STRINGSTRING
ACTR2 ACTR2 WAS WAS BTK BTK ITPR3 ITPR3 PLD1 PLD1 ENSRBIP00000040941 ENSRBIP00000040941 PRKCE PRKCE DOCK1 DOCK1 PLA2G6 PLA2G6 ARPC5L ARPC5L MYO1A MYO1A PLCG1 PLCG1 MYH9 MYH9 ENSRBIP00000038008 ENSRBIP00000038008 ENSRBIP00000037737 ENSRBIP00000037737 CYFIP2 CYFIP2 HSP90AB1 HSP90AB1 CDC42 CDC42 ELMO2 ELMO2 WASF2 WASF2 ENSRBIP00000036977 ENSRBIP00000036977 VAV3 VAV3 LYN LYN PLD2 PLD2 ENSRBIP00000035548 ENSRBIP00000035548 ENSRBIP00000035373 ENSRBIP00000035373 ENSRBIP00000035213 ENSRBIP00000035213 ENSRBIP00000035173 ENSRBIP00000035173 WIPF1 WIPF1 NCKAP1 NCKAP1 VAV1 VAV1 ENSRBIP00000034107 ENSRBIP00000034107 LOC108527771 LOC108527771 WASF1 WASF1 LOC108516810 LOC108516810 HSP90AA1 HSP90AA1 FMN1 FMN1 MYO1C MYO1C ACTG1 ACTG1 YES1 YES1 ENSRBIP00000032770 ENSRBIP00000032770 MYO10 MYO10 FGR FGR ENSRBIP00000031488 ENSRBIP00000031488 MYO1B MYO1B ENSRBIP00000030045 ENSRBIP00000030045 IGKV1OR2-108 IGKV1OR2-108 ENSRBIP00000029649 ENSRBIP00000029649 LOC108538696 LOC108538696 ENSRBIP00000028717 ENSRBIP00000028717 ENSRBIP00000028305 ENSRBIP00000028305 IGKV4-1 IGKV4-1 LOC108522153 LOC108522153 ENSRBIP00000028119 ENSRBIP00000028119 ENSRBIP00000027876 ENSRBIP00000027876 ACTL7A ACTL7A ENSRBIP00000027252 ENSRBIP00000027252 ENSRBIP00000027226 ENSRBIP00000027226 IGLV9-49 IGLV9-49 PLPP5 PLPP5 ENSRBIP00000026615 ENSRBIP00000026615 MAPK1 MAPK1 MYO5C MYO5C ENSRBIP00000024991 ENSRBIP00000024991 ENSRBIP00000024768 ENSRBIP00000024768 ENSRBIP00000024420 ENSRBIP00000024420 NF2 NF2 ENSRBIP00000023765 ENSRBIP00000023765 BAIAP2 BAIAP2 ITPR1 ITPR1 ARPC2 ARPC2 SYK SYK PRKCD PRKCD ITPR2 ITPR2 ENSRBIP00000022670 ENSRBIP00000022670 ENSRBIP00000022666 ENSRBIP00000022666 MYO9B MYO9B ENSRBIP00000022174 ENSRBIP00000022174 ENSRBIP00000021960 ENSRBIP00000021960 ACTR3 ACTR3 MYO1H MYO1H MYO1G MYO1G PAK1 PAK1 ENSRBIP00000020710 ENSRBIP00000020710 ENSRBIP00000020593 ENSRBIP00000020593 LOC108537061 LOC108537061 ARPC1A ARPC1A WASHC1 WASHC1 WIPF3 WIPF3 TRAV22 TRAV22 ENSRBIP00000019284 ENSRBIP00000019284 IGLV3-19 IGLV3-19 WASF3 WASF3 LOC108525261 LOC108525261 ENSRBIP00000018225 ENSRBIP00000018225 ELMO3 ELMO3 ENSRBIP00000018134 ENSRBIP00000018134 PIK3CA PIK3CA PLD5 PLD5 ENSRBIP00000017624 ENSRBIP00000017624 ACTL8 ACTL8 NCKAP1L NCKAP1L WASL WASL ENSRBIP00000016972 ENSRBIP00000016972 AHCYL1 AHCYL1 ENSRBIP00000016723 ENSRBIP00000016723 GRB2 GRB2 ENSRBIP00000016224 ENSRBIP00000016224 ENSRBIP00000015347 ENSRBIP00000015347 LOC108520315 LOC108520315 ENSRBIP00000015229 ENSRBIP00000015229 PLD3 PLD3 ENSRBIP00000015006 ENSRBIP00000015006 FMN2 FMN2 PIK3R2 PIK3R2 WIPF2 WIPF2 MYO1D MYO1D NCKIPSD NCKIPSD PLCG2 PLCG2 NCK1 NCK1 ARPC3 ARPC3 ENSRBIP00000012838 ENSRBIP00000012838 ENSRBIP00000012540 ENSRBIP00000012540 PIK3CB PIK3CB ENSRBIP00000011981 ENSRBIP00000011981 ABI2 ABI2 IGLV6-57 IGLV6-57 ACTL7B ACTL7B CYFIP1 CYFIP1 PTK2 PTK2 LIMK1 LIMK1 ARPC5 ARPC5 ENSRBIP00000009632 ENSRBIP00000009632 ENSRBIP00000009494 ENSRBIP00000009494 DSTN DSTN ACTR3B ACTR3B ENSRBIP00000009191 ENSRBIP00000009191 ENSRBIP00000008952 ENSRBIP00000008952 PLPP4 PLPP4 ENSRBIP00000008268 ENSRBIP00000008268 ABL1 ABL1 CD3G CD3G MYO5A MYO5A PLD4 PLD4 FYN FYN ENSRBIP00000005991 ENSRBIP00000005991 HSP90AB1-2 HSP90AB1-2 ACTRT1 ACTRT1 ABI1 ABI1 BRK1 BRK1 ARPC1B ARPC1B ENSRBIP00000004532 ENSRBIP00000004532 ACTB ACTB ARPC4 ARPC4 CFL1 CFL1 HCK HCK SRC SRC ELMO1 ELMO1 LOC108530360 LOC108530360 PIK3R1 PIK3R1 ENSRBIP00000001398 ENSRBIP00000001398 VAV2 VAV2 CRK CRK CFL2 CFL2 CD247 CD247 MAPK3 MAPK3 ENSRBIP00000000419 ENSRBIP00000000419 ENSRBIP00000000138 ENSRBIP00000000138
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (399 aa)
WASWASP actin nucleation promoting factor. (455 aa)
BTKTyrosine-protein kinase. (673 aa)
ITPR3Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
PLD1Phospholipase. (968 aa)
ENSRBIP00000040941Ig-like domain-containing protein. (127 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1930 aa)
PLA2G6Phospholipase A2 group VI. (806 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa)
MYO1AMyosin IA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1043 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1291 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1962 aa)
ENSRBIP00000038008HATPase_c domain-containing protein. (695 aa)
ENSRBIP00000037737annotation not available (191 aa)
CYFIP2Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa)
HSP90AB1HATPase_c domain-containing protein. (701 aa)
CDC42Uncharacterized protein. (191 aa)
ELMO2Engulfment and cell motility 2. (718 aa)
WASF2WASP family member 2. (498 aa)
ENSRBIP00000036977Protein kinase domain-containing protein. (68 aa)
VAV3Uncharacterized protein. (287 aa)
LYNTyrosine-protein kinase. (512 aa)
PLD2Phospholipase. (853 aa)
ENSRBIP00000035548Uncharacterized protein. (110 aa)
ENSRBIP00000035373Uncharacterized protein. (225 aa)
ENSRBIP00000035213Uncharacterized protein; Belongs to the actin family. (362 aa)
ENSRBIP00000035173Uncharacterized protein. (96 aa)
WIPF1WAS/WASL interacting protein family member 1. (500 aa)
NCKAP1NCK associated protein 1. (1112 aa)
VAV1Vav guanine nucleotide exchange factor 1. (843 aa)
ENSRBIP00000034107HATPase_c domain-containing protein. (638 aa)
LOC108527771Ig-like domain-containing protein. (212 aa)
WASF1WASP family member 1. (559 aa)
LOC108516810Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (330 aa)
HSP90AA1Heat shock protein 90 alpha family class A member 1. (686 aa)
FMN1Formin 1. (1256 aa)
MYO1CMyosin IC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1051 aa)
ACTG1Actin gamma 1. (377 aa)
YES1Tyrosine-protein kinase. (480 aa)
ENSRBIP00000032770Ig-like domain-containing protein. (144 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2009 aa)
FGRTyrosine-protein kinase. (529 aa)
ENSRBIP00000031488Uncharacterized protein. (67 aa)
MYO1BMyosin IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1132 aa)
ENSRBIP00000030045IGv domain-containing protein. (73 aa)
IGKV1OR2-108Immunoglobulin kappa variable 1/OR2-108 (non-functional). (141 aa)
ENSRBIP00000029649DH domain-containing protein. (251 aa)
LOC108538696Uncharacterized protein. (351 aa)
ENSRBIP00000028717Uncharacterized protein. (173 aa)
ENSRBIP00000028305Ig-like domain-containing protein. (162 aa)
IGKV4-1Immunoglobulin kappa variable 4-1. (168 aa)
LOC108522153Ig-like domain-containing protein. (198 aa)
ENSRBIP00000028119Ig-like domain-containing protein. (142 aa)
ENSRBIP00000027876Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (353 aa)
ACTL7AActin like 7A; Belongs to the actin family. (395 aa)
ENSRBIP00000027252Ig-like domain-containing protein. (149 aa)
ENSRBIP00000027226Ig-like domain-containing protein. (139 aa)
IGLV9-49Immunoglobulin lambda variable 9-49. (123 aa)
PLPP5Phospholipid phosphatase 5. (314 aa)
ENSRBIP00000026615Uncharacterized protein. (185 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (342 aa)
MYO5CMyosin VC; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1742 aa)
ENSRBIP00000024991HATPase_c domain-containing protein. (571 aa)
ENSRBIP00000024768Uncharacterized protein; Belongs to the actin family. (156 aa)
ENSRBIP00000024420Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (173 aa)
NF2Neurofibromin 2. (542 aa)
ENSRBIP00000023765Uncharacterized protein. (330 aa)
BAIAP2BAI1 associated protein 2. (605 aa)
ITPR1Inositol 1,4,5-trisphosphate receptor type 1. (2749 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (306 aa)
SYKUncharacterized protein. (331 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
ITPR2Inositol 1,4,5-trisphosphate receptor type 2. (2637 aa)
ENSRBIP00000022670Uncharacterized protein. (281 aa)
ENSRBIP00000022666Uncharacterized protein. (379 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2161 aa)
ENSRBIP00000022174Ig-like domain-containing protein. (151 aa)
ENSRBIP00000021960Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (137 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (368 aa)
MYO1HMyosin IH; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1037 aa)
MYO1GMyosin IG; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1018 aa)
PAK1Non-specific serine/threonine protein kinase. (555 aa)
ENSRBIP00000020710Ig-like domain-containing protein. (124 aa)
ENSRBIP00000020593Ig-like domain-containing protein. (152 aa)
LOC108537061HATPase_c domain-containing protein. (384 aa)
ARPC1AActin related protein 2/3 complex subunit 1A. (279 aa)
WASHC1WASH complex subunit 1. (464 aa)
WIPF3WAS/WASL interacting protein family member 3. (423 aa)
TRAV22T cell receptor alpha variable 22. (147 aa)
ENSRBIP00000019284Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (169 aa)
IGLV3-19Immunoglobulin lambda variable 3-19. (143 aa)
WASF3WASP family member 3. (502 aa)
LOC108525261Uncharacterized protein. (75 aa)
ENSRBIP00000018225ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (125 aa)
ELMO3Engulfment and cell motility 3. (768 aa)
ENSRBIP00000018134Uncharacterized protein. (138 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
PLD5Phospholipase D family member 5. (536 aa)
ENSRBIP00000017624Ig-like domain-containing protein. (151 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
NCKAP1LNCK associated protein 1 like. (1134 aa)
WASLWASP like actin nucleation promoting factor. (504 aa)
ENSRBIP00000016972Ig-like domain-containing protein. (145 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
ENSRBIP00000016723Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (164 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
ENSRBIP00000016224Uncharacterized protein. (184 aa)
ENSRBIP00000015347Uncharacterized protein. (182 aa)
LOC108520315Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1900 aa)
ENSRBIP00000015229Ig-like domain-containing protein. (183 aa)
PLD3Phospholipase D family member 3. (490 aa)
ENSRBIP00000015006Uncharacterized protein. (131 aa)
FMN2Formin 2. (1620 aa)
PIK3R2Uncharacterized protein. (626 aa)
WIPF2WAS/WASL interacting protein family member 2. (439 aa)
MYO1DMyosin ID; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1015 aa)
NCKIPSDNCK interacting protein with SH3 domain. (722 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
NCK1NCK adaptor protein 1. (371 aa)
ARPC3Uncharacterized protein. (134 aa)
ENSRBIP00000012838Ig-like domain-containing protein. (159 aa)
ENSRBIP00000012540Ig-like domain-containing protein. (124 aa)
PIK3CBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (929 aa)
ENSRBIP00000011981Ig-like domain-containing protein. (148 aa)
ABI2Abl interactor 2. (463 aa)
IGLV6-57Immunoglobulin lambda variable 6-57. (149 aa)
ACTL7BActin like 7B; Belongs to the actin family. (399 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
PTK2Protein tyrosine kinase 2. (1078 aa)
LIMK1LIM domain kinase 1. (677 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (151 aa)
ENSRBIP00000009632Uncharacterized protein. (60 aa)
ENSRBIP00000009494Ig-like domain-containing protein. (178 aa)
DSTNDestrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (146 aa)
ACTR3BActin related protein 3B; Belongs to the actin family. (423 aa)
ENSRBIP00000009191Ig-like domain-containing protein. (153 aa)
ENSRBIP00000008952Ig-like domain-containing protein. (147 aa)
PLPP4Phospholipid phosphatase 4. (270 aa)
ENSRBIP00000008268Ig-like domain-containing protein. (186 aa)
ABL1Tyrosine-protein kinase. (1149 aa)
CD3GCD3g molecule. (181 aa)
MYO5AMyosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1765 aa)
PLD4Phospholipase D family member 4. (306 aa)
FYNTyrosine-protein kinase. (537 aa)
ENSRBIP00000005991Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (170 aa)
HSP90AB1-2HATPase_c domain-containing protein. (724 aa)
ACTRT1Actin related protein T1; Belongs to the actin family. (375 aa)
ABI1Abl interactor 1. (508 aa)
BRK1BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (375 aa)
ENSRBIP00000004532Ig-like domain-containing protein. (144 aa)
ACTBActin beta. (379 aa)
ARPC4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (189 aa)
CFL1Cofilin 1; Belongs to the actin-binding proteins ADF family. (189 aa)
HCKTyrosine-protein kinase. (517 aa)
SRCTyrosine-protein kinase. (627 aa)
ELMO1Engulfment and cell motility 1. (692 aa)
LOC108530360Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
ENSRBIP00000001398Ig-like domain-containing protein. (142 aa)
VAV2Vav guanine nucleotide exchange factor 2. (783 aa)
CRKCRK proto-oncogene, adaptor protein. (304 aa)
CFL2Cofilin 2; Belongs to the actin-binding proteins ADF family. (165 aa)
CD247CD247 molecule. (165 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (378 aa)
ENSRBIP00000000419Uncharacterized protein. (191 aa)
ENSRBIP00000000138Ig-like domain-containing protein. (159 aa)
Your Current Organism:
Rhinopithecus bieti
NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey
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