STRINGSTRING
JAG2 JAG2 UBA52 UBA52 HES1 HES1 ADAM10 ADAM10 JAG1 JAG1 NCSTN NCSTN NEURL1 NEURL1 MIB2 MIB2 APH1A APH1A HES5 HES5 CNTN1 CNTN1 NEURL1B NEURL1B ENSRBIP00000029173 ENSRBIP00000029173 MAMLD1 MAMLD1 MIB1 MIB1 PSEN2 PSEN2 RBPJ RBPJ EP300 EP300 ENSRBIP00000033881 ENSRBIP00000033881 CREB1 CREB1 GZMB GZMB NOTCH2 NOTCH2 MAML1 MAML1 APH1B APH1B MDK MDK DLL4 DLL4 MAML2 MAML2 PSENEN PSENEN ENSRBIP00000021702 ENSRBIP00000021702 HES4 HES4 RPS27A RPS27A ENSRBIP00000001317 ENSRBIP00000001317 FCER2 FCER2 ENSRBIP00000003802 ENSRBIP00000003802 PSEN1 PSEN1 ENSRBIP00000004187 ENSRBIP00000004187 DLL1 DLL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1075 aa)
UBA52Ubiquitin-like domain-containing protein. (232 aa)
HES1Hes family bHLH transcription factor 1. (277 aa)
ADAM10ADAM metallopeptidase domain 10. (748 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
NCSTNNicastrin. (709 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (652 aa)
MIB2Mindbomb E3 ubiquitin protein ligase 2. (960 aa)
APH1AAph-1 homolog A, gamma-secretase subunit. (265 aa)
HES5Hes family bHLH transcription factor 5. (152 aa)
CNTN1Contactin 1. (1005 aa)
NEURL1BNeuralized E3 ubiquitin protein ligase 1B. (555 aa)
ENSRBIP00000029173Ubiquitin-like domain-containing protein. (166 aa)
MAMLD1Mastermind like domain containing 1. (1020 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1012 aa)
PSEN2Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (481 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (531 aa)
EP300E1A binding protein p300. (2296 aa)
ENSRBIP00000033881Uncharacterized protein. (61 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
GZMBGranzyme B; Belongs to the peptidase S1 family. (247 aa)
NOTCH2Notch receptor 2. (2532 aa)
MAML1Mastermind like transcriptional coactivator 1. (961 aa)
APH1BAph-1 homolog B, gamma-secretase subunit. (257 aa)
MDKUncharacterized protein. (143 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (724 aa)
MAML2Mastermind like transcriptional coactivator 2. (1147 aa)
PSENENPresenilin enhancer, gamma-secretase subunit. (101 aa)
ENSRBIP00000021702Uncharacterized protein. (144 aa)
HES4Hes family bHLH transcription factor 4. (188 aa)
RPS27AUbiquitin-like domain-containing protein. (156 aa)
ENSRBIP00000001317Ubiquitin-like domain-containing protein. (155 aa)
FCER2Fc fragment of IgE receptor II. (321 aa)
ENSRBIP00000003802Ubiquitin-like domain-containing protein. (84 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (432 aa)
ENSRBIP00000004187Ubiquitin-like domain-containing protein. (153 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (748 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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