28 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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Your Input:
	PTGIS	Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family. (500 aa)
	LOC108519899	Uncharacterized protein; Belongs to the cytochrome P450 family. (514 aa)
	LOC108536550	Uncharacterized protein; Belongs to the cytochrome P450 family. (503 aa)
	FDXR	NADPH:adrenodoxin oxidoreductase, mitochondrial. (528 aa)
	POMC	Proopiomelanocortin. (251 aa)
	ARNT2	Aryl hydrocarbon receptor nuclear translocator 2. (723 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
	FDX2	2Fe-2S ferredoxin-type domain-containing protein. (185 aa)
	CYP51A1	Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (512 aa)
	CYP11A1	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (521 aa)
	CYP7B1	Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (505 aa)
	CYP7A1	Cytochrome P450 family 7 subfamily A member 1; Belongs to the cytochrome P450 family. (405 aa)
	CYP27A1	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (531 aa)
	NR1H4	Nuclear receptor subfamily 1 group H member 4. (481 aa)
	AHRR	Uncharacterized protein. (718 aa)
	ENSRBIP00000022080	Uncharacterized protein. (101 aa)
	NCOA1	Nuclear receptor coactivator. (1433 aa)
	CYP8B1	Cytochrome P450 family 8 subfamily B member 1; Belongs to the cytochrome P450 family. (496 aa)
	CYP46A1	Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (269 aa)
	FDX1	Ferredoxin 1. (184 aa)
	AHR	Uncharacterized protein. (833 aa)
	ENSRBIP00000035876	Uncharacterized protein. (120 aa)
	CYP39A1	Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (469 aa)
	CYP4V2	Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (525 aa)
	RXRA	Retinoid X receptor alpha. (492 aa)
	NCOA2	Nuclear receptor coactivator. (1475 aa)
	ARNT	Aryl hydrocarbon receptor nuclear translocator. (789 aa)
	CYP19A1	Cytochrome P450 family 19 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AHR	ARNT	ENSRBIP00000033680	ENSRBIP00000040761	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator.	0.994
AHR	ARNT2	ENSRBIP00000033680	ENSRBIP00000004781	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator 2.	0.972
AHR	CYP1B1	ENSRBIP00000033680	ENSRBIP00000005561	Uncharacterized protein.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.482
AHR	NCOA1	ENSRBIP00000033680	ENSRBIP00000022859	Uncharacterized protein.	Nuclear receptor coactivator.	0.700
AHR	NCOA2	ENSRBIP00000033680	ENSRBIP00000039622	Uncharacterized protein.	Nuclear receptor coactivator.	0.700
AHRR	ARNT	ENSRBIP00000021871	ENSRBIP00000040761	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator.	0.825
AHRR	ARNT2	ENSRBIP00000021871	ENSRBIP00000004781	Uncharacterized protein.	Aryl hydrocarbon receptor nuclear translocator 2.	0.825
AHRR	CYP1B1	ENSRBIP00000021871	ENSRBIP00000005561	Uncharacterized protein.	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family.	0.476
AHRR	NCOA1	ENSRBIP00000021871	ENSRBIP00000022859	Uncharacterized protein.	Nuclear receptor coactivator.	0.700
AHRR	NCOA2	ENSRBIP00000021871	ENSRBIP00000039622	Uncharacterized protein.	Nuclear receptor coactivator.	0.700
ARNT	AHR	ENSRBIP00000040761	ENSRBIP00000033680	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.994
ARNT	AHRR	ENSRBIP00000040761	ENSRBIP00000021871	Aryl hydrocarbon receptor nuclear translocator.	Uncharacterized protein.	0.825
ARNT	ARNT2	ENSRBIP00000040761	ENSRBIP00000004781	Aryl hydrocarbon receptor nuclear translocator.	Aryl hydrocarbon receptor nuclear translocator 2.	0.937
ARNT2	AHR	ENSRBIP00000004781	ENSRBIP00000033680	Aryl hydrocarbon receptor nuclear translocator 2.	Uncharacterized protein.	0.972
ARNT2	AHRR	ENSRBIP00000004781	ENSRBIP00000021871	Aryl hydrocarbon receptor nuclear translocator 2.	Uncharacterized protein.	0.825
ARNT2	ARNT	ENSRBIP00000004781	ENSRBIP00000040761	Aryl hydrocarbon receptor nuclear translocator 2.	Aryl hydrocarbon receptor nuclear translocator.	0.937
CYP11A1	CYP46A1	ENSRBIP00000014273	ENSRBIP00000031115	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family.	0.516
CYP11A1	CYP4V2	ENSRBIP00000014273	ENSRBIP00000038166	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family.	0.622
CYP11A1	CYP7B1	ENSRBIP00000014273	ENSRBIP00000014372	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family.	0.953
CYP11A1	FDX1	ENSRBIP00000014273	ENSRBIP00000032184	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Ferredoxin 1.	0.965