62 items (Rhinopithecus bieti) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NCOR2	Nuclear receptor corepressor 2. (2488 aa)
	ENSRBIP00000030441	SKIP_SNW domain-containing protein. (530 aa)
	HDAC9	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1066 aa)
	MAMLD1	Mastermind like domain containing 1. (1020 aa)
	RBPJ	Recombination signal binding protein for immunoglobulin kappa J region. (531 aa)
	HDAC3	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	MAML2	Mastermind like transcriptional coactivator 2. (1147 aa)
	CREBBP	CREB binding protein. (2422 aa)
	ENSRBIP00000020047	Uncharacterized protein; Belongs to the SKP1 family. (162 aa)
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1112 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (428 aa)
	HEY2	Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
	HES4	Hes family bHLH transcription factor 4. (188 aa)
	NOTCH1	Notch receptor 1. (2438 aa)
	HDAC10	Histone deacetylase 10. (673 aa)
	FBXW7	F-box and WD repeat domain containing 7. (707 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
	HES5	Hes family bHLH transcription factor 5. (152 aa)
	ENSRBIP00000027025	Hist_deacetyl domain-containing protein. (72 aa)
	ENSRBIP00000029173	Ubiquitin-like domain-containing protein. (166 aa)
	ENSRBIP00000029215	Uncharacterized protein. (283 aa)
	MAML1	Mastermind like transcriptional coactivator 1. (961 aa)
	LRBA	Uncharacterized protein. (2348 aa)
	RBX1	Ring-box 1. (108 aa)
	TLE3	TLE family member 3, transcriptional corepressor. (778 aa)
	NBEA	Uncharacterized protein. (739 aa)
	ENSRBIP00000039839	Uncharacterized protein; Belongs to the SKP1 family. (129 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (842 aa)
	SKP1	Uncharacterized protein; Belongs to the SKP1 family. (154 aa)
	SNW1	SKIP_SNW domain-containing protein. (536 aa)
	HDAC7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1011 aa)
	NCOR1	Nuclear receptor corepressor 1. (2441 aa)
	CDK8	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily. (482 aa)
	EP300	E1A binding protein p300. (2296 aa)
	MYC	Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (454 aa)
	HEYL	Hes related family bHLH transcription factor with YRPW motif like. (328 aa)
	RPS27A	Ubiquitin-like domain-containing protein. (156 aa)
	ENSRBIP00000001317	Ubiquitin-like domain-containing protein. (155 aa)
	ENSRBIP00000002474	Uncharacterized protein. (339 aa)
	LOC108544295	Uncharacterized protein; Belongs to the SKP1 family. (163 aa)
	ENSRBIP00000003802	Ubiquitin-like domain-containing protein. (84 aa)
	ENSRBIP00000004187	Ubiquitin-like domain-containing protein. (153 aa)
	HEY1	Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
	TBL1XR1	Transducin beta like 1 X-linked receptor 1. (514 aa)
	KAT2A	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
	KAT2B	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (798 aa)
	UBA52	Ubiquitin-like domain-containing protein. (232 aa)
	TBL1X	Transducin beta like 1 X-linked. (586 aa)
	ENSRBIP00000008820	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (470 aa)
	TLE2	TLE family member 2, transcriptional corepressor. (769 aa)
	HES1	Hes family bHLH transcription factor 1. (277 aa)
	HDAC6	Histone deacetylase 6. (1215 aa)
	HDAC11	Histone deacetylase 11. (347 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	TLE1	TLE family member 1, transcriptional corepressor. (770 aa)
	TLE4	TLE family member 4, transcriptional corepressor. (799 aa)
	LOC108532627	Hist_deacetyl domain-containing protein. (210 aa)
	LOC108527145	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (469 aa)
	HDAC5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1123 aa)
	ENSRBIP00000018271	Hist_deacetyl domain-containing protein. (180 aa)
	CCNC	Cyclin C; Belongs to the cyclin family. (265 aa)
	HDAC8	Hist_deacetyl domain-containing protein. (103 aa)

Your Current Organism:

Rhinopithecus bieti

NCBI taxonomy Id: 61621
Other names: Pygathrix bieti, R. bieti, black snub-nosed monkey

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCNC	CDK8	ENSRBIP00000018560	ENSRBIP00000034149	Cyclin C; Belongs to the cyclin family.	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	0.997
CDK8	CCNC	ENSRBIP00000034149	ENSRBIP00000018560	Cyclin dependent kinase 8; Belongs to the protein kinase superfamily.	Cyclin C; Belongs to the cyclin family.	0.997
CREBBP	ENSRBIP00000008820	ENSRBIP00000030593	ENSRBIP00000008820	CREB binding protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.607
CREBBP	ENSRBIP00000018271	ENSRBIP00000030593	ENSRBIP00000018271	CREB binding protein.	Hist_deacetyl domain-containing protein.	0.607
CREBBP	ENSRBIP00000027025	ENSRBIP00000030593	ENSRBIP00000027025	CREB binding protein.	Hist_deacetyl domain-containing protein.	0.523
CREBBP	ENSRBIP00000030441	ENSRBIP00000030593	ENSRBIP00000030441	CREB binding protein.	SKIP_SNW domain-containing protein.	0.639
CREBBP	EP300	ENSRBIP00000030593	ENSRBIP00000033605	CREB binding protein.	E1A binding protein p300.	0.998
CREBBP	HDAC1	ENSRBIP00000030593	ENSRBIP00000021727	CREB binding protein.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.607
CREBBP	HDAC10	ENSRBIP00000030593	ENSRBIP00000022896	CREB binding protein.	Histone deacetylase 10.	0.462
CREBBP	HDAC11	ENSRBIP00000030593	ENSRBIP00000012499	CREB binding protein.	Histone deacetylase 11.	0.481
CREBBP	HDAC2	ENSRBIP00000030593	ENSRBIP00000024152	CREB binding protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.668
CREBBP	HDAC3	ENSRBIP00000030593	ENSRBIP00000033210	CREB binding protein.	Histone deacetylase 3; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4), and some other non-histone substrates. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.631
CREBBP	HDAC4	ENSRBIP00000030593	ENSRBIP00000021353	CREB binding protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.520
CREBBP	HDAC5	ENSRBIP00000030593	ENSRBIP00000018063	CREB binding protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.517
CREBBP	HDAC6	ENSRBIP00000030593	ENSRBIP00000010703	CREB binding protein.	Histone deacetylase 6.	0.603
CREBBP	HDAC7	ENSRBIP00000030593	ENSRBIP00000035594	CREB binding protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.573
CREBBP	HDAC8	ENSRBIP00000030593	ENSRBIP00000019403	CREB binding protein.	Hist_deacetyl domain-containing protein.	0.523
CREBBP	HDAC9	ENSRBIP00000030593	ENSRBIP00000019859	CREB binding protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.529
CREBBP	HIF1A	ENSRBIP00000030593	ENSRBIP00000039047	CREB binding protein.	Hypoxia inducible factor 1 subunit alpha.	0.998
CREBBP	KAT2A	ENSRBIP00000030593	ENSRBIP00000006524	CREB binding protein.	Histone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily.	0.986