STRINGSTRING
SHD SHD VEGFC VEGFC NCF1 NCF1 RNF222 RNF222 ENSRBIP00000000419 ENSRBIP00000000419 LPXN LPXN HSH2D HSH2D CRK CRK VAV2 VAV2 PIK3R1 PIK3R1 ELMO1 ELMO1 SRC SRC KDR KDR ENSRBIP00000002732 ENSRBIP00000002732 ENSRBIP00000002994 ENSRBIP00000002994 ACTB ACTB MLST8 MLST8 TENM2 TENM2 SHB SHB MTOR MTOR BRK1 BRK1 ABI1 ABI1 ACTRT1 ACTRT1 FYN FYN ERAS ERAS MAPK12 MAPK12 NCF2 NCF2 ITGB3 ITGB3 ENSRBIP00000009160 ENSRBIP00000009160 VEGFD VEGFD SHC2 SHC2 ROCK1 ROCK1 PTK2 PTK2 CYFIP1 CYFIP1 ACTL7B ACTL7B AKT1 AKT1 FNDC3B FNDC3B CYBA CYBA STX7 STX7 ABI2 ABI2 MAPKAPK3 MAPKAPK3 HSPB1 HSPB1 PIK3CB PIK3CB NCK1 NCK1 PTK2B PTK2B ENSRBIP00000013453 ENSRBIP00000013453 BCAR1 BCAR1 PIK3R2 PIK3R2 PDPK1 PDPK1 NEDD9 NEDD9 ENSRBIP00000015006 ENSRBIP00000015006 AXL AXL PGF PGF ENSRBIP00000015347 ENSRBIP00000015347 CAV1 CAV1 PXN PXN THEM4 THEM4 CASS4 CASS4 ENSRBIP00000016224 ENSRBIP00000016224 AHCYL1 AHCYL1 TGFB1I1 TGFB1I1 NCKAP1L NCKAP1L ACTL8 ACTL8 ITGAV ITGAV PIK3CA PIK3CA SHE SHE SZRD1 SZRD1 LOC108522676 LOC108522676 ELMO3 ELMO3 JUP JUP WASF3 WASF3 FNDC3A FNDC3A PRKCA PRKCA LOC108537061 LOC108537061 PAK1 PAK1 PAK2 PAK2 TENM4 TENM4 HRAS HRAS PRKCB PRKCB VEGFB VEGFB NRP1 NRP1 ENSRBIP00000022666 ENSRBIP00000022666 ENSRBIP00000022670 ENSRBIP00000022670 CTNNB1 CTNNB1 ITPR2 ITPR2 PRKCD PRKCD NRP2 NRP2 ITPR1 ITPR1 BAIAP2 BAIAP2 ENSRBIP00000024768 ENSRBIP00000024768 STX12 STX12 SPHK1 SPHK1 CYBB CYBB FLT1 FLT1 RASA1 RASA1 TENM3 TENM3 KRAS KRAS ENSRBIP00000026615 ENSRBIP00000026615 EFS EFS ACTL7A ACTL7A MAPK14 MAPK14 ARVCF ARVCF CSDE1-2 CSDE1-2 ENSRBIP00000028717 ENSRBIP00000028717 ENSRBIP00000029649 ENSRBIP00000029649 CSDE1 CSDE1 ENSRBIP00000030972 ENSRBIP00000030972 RICTOR RICTOR ENSRBIP00000031488 ENSRBIP00000031488 TRIB3 TRIB3 ACTG1 ACTG1 MAPK13 MAPK13 HSP90AA1 HSP90AA1 WASF1 WASF1 AKT2 AKT2 ENSRBIP00000034107 ENSRBIP00000034107 NOS3 NOS3 AKT3 AKT3 MAPKAPK2 MAPKAPK2 CDH5 CDH5 MAPK11 MAPK11 VAV1 VAV1 NCK2 NCK2 TENM1 TENM1 NCKAP1 NCKAP1 PRKACB PRKACB ENSRBIP00000035173 ENSRBIP00000035173 ENSRBIP00000035213 ENSRBIP00000035213 VEGFA VEGFA FLT4 FLT4 VAV3 VAV3 SH2D2A SH2D2A SHF SHF AAMP AAMP WASF2 WASF2 PRKCZ PRKCZ ELMO2 ELMO2 PRR5 PRR5 CDC42 CDC42 CYFIP2 CYFIP2 ENSRBIP00000037737 ENSRBIP00000037737 PLCG1 PLCG1 NRAS NRAS DOCK1 DOCK1 NCF4 NCF4 ENSRBIP00000040717 ENSRBIP00000040717 CTNNA1 CTNNA1 CTNND1 CTNND1 MAPKAP1 MAPKAP1 ITPR3 ITPR3 ROCK2 ROCK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHDSrc homology 2 domain containing transforming protein D. (241 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (350 aa)
NCF1Neutrophil cytosolic factor 1. (372 aa)
RNF222Ring finger protein 222. (220 aa)
ENSRBIP00000000419Uncharacterized protein. (191 aa)
LPXNLeupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa)
HSH2DHematopoietic SH2 domain containing. (327 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
VAV2Vav guanine nucleotide exchange factor 2. (783 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ELMO1Engulfment and cell motility 1. (692 aa)
SRCTyrosine-protein kinase. (627 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
ENSRBIP00000002732SUZ domain-containing protein. (127 aa)
ENSRBIP00000002994Protein kinase domain-containing protein. (358 aa)
ACTBActin beta. (379 aa)
MLST8MTOR associated protein, LST8 homolog. (335 aa)
TENM2Teneurin transmembrane protein 2. (2602 aa)
SHBSH2 domain containing adaptor protein B. (509 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2527 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
ABI1Abl interactor 1. (508 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
FYNTyrosine-protein kinase. (537 aa)
ERASES cell expressed Ras. (233 aa)
MAPK12Mitogen-activated protein kinase. (369 aa)
NCF2Neutrophil cytosolic factor 2. (526 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (788 aa)
ENSRBIP00000009160SUZ domain-containing protein. (141 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (354 aa)
SHC2Uncharacterized protein. (421 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1341 aa)
PTK2Protein tyrosine kinase 2. (1078 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
ACTL7BActin like 7B; Belongs to the actin family. (399 aa)
AKT1AKT serine/threonine kinase 1. (486 aa)
FNDC3BFibronectin type III domain containing 3B. (1178 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (194 aa)
STX7Syntaxin 7; Belongs to the syntaxin family. (261 aa)
ABI2Abl interactor 2. (463 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (434 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (205 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (929 aa)
NCK1NCK adaptor protein 1. (371 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1009 aa)
ENSRBIP00000013453SHSP domain-containing protein; Belongs to the small heat shock protein (HSP20) family. (173 aa)
BCAR1BCAR1 scaffold protein, Cas family member. (906 aa)
PIK3R2Uncharacterized protein. (626 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (351 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (839 aa)
ENSRBIP00000015006Uncharacterized protein. (131 aa)
AXLAXL receptor tyrosine kinase. (892 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
ENSRBIP00000015347Uncharacterized protein. (182 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (147 aa)
PXNPaxillin. (1083 aa)
THEM4Thioesterase superfamily member 4. (207 aa)
CASS4Cas scaffold protein family member 4. (786 aa)
ENSRBIP00000016224Uncharacterized protein. (184 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (444 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
SHESrc homology 2 domain containing E. (495 aa)
SZRD1SUZ RNA binding domain containing 1. (152 aa)
LOC108522676Protein kinase domain-containing protein. (299 aa)
ELMO3Engulfment and cell motility 3. (768 aa)
JUPJunction plakoglobin. (709 aa)
WASF3WASP family member 3. (502 aa)
FNDC3AFibronectin type III domain containing 3A. (1198 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (604 aa)
LOC108537061HATPase_c domain-containing protein. (384 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
PAK2Non-specific serine/threonine protein kinase. (539 aa)
TENM4Teneurin transmembrane protein 4. (2848 aa)
HRASHRas proto-oncogene, GTPase. (189 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (630 aa)
VEGFBVascular endothelial growth factor B. (183 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
ENSRBIP00000022666Uncharacterized protein. (379 aa)
ENSRBIP00000022670Uncharacterized protein. (281 aa)
CTNNB1Catenin beta 1. (781 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2637 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (930 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
BAIAP2BAI1 associated protein 2. (605 aa)
ENSRBIP00000024768Uncharacterized protein; Belongs to the actin family. (156 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (276 aa)
SPHK1Sphingosine kinase 1. (384 aa)
CYBBCytochrome b-245 beta chain. (513 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1337 aa)
RASA1RAS p21 protein activator 1. (1016 aa)
TENM3Teneurin transmembrane protein 3. (2609 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ENSRBIP00000026615Uncharacterized protein. (185 aa)
EFSEmbryonal Fyn-associated substrate. (559 aa)
ACTL7AActin like 7A; Belongs to the actin family. (395 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
ARVCFARVCF delta catenin family member. (935 aa)
CSDE1-2Uncharacterized protein. (820 aa)
ENSRBIP00000028717Uncharacterized protein. (173 aa)
ENSRBIP00000029649DH domain-containing protein. (251 aa)
CSDE1Uncharacterized protein. (818 aa)
ENSRBIP00000030972Teneurin N-terminal domain-containing protein. (186 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1729 aa)
ENSRBIP00000031488Uncharacterized protein. (67 aa)
TRIB3Tribbles pseudokinase 3. (385 aa)
ACTG1Actin gamma 1. (377 aa)
MAPK13Mitogen-activated protein kinase. (365 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (686 aa)
WASF1WASP family member 1. (559 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (481 aa)
ENSRBIP00000034107HATPase_c domain-containing protein. (638 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1205 aa)
AKT3AKT serine/threonine kinase 3; Belongs to the protein kinase superfamily. (389 aa)
MAPKAPK2MAPK activated protein kinase 2. (392 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (788 aa)
MAPK11Mitogen-activated protein kinase. (364 aa)
VAV1Vav guanine nucleotide exchange factor 1. (843 aa)
NCK2Cytoplasmic protein. (380 aa)
TENM1Teneurin transmembrane protein 1. (1665 aa)
NCKAP1NCK associated protein 1. (1112 aa)
PRKACBProtein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa)
ENSRBIP00000035173Uncharacterized protein. (96 aa)
ENSRBIP00000035213Uncharacterized protein; Belongs to the actin family. (362 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (409 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1329 aa)
VAV3Uncharacterized protein. (287 aa)
SH2D2ASH2 domain containing 2A. (412 aa)
SHFSrc homology 2 domain containing F. (421 aa)
AAMPAngio associated migratory cell protein. (434 aa)
WASF2WASP family member 2. (498 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (615 aa)
ELMO2Engulfment and cell motility 2. (718 aa)
PRR5Proline rich 5. (410 aa)
CDC42Uncharacterized protein. (191 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
ENSRBIP00000037737annotation not available (191 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1930 aa)
NCF4Neutrophil cytosolic factor 4. (339 aa)
ENSRBIP00000040717Uncharacterized protein. (100 aa)
CTNNA1Catenin alpha 1. (906 aa)
CTNND1Catenin delta 1. (968 aa)
MAPKAP1MAPK associated protein 1. (522 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1387 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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