiquitin-like domain-containing protein. (141 aa)
ENSRBIP00000026615Uncharacterized protein. (185 aa)
BTCBetacellulin. (129 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1496 aa)
ENSRBIP00000029173Ubiquitin-like domain-containing protein. (166 aa)
HBEGFHeparin binding EGF like growth factor. (208 aa)
PTPRT-2Uncharacterized protein. (339 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (913 aa)
AREGAmphiregulin. (264 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
CDC42Uncharacterized protein. (191 aa)
ENSRBIP00000037737annotation not available (191 aa)
CBLCbl proto-oncogene. (802 aa)
ENSRBIP00000038277Uncharacterized protein. (843 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (899 aa)
EPS15L1Uncharacterized protein. (899 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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